Výsledky vyhledávání - "Joachim Alhbeck"

Akademický článek

ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning

Autor: Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

In mice, reactivation of neurons that express cFos during fear conditioning induces a behavioural response. Here the authors show that cFos expression in mouse dentate gyrus shifts every day to different neurons, even during highly consistent spatial

Externí odkaz: https://doaj.org/article/3533e982510d493eb9e861a533fcd010

Zobrazit plný text záznamu

ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning

Publikováno v: Nature communications. 13(1)

Mice display signs of fear when neurons that express cFos during fear conditioning are artificially reactivated. This finding gave rise to the notion that cFos marks neurons that encode specific memories. Here we show that cFos expression patterns in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90aec1ec5ff32704e2c6edeb478cf412
https://pubmed.ncbi.nlm.nih.gov/36289226

Zobrazit plný text záznamu

cFos ensembles in the dentate gyrus rapidly segregate over time and do not form a stable map of space

Transgenic cFos reporter mice are used to identify and manipulate neurons that store contextual information during fear learning. It is not clear, however, how spatial information acquired over several training days is integrated in the hippocampus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef4d61ecb94becc34c8e82cf5c8ff43c
https://doi.org/10.1101/2020.08.29.273391

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání