Zobrazeno 1 - 10
of 572
pro vyhledávání: '"Joachim D. Uys"'
Autor:
Jacqueline S. Womersley, Clémence Obellianne, Audrey E. Padula, Marcelo F. Lopez, William C. Griffin, Lauren E. Ball, Stefano Berto, Kathleen A. Grant, Danyelle M. Townsend, Joachim D. Uys, Patrick J. Mulholland
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117514- (2024)
Alcohol use disorder (AUD) is the most prevalent substance use disorder but there is incomplete knowledge of the underlying molecular etiology. Here, we examined the cytosolic proteome from the nucleus accumbens core (NAcC) of ethanol drinking rhesus
Externí odkaz:
https://doaj.org/article/065fd24f7c074ee98ae105b126d2ddbc
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223037 (2019)
Neuronal defense against oxidative damage is mediated primarily by the glutathione redox system. Traditionally considered a mechanism to protect proteins from irreversible oxidation, mounting evidence supports a role for protein S-glutathionylation i
Externí odkaz:
https://doaj.org/article/f90ecbb94ade43dfba284f90330d2168
Autor:
Kenneth D. Tew, Christopher J. Pazoles, Woodrow J. Coker, Yefim Manevich, Joachim D. Uys, Danyelle M. Townsend, Christina L. Grek
PDF file - 84K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2224690926e40ac9db5c6316788503c7
https://doi.org/10.1158/0008-5472.22395419
https://doi.org/10.1158/0008-5472.22395419
Autor:
Kenneth D. Tew, Christopher J. Pazoles, Woodrow J. Coker, Yefim Manevich, Joachim D. Uys, Danyelle M. Townsend, Christina L. Grek
PDF file - 5MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213f612ef4e0e1baba491e4c8d5a1e3d
https://doi.org/10.1158/0008-5472.22395422.v1
https://doi.org/10.1158/0008-5472.22395422.v1
Autor:
Kenneth D. Tew, Christopher J. Pazoles, Woodrow J. Coker, Yefim Manevich, Joachim D. Uys, Danyelle M. Townsend, Christina L. Grek
PDF file - 2.1MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374afc556a4f5fac4466ed98857d3cb8
https://doi.org/10.1158/0008-5472.22395425
https://doi.org/10.1158/0008-5472.22395425
Publikováno v:
Eur J Neurosci
Substance use disorder is a chronic relapsing disorder characterized by transitioning from acute drug reward to compulsive drug use. Despite the heavy personal and societal burden of substance use disorders, current treatments are limited and unsatis
Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis
Autor:
Michael J. Pulkoski-Gross, Agnieszka B. Bialkowska, Joachim D. Uys, Ashley J. Snider, Zdzislaw M. Szulc, Yusuf A. Hannun, Danyelle M. Townsend, Aiping Bai, Nicolas Coant, Alicja Bielawska, K. Alexa Orr-Gandy, Lina M. Obeid
Publikováno v:
Prostaglandins & Other Lipid Mediators. 130:47-56
Sphingosine-1-phosphate (S1P) is a biologically active sphingolipid metabolite which has been implicated in many diseases including cancer and inflammatory diseases. Recently, sphingosine kinase 1 (SK1), one of the isozymes which generates S1P, has b
Substance use disorders (SUDs) are major worldwide health problems, and abused drugs do not have effective pharmacotherapies to treat individuals with addiction or prevent high rates of relapse. Preclinical models of drug addiction have been develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae084b49e870c24c79ba661903483f0
https://doi.org/10.1016/b978-0-12-812202-0.00009-9
https://doi.org/10.1016/b978-0-12-812202-0.00009-9
Autor:
Basma Al Masraf, Eden Anderson, David A. Baker, Kelly Barko, Christelle Baunez, Allison R. Bechard, Howard C. Becker, Lauren N. Beloate, Rick A. Bevins, David M. Dietz, Elizabeth M. Doncheck, Andrew Eagle, Michel Engeln, Stephanie L. Foster, T. Chase Francis, Rita A. Fuchs, Amy M. Gancarz, Olivier George, Ethan J. Hansen, Matthew Hearing, Evan Hess, Jessica A. Higginbotham, Bruce T. Hope, Peter W. Kalivas, Courtney E. King, Lori A. Knackstedt, Mary Kay Lobo, Ryan W. Logan, Aric Madayag, John R. Mantsch, Jacqueline F. McGinty, Natalie S. McGuier, Patrick J. Mulholland, Jennifer E. Murray, Casey E. O’Neill, Yann Pelloux, Matthew T. Rich, A.J. Robison, Joseph A. Seggio, Micah A. Shelton, Brady M. Thompson, Mary M. Torregrossa, Joachim D. Uys, David Weinshenker, Craig T. Werner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44926833133b251c99a4c5e1d6668d32
https://doi.org/10.1016/b978-0-12-812202-0.09992-9
https://doi.org/10.1016/b978-0-12-812202-0.09992-9
Autor:
J Daniel Obray, Scott C. Steffensen, Joachim D. Uys, Jordan T. Yorgason, David M. Hedges, Frederick P. Bellinger, Vajira K. Weerasekara, Eun Young Jang
Methamphetamine (METH) is a drug with a high addictive potential that is widely abused across the world. Although it is known that METH dysregulates both dopamine transmission and dopamine reuptake, the specific mechanism of action remains obscure. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e66ab21f1644c6083d094ba510627a4
https://europepmc.org/articles/PMC5916361/
https://europepmc.org/articles/PMC5916361/