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pro vyhledávání: '"Joachim Leibrock"'
Autor:
Hartmut Greiner, Clas Sonesson, Jörg Plaschke, Cecilia Mattsson, Joachim Leibrock, Henning Böttcher, Michael Gassen, Anna Sandahl
Publikováno v:
ChemInform. 36
A series of 2-alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles were synthesized and evaluated for their 5-HT6 activity. The most potent agonist in this series was 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole with an IC50 = 7.4 nM
Publikováno v:
Scopus-Elsevier
The survival and functional maintenance of vertebrate neurons critically depends on the availability of specific neurotrophic factors. So far, only two such factors, nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) have been cha
Publikováno v:
The EMBO journal. 9(11)
The mRNAs of nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) exhibit a similar, though not identical, regional and cellular distribution in the rodent brain. In situ hybridization experiments have shown that BDNF, like NGF, is
Publikováno v:
Molecular and General Genetics MGG. 192:66-72
We have determined the arrangement of the ribosomal RNA genes of eight archaebacteria, representative of the two main divisions of this urkingdom, by Southern hybridization of purified 32P-labeled 5S, 16S and 23S rRNA to chromosomal DNA fragmented wi
Autor:
Piotr Masiakowski, Friedrich Lottspeich, Joachim Leibrock, Hans Thoenen, Bastian Hengerer, Yves-Alain Barde, Hohn Andreas, Magdalena Hofer
Publikováno v:
Scopus-Elsevier
During the development of the vertebrate nervous system, many neurons depend for survival on interactions with their target cells. Specific proteins are thought to be released by the target cells and to play an essential role in these interactions. S