The unmet need in rheumatology

Autor: Ronald F van Vollenhoven, Vibeke Strand, Joan M. Bathon, Désirée van der Heijde, Mary K. Crow, Michael E. Weinblatt, Gerd R Burmester, Joachim Sieper, Xavier Mariette, Joachim R. Kalden, Maxime Dougados, Philip J. Mease, Josef S Smolen, Ferdinand C. Breedfeld, Johnathan Kay, Daniel E. Furst, Fritz Melchers, Kevin L. Winthrop

Publikováno v: Winthrop, K L, Strand, V, van der Heijde, D, Mease, P, Crow, M, Weinblatt, M, Bathon, J, Burmester, G R, Dougados, M, Kay, J, Mariette, X, Van Vollenhoven, R, Sieper, J, Melchers, F, Breedfeld, F C, Kalden, J, Smolen, J S & Furst, D E 2018, ' The unmet need in rheumatology : Reports from the targeted therapies meeting 2017 ', Clinical Immunology, vol. 186, pp. 87-93 . https://doi.org/10.1016/j.clim.2017.08.009
Clinical immunology (Orlando, Fla.), 186, 87-93. Academic Press Inc.
Clinical Immunology, 186, 87-93. Academic Press Inc.

The 19th annual international Targeted Therapies meeting brought together over 100 leading basic scientists and clinical researchers from around the world in the field of immunology, molecular biology and rheumatology and other specialties. During th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d84c835e43593bf67cc37a6aa12ec0
http://www.scopus.com/inward/record.url?scp=85028377533&partnerID=8YFLogxK

Immunology in Germany: 50th Anniversary of the German Society for Immunology (DGfI)

Autor: Hans-Martin Jäck, Agnes Giniewski, Joachim R. Kalden

Publikováno v: European Journal of Immunology. 47:2012-2016

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89af59a584e72b8ef454bb9df75f1adc
https://doi.org/10.1002/eji.201770125

Emerging Therapies for Rheumatoid Arthritis

Autor: Joachim R. Kalden

Publikováno v: Rheumatology and Therapy. 3:31-42

Diverse strategies to develop novel treatments for rheumatoid arthritis which specifically target those patients who do not respond to available medications, including biologics, are currently being explored. New potential therapeutic approaches whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c961c18d52ca41fa9af6c1d2e0cc859c
https://doi.org/10.1007/s40744-016-0032-4

Induction of proliferation and pro-inflammatory cytokine production in rheumatoid arthritis peripheral blood mononuclear cells by a 65 KDa chondrocyte membrane-specific, constitutive target autoantigen (CH65)

Autor: Joachim R. Kalden, S Alsalameh, Rayya J. Alsalameh, Gerd R Burmester, Jürgen Mollenhauer, Rachael C. Casey

Publikováno v: International Journal of Rheumatic Diseases. 20:1132-1141

Objective To analyze proliferation and pro-inflammatory cytokine production of peripheral blood mononuclear cells (PBMC) from rheumatoid arthritis (RA) patients following stimulation with a purified chondrocyte membrane-associated autoantigen (CH65).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3e2b7f5d8473936a6837360eca0dba
https://doi.org/10.1111/1756-185x.12167

Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis

Autor: Josef S Smolen, Burkhard F. Leeb, Thomas F. Schaible, Ravinder N. Maini, Ferdinand C. Breedveld, C Antoni, M J Elliott, Marc Feldmann, Joachim R. Kalden, James N. Woody, Diana Davis, John D. Macfarlane

OBJECTIVE: To evaluate the efficacy, pharmacokinetics, immunogenicity, and safety of multiple infusions of a chimeric monoclonal anti-tumor necrosis factor alpha antibody (cA2) (infliximab; Remicade, Centocor, Malvern, PA) given alone or in combinati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1e91ab0dbab56470fe0c95b3dd9941
https://ora.ox.ac.uk/objects/uuid:b6cd2920-1f1e-459a-a290-55e23d9d26e6