Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joachim, Stephanie Christine"'
Autor:
Hurst, José, Mueller‐Buehl, Ana Maria, Hofmann, Lisa, Kuehn, Sandra, Herms, Fenja, Schnichels, Sven, Joachim, Stephanie Christine
Publikováno v:
Journal of Cellular and Molecular Medicine
Nitrite oxide plays an important role in the pathogenesis of various retinal diseases, especially when hypoxic processes are involved. This degeneration can be simulated by incubating porcine retinal explants with CoCl2. Here, the therapeutic potenti
Autor:
Hunziker, Daniel, Reinehr, Sabrina (Dr. rer. nat.), Palmhof, Marina (Dr. rer. nat.), Wagner, Natalie (M. Sc.), Biniasch, Thomas Martin (Dr. med.), Stute, Gesa (B.Sc.), Mattei, Patrizio, Schmitz, Petra, DiGiorgio, Patrick, Hert, Jérôme, Rudolph, Markus G., Benz, Jörg, Stihle, Martine, Gsell, Bernard, Müller, Stephan, Gasser, Rodolfo, Schonhoven, Nina, Ullmer, Christoph, Joachim, Stephanie Christine (Prof. Dr. med.)
The autotaxin-lysophosphatidic acid (ATX-LPA) signaling pathway plays a role in a variety of autoimmune diseases, such as rheumatoid arthritis or neurodegeneration. A link to the pathogenesis of glaucoma is suggested by an overactive ATX-LPA axis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::7cfda27e15c196dc1a7750d7c72e77ba
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/8675/Supplement.docx
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/8675/Supplement.docx
Autor:
Müller-Bühl, Ana M. (Dr, med.), Bühner, Torsten (Dr. med. vet), Pfarrer, Christiane (Prof. Dr.), Deppe, Leonie (B. Sc.), Peters, Laura, Dick, Burkhard (Prof. Dr. med.), Joachim, Stephanie Christine (Prof. Dr. med.)
Publikováno v:
Cells, Vol 10, Iss 3575, p 3575 (2021)
Considering the fact that many retinal diseases are yet to be cured, the pathomechanisms of these multifactorial diseases need to be investigated in more detail. Among others, oxidative stress and hypoxia are pathomechanisms that take place in retina
Autor:
Reinehr, Sabrina (Dr. rer. nat.), Dörner, Johanna Dorothea (Dr. med.), Müller-Bühl, Ana M. (Dr, med.), Koch, Dennis, Fuchshofer, Rudolf (Dr. rer. nat.), Dick, Burkhard (Prof. Dr. med.), Joachim, Stephanie Christine (Prof. Dr. med.)
Glaucoma is a complex neurodegenerative disease leading to a loss of retinal ganglion cells (RGCs) and optic nerve axons. An activation of the complement system seems to contribute to cell loss in this disease. Hence, we investigated a possible initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::5d4e21ea1bc746eb42ec7c42ed23fa0e
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/8997/JoachimStephanie9.pdf
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/8997/JoachimStephanie9.pdf
Autor:
Wiemann, Susanne (M. Sc.), Yousf, Aisha (M. Sc.), Joachim, Stephanie Christine (Prof. Dr. med.), Peters, Carolin, Müller-Bühl, Ana M. (Dr, med.), Wagner, Natalie (M. Sc.), Reinhard, Jacqueline (Dr. rer. nat.)
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Retinal ischemia is a common pathomechanism in various eye diseases. Recently, evidence accumulated suggesting that the extracellular matrix (ECM) glycoprotein tenascin-C (Tnc) plays a key role in ischemic degeneration. However, the possible function
Autor:
Grotegut, Pia (Dr. rer. nat.), Perumal, Natarajan (Dr. rer. nat.), Kühn, Sandra (Dr. rer. nat.), Smit, Andreas, Dick, Burkhard (Prof. Dr. med.), Grus, Franz-Hermann (Prof. Dr. med.), Joachim, Stephanie Christine (Prof. Dr. med.)
\(\bf Background:\) Previous studies noted that intravitreal injection of S100B triggered a glaucoma-like degeneration of retina and optic nerve as well as microglia activation after 14 days. The precise role of microglia in our intravitreal S100B mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::4c62851bba487c28e49a85d05cadd83d
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/9562
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/9562
Autor:
Reinhard, Jacqueline (Dr. rer. nat.), Wagner, Natalie (M. Sc.), Krämer, Miriam (M. Sc.), Jarocki, Marvin Heiko (Dr. rer. nat.), Joachim, Stephanie Christine (Prof. Dr. med.), Dick, Burkhard (Prof. Dr. med.), Faissner, Andreas (Prof. Dr.), Kakkassery, Vinodh (Dr. med.)
Retinoblastoma (RB) represents the most common malignant childhood eye tumor worldwide. Several studies indicate that the extracellular matrix (ECM) plays a crucial role in tumor growth and metastasis. Moreover, recent studies indicate that the ECM c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::a74d8a0245171470c47bb1f734bfcec9
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7803/ReinhardJacqueline1.pdf
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7803/ReinhardJacqueline1.pdf
Autor:
Grotegut, Pia (Dr. rer. nat.), Kühn, Sandra (Dr. rer. nat.), Dick, Burkhard (Prof. Dr. med.), Joachim, Stephanie Christine (Prof. Dr. med.)
Heat shock protein 27 (HSP27) is commonly involved in cellular stress. Increased levels of HSP27 as well as autoantibodies against this protein were previously detected in glaucoma patients. Moreover, systemic immunization with HSP27 induced glaucoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::9afd1fec2ede22466c68df5c4b4d7d7f
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7833/JoachimStephanie5.pdf
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7833/JoachimStephanie5.pdf
Autor:
Tsai, Teresa (Dr. rer. nat.), Reinehr, Sabrina (Dr. rer. nat.), Maliha, Ana Maria (M. Sc.), Joachim, Stephanie Christine (Prof. Dr. med.)
The underlying pathomechanisms for glaucoma, one of the most common causes of blindness worldwide, are still not identified. In addition to increased intraocular pressure (IOP), oxidative stress, excitotoxicity, and immunological processes seem to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::8e79ca4c616637db52cce17cd853979e
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7278
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7278
Autor:
Reinehr, Sabrina (Dr. rer. nat.), Reinhard, Jacqueline (Dr. rer. nat.), Wiemann, Susanne (M. Sc.), Hesse, Karoline, Voss, Christina, Gandej, Marcel, Dick, Burkhard (Prof. Dr. med.), Faissner, Andreas (Prof. Dr.), Joachim, Stephanie Christine (Prof. Dr. med.)
Studies have suggested an involvement of the immune system in glaucoma. Hence, a rat experimental autoimmune glaucoma model (EAG) was developed to investigate the role of the immune response. Here, we transferred this model into mice. Either 0.8 mg/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::5b90673327280a6dfae30c699ab833f3
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7100
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7100