Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Joachim, Heberle"'
Autor:
Guillaume Gotthard, Sandra Mous, Tobias Weinert, Raiza Nara Antonelli Maia, Daniel James, Florian Dworkowski, Dardan Gashi, Antonia Furrer, Dmitry Ozerov, Ezequiel Panepucci, Meitian Wang, Gebhard F. X. Schertler, Joachim Heberle, Joerg Standfuss, Przemyslaw Nogly
Publikováno v:
IUCrJ, Vol 11, Iss 5, Pp 792-808 (2024)
Light–oxygen–voltage (LOV) domains are small photosensory flavoprotein modules that allow the conversion of external stimuli (sunlight) into intracellular signals responsible for various cell behaviors (e.g. phototropism and chloroplast relocatio
Externí odkaz:
https://doaj.org/article/0487f96a71db49698c8ff3e32bc949bf
Autor:
Mina Aleksanyan, Andrea Grafmüller, Fucsia Crea, Vasil N. Georgiev, Naresh Yandrapalli, Stephan Block, Joachim Heberle, Rumiana Dimova
Publikováno v:
Advanced Science, Vol 10, Iss 31, Pp n/a-n/a (2023)
Abstract Light can effectively interrogate biological systems in a reversible and physiologically compatible manner with high spatiotemporal precision. Understanding the biophysics of photo‐induced processes in bio‐systems is crucial for achievin
Externí odkaz:
https://doaj.org/article/5a4ba803cce04c4180b0cfe2b7284e18
Autor:
Katerina Kanevche, David J. Burr, Dennis J. Nürnberg, Pascal K. Hass, Andreas Elsaesser, Joachim Heberle
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Kanevche and colleagues present a combined imaging method employing scattering-type scanning near-field optical microscopy and Fourier-transform infrared spectroscopy to visualize the internal structures of cells. Demonstrating their method on eukary
Externí odkaz:
https://doaj.org/article/e36f962a5a5b4664be5fd741df2e0e5a
Autor:
Kenichi Ataka, Axel Baumann, Jheng-Liang Chen, Aoife Redlich, Joachim Heberle, Ramona Schlesinger
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The translocon-unassisted folding process of transmembrane domains of the microbial rhodopsins sensory rhodopsin I (HsSRI) and II (HsSRII), channelrhodopsin II (CrChR2), and bacteriorhodopsin (HsBR) during cell-free expression has been investigated b
Externí odkaz:
https://doaj.org/article/4e122f03c65640c283e3b82479595cca
Autor:
Fucsia Crea, Antreas Vorkas, Aoife Redlich, Rubén Cruz, Chaowei Shi, Dirk Trauner, Adam Lange, Ramona Schlesinger, Joachim Heberle
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Optogenetics in the conventional sense, i.e. the use of engineered proteins that gain their light sensitivity from naturally abundant chromophores, represents an exciting means to trigger and control biological activity by light. As an alternate appr
Externí odkaz:
https://doaj.org/article/252058baea61487ba4001928c8af6fab
Autor:
Federico Baserga, Antreas Vorkas, Fucsia Crea, Luiz Schubert, Jheng-Liang Chen, Aoife Redlich, Mariafrancesca La Greca, Julian Storm, Sabine Oldemeyer, Kirsten Hoffmann, Ramona Schlesinger, Joachim Heberle
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
It is well known that lipids neighboring integral membrane proteins directly influence their function. The opposite effect is true as well, as membrane proteins undergo structural changes after activation and thus perturb the lipidic environment. Her
Externí odkaz:
https://doaj.org/article/83fc5add385e4b87ac5fa2629ced1454
Autor:
Mariafrancesca La Greca, Jheng-Liang Chen, Luiz Schubert, Jacek Kozuch, Tim Berneiser, Ulrich Terpitz, Joachim Heberle, Ramona Schlesinger
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Microbial rhodopsins have recently been discovered in pathogenic fungi and have been postulated to be involved in signaling during the course of an infection. Here, we report on the spectroscopic characterization of a light-driven proton pump rhodops
Externí odkaz:
https://doaj.org/article/d3846136bbf5460ba8359fa9f5053c66
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
Direct optical activation of microbial rhodopsins in deep biological tissue suffers from ineffective light delivery because visible light is strongly scattered and absorbed. NIR light has deeper tissue penetration, but NIR-activation requires a trans
Externí odkaz:
https://doaj.org/article/fc07b089b1d34258a922c7a3d7ee2b6f
Autor:
Federico Baserga, Jovan Dragelj, Jacek Kozuch, Hendrik Mohrmann, Ernst-Walter Knapp, Sven T. Stripp, Joachim Heberle
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Cytochrome c oxidase (CcO) is a transmembrane protein complex that reduces molecular oxygen to water while translocating protons across the mitochondrial membrane. Changes in the redox states of its cofactors trigger both O2 reduction and vectorial p
Externí odkaz:
https://doaj.org/article/e864d34714b64a06af9763fda6cbeb98
Autor:
Gabriela Nass Kovacs, Jacques-Philippe Colletier, Marie Luise Grünbein, Yang Yang, Till Stensitzki, Alexander Batyuk, Sergio Carbajo, R. Bruce Doak, David Ehrenberg, Lutz Foucar, Raphael Gasper, Alexander Gorel, Mario Hilpert, Marco Kloos, Jason E. Koglin, Jochen Reinstein, Christopher M. Roome, Ramona Schlesinger, Matthew Seaberg, Robert L. Shoeman, Miriam Stricker, Sébastien Boutet, Stefan Haacke, Joachim Heberle, Karsten Heyne, Tatiana Domratcheva, Thomas R. M. Barends, Ilme Schlichting
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Bacteriorhodopsin (bR) is a light-driven proton pump. Here the authors combine time-resolved crystallography at a free-electron laser, ultrafast spectroscopy and quantum chemistry to study the structural changes following multiphoton photoexcitation
Externí odkaz:
https://doaj.org/article/a086ef8dd24c43efbb5f1448e1c960cf