Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Joachim, Füllekrug"'
Acyl‐CoA synthetase expression in human skeletal muscle is reduced in obesity and insulin resistance
Autor:
Margarete Poppelreuther, Anne‐Marie Lundsgaard, Pernille Mensberg, Kim Sjøberg, Tina Vilsbøll, Bente Kiens, Joachim Füllekrug
Publikováno v:
Physiological Reports, Vol 11, Iss 18, Pp n/a-n/a (2023)
Abstract Upon intramuscular entry, fatty acids are converted to amphiphatic fatty acyl‐CoAs by action of the acyl‐CoA synthetase (ACS) enzymes. While it has been reported that insulin resistant skeletal muscle shows an accumulation of fatty acyl
Externí odkaz:
https://doaj.org/article/6a0a4a12c6464808912a29c001f6bcab
Autor:
Tarik Exner, Carlo A. Beretta, Qi Gao, Cassian Afting, Inés Romero-Brey, Ralf Bartenschlager, Leonard Fehring, Margarete Poppelreuther, Joachim Füllekrug
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1333-1344 (2019)
Lipid droplets (LDs) are ubiquitous and highly dynamic subcellular organelles required for the storage of neutral lipids. LD number and size distribution are key parameters affected not only by nutrient supply but also by lipotoxic stress and metabol
Externí odkaz:
https://doaj.org/article/f5006bee3dbd4c18b2319d5e0b6adb5d
Autor:
Margarete Poppelreuther, Berenice Rudolph, Chen Du, Regina Großmann, Melanie Becker, Christoph Thiele, Robert Ehehalt, Joachim Füllekrug
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 888-900 (2012)
Cytosolic lipid droplets (LDs) are storage organelles for neutral lipids derived from endogenous metabolism. Acyl-CoA synthetase family proteins are essential enzymes in this biosynthetic pathway, contributing activated fatty acids. Fluorescence micr
Externí odkaz:
https://doaj.org/article/ef17041411494197a65ab3b10d8d7a2c
Publikováno v:
International Journal of Medical Sciences, Vol 8, Iss 7, Pp 599-614 (2011)
Background: Understanding the mechanisms of long chain fatty acid (LCFA) uptake in hepatic cells is of high medical importance to treat and to prevent fatty liver disease (FLD). ACSs (Acyl-CoA synthetases) are a family of enzymes that catalyze the es
Externí odkaz:
https://doaj.org/article/90518090e00c46adaa4bd69f9e270b1b
Autor:
Leonard Fehring, Inés Romero-Brey, Cassian Afting, Margarete Poppelreuther, Ralf Bartenschlager, Joachim Füllekrug, Tarik Exner, Qi Gao, Carlo A. Beretta
Publikováno v:
J Lipid Res
Journal of Lipid Research, Vol 60, Iss 7, Pp 1333-1344 (2019)
Journal of Lipid Research, Vol 60, Iss 7, Pp 1333-1344 (2019)
Lipid droplets (LDs) are ubiquitous and highly dynamic subcellular organelles required for the storage of neutral lipids. LD number and size distribution are key parameters affected not only by nutrient supply but also by lipotoxic stress and metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e0c5f169aefcd076838e1d6e0188ff
https://doi.org/10.1194/jlr.d092841
https://doi.org/10.1194/jlr.d092841
Autor:
Joachim Füllekrug, Ghalia Al-Kasbi, Mohammed Mohammed, Nadia Al-Hashmi, Uta Merle, Svenja Sliwinski, Cassian Afting, Khalid Al-Thihli, Khalsa Al-Kharusi, Almundher Al-Maawali, Naema Al‐Shibli, Khoula Al-Said
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1065fe70b9efc1b49c1afb960f4d5f55
https://doi.org/10.1111/cge.13883/v2/response1
https://doi.org/10.1111/cge.13883/v2/response1
Autor:
Nadia Al-Hashmi, Naema Al Shibli, Svenja Sliwinski, Khoula Al-Said, Joachim Füllekrug, Ghalia Al-Kasbi, Uta Merle, Mohammed Mohammed, Almundher Al-Maawali, Cassian Afting, Khalid Al-Thihli, Khalsa Al-Kharusi
Publikováno v:
Clinical geneticsREFERENCES. 99(3)
Failure to thrive (FTT) causes significant morbidity, often without clear etiologies. Six individuals of a large consanguineous family presented in the neonatal period with recurrent vomiting and diarrhea, leading to severe FTT. Standard diagnostic w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33c15f89db5f996cdd9ef25dc78182d
https://pubmed.ncbi.nlm.nih.gov/33191500
https://pubmed.ncbi.nlm.nih.gov/33191500
Publikováno v:
Seminars in celldevelopmental biology. 108
Lipid droplets (LDs) are now recognized as omnipresent and dynamic subcellular organelles of amazing morphological and functional diversity. Beyond the obvious benefit of having molecules full of chemical energy stored in a dedicated structural entit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842e19604a427416bd551a684a68cb26
https://pubmed.ncbi.nlm.nih.gov/32636101
https://pubmed.ncbi.nlm.nih.gov/32636101
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45087 (2012)
Long chain acyl-CoA synthetases are essential enzymes of lipid metabolism, and have also been implicated in the cellular uptake of fatty acids. It is controversial if some or all of these enzymes have an additional function as fatty acid transporters
Externí odkaz:
https://doaj.org/article/b31fac1c3a5e439ebf69028547021563
Autor:
Jacob Jeppesen, Andreas B Jordy, Kim A Sjøberg, Joachim Füllekrug, Andreas Stahl, Lars Nybo, Bente Kiens
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29391 (2012)
FATP1 and FATP4 appear to be important for the cellular uptake and handling of long chain fatty acids (LCFA). These findings were obtained from loss- or gain of function models. However, reports on FATP1 and FATP4 in human skeletal muscle are limited
Externí odkaz:
https://doaj.org/article/3d360945d94d48e69993b8bad202efed