Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Joachim Kutzera"'
Autor:
Jose Espejo Valle-Inclan, Nicolle J.M. Besselink, Ewart de Bruijn, Daniel L. Cameron, Jana Ebler, Joachim Kutzera, Stef van Lieshout, Tobias Marschall, Marcel Nelen, Peter Priestley, Ivo Renkens, Margaretha G.M. Roemer, Markus J. van Roosmalen, Aaron M. Wenger, Bauke Ylstra, Remond J.A. Fijneman, Wigard P. Kloosterman, Edwin Cuppen
Publikováno v:
Cell Genomics, Vol 2, Iss 6, Pp 100139- (2022)
Summary: Accurate detection of somatic structural variation (SV) in cancer genomes remains a challenging problem. This is in part due to the lack of high-quality, gold-standard datasets that enable the benchmarking of experimental approaches and bioi
Externí odkaz:
https://doaj.org/article/f08ff7a8abe64b31bdcb821bc498cd0a
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139704 (2015)
Protein interaction in cells can be described at different levels. At a low interaction level, proteins function together in small, stable complexes and at a higher level, in sets of interacting complexes. All interaction levels are crucial for the l
Externí odkaz:
https://doaj.org/article/3647c5c64fea4a4cb0b70fbe07f72b69
Autor:
Alaa Embaby, Jill Jacqueline Geenen, Joachim Kutzera, Dick Pluim, Marta I. Lopez-Yurda, Jos H. Beijnen, Alwin Huitema, Petronella Witteveen, Neeltje Steeghs, Gijs van Haaften, Marcel A.T.M. van Vugt, Jeroen de Ridder, Frans Opdam
Publikováno v:
Journal of Clinical Oncology. 40:5516-5516
5516 Background: Ovarian cancer is globally the second most common cause of death among women with gynecologic malignancies. Despite high initial response rates, the overall prognosis of this patient population remains poor. The majority of advanced
Autor:
Jose Espejo Valle-Inclan, Ivo Renkens, Aaron M. Wenger, Peter Priestley, Ewart de Bruijn, Joachim Kutzera, Tobias Marschall, Wigard P. Kloosterman, Markus J. van Roosmalen, Jana Ebler, Edwin Cuppen, Bauke Ylstra, Margaretha G.M. Roemer, Nicolle Besselink, Stef van Lieshout, Remond J.A. Fijneman, Marcel R. Nelen, Andy Wing Chun Pang, Daniel L Cameron
Accurate detection of somatic structural variation (SV) in cancer genomes remains a challenging problem. This is in part due to the lack of high-quality gold standard datasets that enable the benchmarking of experimental approaches and bioinformatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceab79b7f6137c26ea36afdba81532cf
https://doi.org/10.1101/2020.10.15.340497
https://doi.org/10.1101/2020.10.15.340497
Autor:
Arne Van Hoeck, Chris J. de Witte, Ronald P. Zweemer, Wigard P. Kloosterman, Christa van Schaik van de Mheen, Luan Nguyen, Edwin Cuppen, Petronella O. Witteveen, Marion Stevense, Petronella B. Ottevanger, Joachim Kutzera, Mathilde Jalving, Ingrid A. Boere
Publikováno v:
Cancers, 14(6):1511. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 14(6):1511. MDPI AG
Cancers, 14, 6
Cancers, 14
Cancers; Volume 14; Issue 6; Pages: 1511
Cancers, 14(6):1511. MDPI AG
Cancers, 14, 6
Cancers, 14
Cancers; Volume 14; Issue 6; Pages: 1511
The majority of patients with ovarian cancer ultimately develop recurrent chemotherapy resistant disease. Treatment stratification is mainly based on histological subtype and stage, prior response to platinum-based chemotherapy and time to recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2643941057090a8cc91bb95a96757502
https://doi.org/10.1101/2020.06.04.20118976
https://doi.org/10.1101/2020.06.04.20118976
Autor:
Hannah S. van Meurs, Joachim Kutzera, Gijs van Haaften, Ronald P. Zweemer, S. T. Paijens, Glen R. Monroe, Petronella O. Witteveen, Christianne A.R. Lok, Ellen Stelloo, Luc R.C.W. van Lonkhuijzen, J. W. Groeneweg, René H.M. Verheijen, Jurgen M.J. Piek, Hans W. Nijman, Geertruida N. Jonges, Joline F. Roze
Publikováno v:
Cancers, Vol 12, Iss 1308, p 1308 (2020)
Cancers, 12(5):1308. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Volume 12
Issue 5
Cancers, 12(5):1308. MDPI AG
Cancers, 12(5):1308. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Volume 12
Issue 5
Cancers, 12(5):1308. MDPI AG
Adult granulosa cell tumors (AGCTs) harbor a somatic FOXL2 c.402C>
G mutation in ~95% of cases and are mainly surgically removed due to limited systemic treatment effect. In this study, potentially targetable genomic alterations in AGCTs were
G mutation in ~95% of cases and are mainly surgically removed due to limited systemic treatment effect. In this study, potentially targetable genomic alterations in AGCTs were
Autor:
Joline F. Roze, Petronella O. Witteveen, Joachim Kutzera, Hans W. Nijman, Jmj Piek, Car Lok, R.H.M. Verheijen, Lrcw van Lonkhuijzen, J. W. Groeneweg, Geertruida N. Jonges, Ellen Stelloo, Ronald P. Zweemer, S. T. Paijens, H. S. van Meurs, Glen R. Monroe, G van Haaften
Adult granulosa cell tumors (AGCTs) harbor a somatic FOXL2 c.402C>G mutation in ∼95% of cases and are mainly surgically removed due to limited systemic treatment effect. In this study, potentially targetable genomic alterations in AGCTs were invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f7a88f1ac4b9710042bd0ac77903a3
Autor:
Ronald P. Zweemer, CJ de Witte, MJ van Roosmalen, Joachim Kutzera, Wigard P. Kloosterman, Edwin Cuppen, Petronella O. Witteveen, J Espejo Valle-Inclan, Sander Boymans
Publikováno v:
ePoster.
Introduction/Background While most patients with ovarian cancer are initially sensitive to chemotherapy, approximately 75% will develop recurrent disease and become resistant. Predicted response to platinum is considered important in deciding on the
Autor:
Sung Yun Jung, Maxime W.C. Rousseaux, Yin Huang, Suman Maity, Yi Wang, Joachim Kutzera, Jean J. Kim, Huda Y. Zoghbi, Jong Min Choi, Jun Qin, Anna Malovannaya, Weimin Zhu
Publikováno v:
Molecular & Cellular Proteomics. 16:581-593
Here, we present a mouse brain protein atlas that covers 17 surgically distinct neuroanatomical regions of the adult mouse brain, each less than 1 mm3 in size. The protein expression levels are determined for 6,500 to 7,500 gene protein products from
Autor:
Patrick May, Joachim Kutzera
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783319697505
DILS
DILS
Next Generation Sequencing (NGS) allows sequencing of a human genome within hours, enabling large scale applications such as sequencing the genome of each patient in a clinical study. Each individual human genome has about 3.5 Million genetic differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9211f82be682637beebc8a01a7b26902
https://doi.org/10.1007/978-3-319-69751-2_3
https://doi.org/10.1007/978-3-319-69751-2_3