Zobrazeno 1 - 5
of 5
pro vyhledávání: '"João T. S. Coimbra"'
Autor:
João T. S. Coimbra, Antoine Gissler, Emiel Nitor, Kiana Rostamipour, Ana V. Cunha, Maria J. Ramos, Pedro A. Fernandes
Publikováno v:
JACS Au, Vol 4, Iss 11, Pp 4295-4306 (2024)
Externí odkaz:
https://doaj.org/article/9cc33b4283574138bcc54e21ffd71ac3
Autor:
How Chee Ong, João T. S. Coimbra, Maria J. Ramos, Bengang Xing, Pedro A. Fernandes, Felipe García
Publikováno v:
Scopus
Fundación para el Fomento en Asturias de la Investigación Científica Aplicada y la Tecnología (FICYT) through the Margarita Salas Senior Program (AYUD/2021/59709) and the Ministerio de Ciencia e Innovación through the project PID2021-127407NB-I0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7930d5cfd3eb8f55fbba4301644069f
http://hdl.handle.net/10651/68591
http://hdl.handle.net/10651/68591
Publikováno v:
Chemistry – A European Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d583809fd49e8cee2aedd19205eb1c3
https://doi.org/10.1002/chem.202202001
https://doi.org/10.1002/chem.202202001
Autor:
How Chee Ong, João T. S. Coimbra, Maria J. Ramos, Bengang Xing, Pedro A. Fernandes, Felipe Garcia
Mitochondrial targeting represents an attractive strategy for treating metabolic, degenerative and hyperproliferative diseases, since this organelle plays key roles in essential cellular functions. Triphenylphosphonium (TPP+) moieties – the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bef6d7d12862a5fb6fbc14dde737e085
https://doi.org/10.26434/chemrxiv-2022-xhrd8
https://doi.org/10.26434/chemrxiv-2022-xhrd8
Autor:
How Chee, Ong, João T S, Coimbra, Germain, Kwek, Maria J, Ramos, Bengang, Xing, Pedro A, Fernandes, Felipe, García
Publikováno v:
RSC Chemical Biology
Triphenylphosphonium (TPP+) moieties are commonly conjugated to drug molecules to confer mitochondrial selectivity due to their positive charge and high lipophilicity. Although optimisation of lipophilicity can be achieved by modifying the length of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82114d68a4f57057d9875b47d27b63d4
https://pubmed.ncbi.nlm.nih.gov/34977579
https://pubmed.ncbi.nlm.nih.gov/34977579