Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joachim L. Petit"'
Autor:
Michelle Kassner, J. Brek Eaton, Nanyun Tang, Joachim L. Petit, Nathalie Meurice, Hongwei Holly Yin, Paul Whiteaker
Publikováno v:
SLAS Discovery, Vol 27, Iss 1, Pp 68-76 (2022)
There is substantial evidence that in addition to nicotine, other compounds found in tobacco smoke significantly influence smoking behavior. Further, recent years have seen an explosion in the availability of non-combusted products that deliver nicot
Externí odkaz:
https://doaj.org/article/69bed0571f2b4e86ad58d7d3b8564877
Autor:
Cecilia Bonolo de Campos, Yuan Xiao Zhu, Nikolai Sepetov, Sergei Romanov, Laura Ann Bruins, Chang-Xin Shi, Caleb K. Stein, Joachim L. Petit, Alysia N. Polito, Meaghen E. Sharik, Erin W. Meermeier, Gregory J. Ahmann, Ilsel D. Lopez Armenta, Jonas Kruse, P. Leif Bergsagel, Marta Chesi, Nathalie Meurice, Esteban Braggio, A. Keith Stewart
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
The cellular cytotoxicity of APY0201, a PIKfyve inhibitor, against multiple myeloma was initially identified in an unbiased in vitro chemical library screen. The activity of APY0201 was confirmed in all 25 cell lines tested and in 40% of 100 ex vivo
Externí odkaz:
https://doaj.org/article/36f9707664964168a6cc9caa0c85b080
Autor:
Douglas F. Lake, Thai H. Ho, Huijun Luo, Shamit K. Dutta, Krishnendu Pal, Debabrata Mukhopadhyay, John A. Copland, Erik P. Castle, Thomas R. Caulfield, Alysia Polito, Joachim L. Petit, Nathalie Meurice, Andrey Bobkov, Eduard Sergienko, Douglas O. Faigel, Paul D. Hanavan, Amber L. Fifield
*Supplementary Figure 1 shows the chemical structure of SBI-183. *Supplementary Figure 2 displays the verification of shRNA KD of QSOX1 by qRT-PCR. *Supplementary Table 1 shows the results from our docking protocols. *Supplementary Figure 3 displays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0812ae1752e6a7688f19f5d7d993e2a7
https://doi.org/10.1158/1535-7163.22507063
https://doi.org/10.1158/1535-7163.22507063
Autor:
Douglas F. Lake, Thai H. Ho, Huijun Luo, Shamit K. Dutta, Krishnendu Pal, Debabrata Mukhopadhyay, John A. Copland, Erik P. Castle, Thomas R. Caulfield, Alysia Polito, Joachim L. Petit, Nathalie Meurice, Andrey Bobkov, Eduard Sergienko, Douglas O. Faigel, Paul D. Hanavan, Amber L. Fifield
Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme overexpressed by many different tumor types. QSOX1 catalyzes the formation of disulfide bonds in proteins. Because short hairpin knockdowns (KD) of QSOX1 have been shown to suppress tumor growth and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfd2637f0dcaafeb2948040e6fbd1e9
https://doi.org/10.1158/1535-7163.c.6538567.v1
https://doi.org/10.1158/1535-7163.c.6538567.v1
Autor:
Sanjeev Shukla, Mohammed Al-Toubat, Carlos Riveros, Allison H. Feibus, Ahmed El-shafie, Adam M. Kase, John A. Copland, Joachim L. Petit, Nathalie Meurice, Justyna Gleba, Jonathan Chardon-Robles, Teruko Osumi, K. C. Balaji
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8009a34a2e69eb25ca580ff1116013a2
https://doi.org/10.1097/ju.0000000000003228.07
https://doi.org/10.1097/ju.0000000000003228.07
Autor:
Gregory J. Gores, Hani M. Babiker, Alexander T. Baker, Daniel H. Ahn, George Vasmatzis, Benjamin R. Kipp, Rish K. Pai, Bertram L. Jacobs, James M Bogenberger, Nathalie Meurice, Rory L. Smoot, Oumar Barro, Marcela Salomao, Mansi Arora, Chelsae Dumbauld, Bolni Marius Nagalo, Michael T. Barrett, Mitesh J. Borad, Natalie Elliott, Heidi E. Kosiorek, Tanios Bekaii-Saab, Thomas DeLeon, Faaiq N Aslam, Yumei Zhou, Pedro Luiz Serrano Uson Junior, Mohammad Bassam Sonbol, Kenneth H. Buetow, Joachim L. Petit, Jun Yin, Aaron S. Mansfield, Amit Mahipal
Publikováno v:
Digestive Diseases and Sciences. 67:3797-3805
FGFR2 genomic alterations are observed in 10–20% of cholangiocarcinoma (CCA). Although FGFR2 fusions are an important actionable target, FGFR2 protein expression has not been thoroughly characterized. To evaluate FGFR2 protein expression in cholang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a81957375468a6f6931cec77d534b7
https://doi.org/10.1007/s10620-021-07303-9
https://doi.org/10.1007/s10620-021-07303-9
Autor:
Sanjeev Shukla, Mohammed Al-Toubat, Allison H. Feibus, Ahmed Elshafei, Carlos Riveros, Nathalie Meurice, Justyna Gleba, Jonathan Chardon-Robles, Adam M. Kase, John A. Copland III, Joachim L. Petit, Teruko Osumi, K.C. Balaji
Publikováno v:
Cancer Research. 83:2475-2475
Bromodomains (BD) are epigenetic readers of histone acetylation involved in chromatin remodeling and transcriptional regulation of protooncogene cellular myelocytomatosis (c- Myc) and other genes. Because c-Myc cannot be directly targeted by small mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5a72008e42ddd90f768d373e0014686
https://doi.org/10.1158/1538-7445.am2023-2475
https://doi.org/10.1158/1538-7445.am2023-2475
Autor:
Nathalie Meurice, Debabrata Mukhopadhyay, Krishnendu Pal, Alysia N. Polito, Thai H. Ho, Paul D. Hanavan, Andrey A. Bobkov, Huijun Luo, Douglas O. Faigel, Shamit K. Dutta, Eduard Sergienko, Amber Fifield, John A. Copland, Erik P. Castle, Thomas R. Caulfield, Joachim L. Petit, Douglas F. Lake
Publikováno v:
Molecular Cancer Therapeutics. 19:112-122
Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme overexpressed by many different tumor types. QSOX1 catalyzes the formation of disulfide bonds in proteins. Because short hairpin knockdowns (KD) of QSOX1 have been shown to suppress tumor growth and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45ab4c85fec91d4ee718f888c8fb8505
https://doi.org/10.1158/1535-7163.mct-19-0233
https://doi.org/10.1158/1535-7163.mct-19-0233
Autor:
Rory L. Smoot, Natasha Wylie, Chelsae Dumbauld, Uson Junior Pls, Jason S. Starr, Michael T. Barrett, Jun Yin, Mansi Arora, Hani M. Babiker, T. S. Bekaii-Saab, Gregory J. Gores, Nathalie Meurice, Alexander T. Baker, Kenneth H. Buetow, Joachim L. Petit, Elliott N, Bolni Marius Nagalo, Daniel H. Ahn, Umair Majeed, Aaron S. Mansfield, Inabinett, Jeremy Clifton Jones, Yumei Zhou, Kabir Mody, Mitesh J. Borad, Ashton W. Boyle, James M Bogenberger, Oumar Barro, Mohamad Bassam Sonbol, Gehan Botrus
PURPOSEThis investigation sough to evaluate the prognostic value of pre-treatment ctDNA in metastatic biliary tract cancers (BTC) treated with platinum based first-line chemotherapy treatment.METHODSWe performed a retrospective analysis of 67 patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::471d09cb5f9b37a2fed2893aeb6de50f
https://doi.org/10.1101/2021.11.01.21265773
https://doi.org/10.1101/2021.11.01.21265773
Autor:
Seth J Welsh, Benjamin G Barwick, Erin Meermeier, Daniel Riggs, Chang-Xin Shi, Yuan Xiao Zhu, Meaghen E Sharik, Megan T Du, Victoria Marie Garbitt, Caleb K Stein, Joachim L Petit, Nathalie Meurice, Rodrigo Fonseca, Kennedi Todd, Sochilt Brown, Yuliza Tafoya Alvarado, Zachary Hammond, Nicklus Cuc, Courtney Wittenberg, Camille Herzog, Lawrence H. Boise, Nizar J. Bahlis, Paola Neri, W. Michael Kuehl, Marta Chesi, P. Leif Bergsagel
Publikováno v:
Blood. 140:12997-12997
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b491f69a1ecb5b41cf45db61fcba511a
https://doi.org/10.1182/blood-2022-169920
https://doi.org/10.1182/blood-2022-169920