Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Joachim M, Mayer"'
Autor:
Jérôme Berger, M. Reist, Olivia Felt-Baeyens, Robert Gurny, Abdellatif Chenite, Joachim M. Mayer
Publikováno v:
International Journal of Pharmaceutics, Vol. 288, No 2 (2005) pp. 197-206
Unisciences
Unisciences
To prepare transparent chitosan/beta-glycerophosphate (betaGP) pseudo-thermosetting hydrogels, the deacetylation degree (DD) of chitosan has been modified by reacetylation with acetic anhydride. Two methods (I and II) of reacetylation have been compa
Autor:
Marko K. Ivancevic, Catherine M. Pastor, Sibylle Pochon, Joachim M. Mayer, François Terrier, Corinne Planchamp, Jean-Paul Vallée, Marianne Reist
Publikováno v:
Biotechnology and Bioengineering. 85:656-665
The aim of our study was to develop a magnetic resonance (MR)-compatible in vitro model containing freshly isolated rat hepatocytes to study the transport of hepatobiliary contrast agents (CA) by MR imaging (MRI). We set up a perfusion system includi
Autor:
Corinne, Planchamp, Marko K, Ivancevic, Catherine M, Pastor, Jean-Paul, Vallée, Sibylle, Pochon, François, Terrier, Joachim M, Mayer, Marianne, Reist
Publikováno v:
Biotechnology and bioengineering
Biotechnology and Bioengineering, Vol. 85, No 6 (2004) pp. 656-65
Biotechnology and Bioengineering, Vol. 85, No 6 (2004) pp. 656-65
The aim of our study was to develop a magnetic resonance (MR)-compatible in vitro model containing freshly isolated rat hepatocytes to study the transport of hepatobiliary contrast agents (CA) by MR imaging (MRI). We set up a perfusion system includi
Publikováno v:
Entropy, Vol 3, Iss 2, Pp 27-57 (2001)
Entropy
Volume 3
Issue 2
Pages 27-57
Entropy
Volume 3
Issue 2
Pages 27-57
In a recent study by Kier, Cheng and Testa, simulations were carried out to monitor and quantify the emergence of a collective phenomenon, namely percolation, in a many-particle system modeled by cellular automata (CA). In the present study, the same
Publikováno v:
International Journal of Pharmaceutics, Vol. 180, No 2 (1999) pp. 185-193
The mucoadhesive polysaccharide chitosan was evaluated as a potential component in ophthalmic gels for enabling increased precorneal drug residence times. This cationic vehicle was expected to slow down drug elimination by the lacrymal flow both by i
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 47, No 2 (1999) pp. 105-112
We investigated the effects of instilling 13 commonly used preservatives on the murine cornea in vivo. Due to the instillation of preservatives, micro-lesions are formed on the cornea and can be selectively marked by fluorescein. The sum of the resul
Autor:
Joachim M. Mayer, Bernard Testa
Publikováno v:
Il Farmaco. 53:287-291
Drug metabolism has a number of pharmacodynamic and pharmacokinetic consequences which cannot be ignored even at the early stages of drug research. A number of aspects of drug metabolism are thus of interest to medicinal chemists, e.g. prodrug and so
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 13:559-578
In recent years, confocal microscopy has become a powerful tool for examining microscopic structures in the living eye. The decisive advantage of this technique is that it permits the investigation of optical sections of relatively thick (> 10 μm) s
Publikováno v:
Biochemical Pharmacology. 47:753-756
Publikováno v:
Chirality. 2:74-78
Ibuprofen was used to demonstrate that isolated rat hepatocytes offer a suitable in vitro model to investigate the metabolic chiral inversion of anti-inflammatory 2-arylpropionic acids (profens). The inversion of the pharmacologically inactive (-)-(R