Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Joachim O Rädler"'
Autor:
Fang Zhou, Sophia A Schaffer, Christoph Schreiber, Felix J Segerer, Andriy Goychuk, Erwin Frey, Joachim O Rädler
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230679 (2020)
Cell migration on microlanes represents a suitable and simple platform for the exploration of the molecular mechanisms underlying cell cytoskeleton dynamics. Here, we report on the quasi-periodic movement of cells confined in stripe-shaped microlanes
Externí odkaz:
https://doaj.org/article/16023251543c4955aa23d18c87044bdd
Autor:
Bojan Ljepoja, Christoph Schreiber, Florian A Gegenfurtner, Jonathan García-Roman, Bianca Köhler, Stefan Zahler, Joachim O Rädler, Ernst Wagner, Andreas Roidl
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224314 (2019)
Cancer progression and metastases are frequently related to changes of cell motility. Amongst others, the microRNA-200c (miR-200c) was shown to maintain the epithelial state of cells and to hamper migration. Here, we describe two miR-200c inducible b
Externí odkaz:
https://doaj.org/article/1fd649239240459e99eae4b55d1facc4
Autor:
Georg Fritz, Judith A Megerle, Sonja A Westermayer, Delia Brick, Ralf Heermann, Kirsten Jung, Joachim O Rädler, Ulrich Gerland
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89532 (2014)
Inducible switching between phenotypes is a common strategy of bacteria to adapt to fluctuating environments. Here, we analyze the switching kinetics of a paradigmatic inducible system, the arabinose utilization system in E. coli. Using time-lapse fl
Externí odkaz:
https://doaj.org/article/8e9b9cba466e4bb5930b39d674a05528
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107148 (2014)
Recent work on the use of mRNA lipoplexes for gene delivery demonstrates the need for a mathematical model that simulates and predicts kinetics and transfection efficiency. The small copy numbers involved make it necessary to use stochastic models an
Externí odkaz:
https://doaj.org/article/ad5ab3ed97b3420aa4a4da70e562aa66
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Quantitative studies of mesenchymal cell motion are important to elucidate cytoskeleton function and mechanisms of cell migration. To this end, confinement of cell motion to one dimension (1D) significantly simplifies the problem of cell shape in exp
Externí odkaz:
https://doaj.org/article/0499aa7c63064350869ff6d2a36d73a9
Publikováno v:
Lab on a Chip. 23:1886-1895
We present microfabricated hydrogel clefts, ‘sponge clamps’, made of polyethylene glycol-norbornene (PEG-NB) with defined geometry, stiffness and adhesiveness for the study of cell invasion.
Publikováno v:
Biophysical Journal. 121:2557-2567
Cell migration on an adhesive substrate surface comprises actin-based protrusion at the front and retraction of the tail in combination with coordinated adhesion to, and detachment from, the substrate. To study the effect of cell-to-substrate adhesio
Autor:
Tamara Ehm, Julian Philipp, Martin Barkey, Martina Ober, Achim Theo Brinkop, David Simml, Miriam von Westphalen, Bert Nickel, Roy Beck, Joachim O. Rädler
Publikováno v:
Journal of Synchrotron Radiation. 29:1014-1019
3D printing changes the scope of how samples can be mounted for small-angle X-ray scattering (SAXS). In this paper a 3D-printed X-ray chamber, which allows for in situ exchange of buffer and in situ optical transmission spectroscopy, is presented. Th
Autor:
Tamara Ehm, Hila Shinar, Guy Jacoby, Sagi Meir, Gil Koren, Merav Segal Asher, Joanna Korpanty, Matthew P. Thompson, Nathan C. Gianneschi, Michael M. Kozlov, Salome Emma Azoulay-Ginsburg, Roey J. Amir, Joachim O. Rädler, Roy Beck
Publikováno v:
Biomacromolecules 24(1), 98 – 108 (2023). doi:10.1021/acs.biomac.2c00866
Biomacromolecules 24(1), 98 – 108 (2023). doi:10.1021/acs.biomac.2c00866
Intrinsically disordered peptide amphiphiles (IDPAs) present a novel class of synthetic conjugates that consist of short hydrophilic polypeptides anchored to hydrocarbon
Intrinsically disordered peptide amphiphiles (IDPAs) present a novel class of synthetic conjugates that consist of short hydrophilic polypeptides anchored to hydrocarbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7669bc50d90163fa3462b835e058177b
Autor:
David B. Brückner, Matthew Schmitt, Alexandra Fink, Georg Ladurner, Johannes Flommersfeld, Nicolas Arlt, Edouard Hannezo, Joachim O. Rädler, Chase P. Broedersz
Publikováno v:
Physical Review X, 12(3):031041, 1-23. American Physical Society
Brückner, D B, Schmitt, M, Fink, A, Ladurner, G, Flommersfeld, J, Arlt, N, Hannezo, E, Rädler, J O & Broedersz, C P 2022, ' Geometry Adaptation of Protrusion and Polarity Dynamics in Confined Cell Migration ', Physical Review X, vol. 12, no. 3, 031041, pp. 1-23 . https://doi.org/10.1103/PhysRevX.12.031041
Brückner, D B, Schmitt, M, Fink, A, Ladurner, G, Flommersfeld, J, Arlt, N, Hannezo, E, Rädler, J O & Broedersz, C P 2022, ' Geometry Adaptation of Protrusion and Polarity Dynamics in Confined Cell Migration ', Physical Review X, vol. 12, no. 3, 031041, pp. 1-23 . https://doi.org/10.1103/PhysRevX.12.031041
Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and the cell nucleus. However, it remains poorly understood how the dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef0e34efdf5b50ce226533af5fe8557
https://research.vu.nl/en/publications/a9422e1e-70fc-47a6-a232-a1c4ec0d1683
https://research.vu.nl/en/publications/a9422e1e-70fc-47a6-a232-a1c4ec0d1683