Zobrazeno 1 - 10
of 148
pro vyhledávání: '"JoAnne Wilson"'
Autor:
Thomas G. Hayhow, Beth Williamson, Mandy Lawson, Natalie Cureton, Erin L. Braybrooke, Andrew Campbell, Rodrigo J. Carbajo, Azadeh Cheraghchi-Bashi, Elisabetta Chiarparin, Coura R. Diène, Charlene Fallan, David I. Fisher, Frederick W. Goldberg, Lorna Hopcroft, Philip Hopcroft, Anne Jackson, Jason G. Kettle, Teresa Klinowska, Ulrike Künzel, Gillian Lamont, Hilary J. Lewis, Gareth Maglennon, Scott Martin, Pablo Morentin Gutierrez, Christopher J. Morrow, Myria Nikolaou, J. Willem M. Nissink, Patrick O’Shea, Radoslaw Polanski, Markus Schade, James S. Scott, Aaron Smith, Judith Weber, Joanne Wilson, Bin Yang, Claire Crafter
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Targeting the estrogen receptor alpha (ERα) pathway is validated in the clinic as an effective means to treat ER+ breast cancers. Here we present the development of a VHL-targeting and orally bioavailable proteolysis-targeting chimera (PROT
Externí odkaz:
https://doaj.org/article/ec006f9560824ea494be6041bb1eeb60
Autor:
Josephine S. F. Chow, Neil Boudville, Yeoungjee Cho, Suetonia Palmer, Elaine M. Pascoe, Carmel M. Hawley, Donna M. Reidlinger, Laura E. Hickey, Ruth Stastny, Andrea Valks, Liza Vergara, Ramya Movva, Charani Kiriwandeniya, Hayley Candler, Gabor Mihala, Bernadette Buisman, Keri-Lu Equinox, Ana E. Figueiredo, Trudi Fuge, Kirsten Howard, Martin Howell, Allison Jaure, Matthew D. Jose, Anna Lee, Susana S. Miguel, Jo-anne Moodie, Thu T. Nguyen, Geraldine Pinlac, Annie Reynolds, Walaa W. M. Saweirs, Genevieve Z. Steiner-Lim, Bronwen TeWhare, Melinda Tomlins, Megan Upjohn, David Voss, Rachael C. Walker, Joanne Wilson, David W. Johnson
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Peritoneal dialysis (PD)-related infections, such as peritonitis, exit site, and tunnel infections, substantially impair the sustainability of PD. Accordingly, PD-related infection is the top-priority research outcome for patients
Externí odkaz:
https://doaj.org/article/1579c83aac2441a5936bcb89799e605f
Autor:
Thomas Hyunwoo Cho, Patrick C. K. Ng, Melissa J. Lefebvre, Arlene Desjarlais, Dennis McCann, Blair Waldvogel, Marcello Tonelli, Amit X. Garg, JoAnne Wilson, Monica Beaulieu, Judith Marin, Cali Orsulak, Melanie Talson, Monica Sharma, Jordanne Feldberg, Clara Bohm, Marisa Battistella
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Background: Deprescribing is a patient-centered solution to reducing polypharmacy in patients on hemodialysis (HD). In a deprescribing pilot study, patients were hesitant to participate due to limited understanding of their own medications and their
Externí odkaz:
https://doaj.org/article/ab8bd64750fe4cdcab081ed600f8a7d5
Autor:
Jacqueline H. L. Fok, Antonio Ramos-Montoya, Mercedes Vazquez-Chantada, Paul W. G. Wijnhoven, Valeria Follia, Neil James, Paul M. Farrington, Ankur Karmokar, Sophie E. Willis, Jonathan Cairns, Jenni Nikkilä, David Beattie, Gillian M. Lamont, M. Raymond V. Finlay, Joanne Wilson, Aaron Smith, Lenka Oplustil O’Connor, Stephanie Ling, Stephen E. Fawell, Mark J. O’Connor, Simon J. Hollingsworth, Emma Dean, Frederick W. Goldberg, Barry R. Davies, Elaine B. Cadogan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
DNA-dependent protein kinase (DNA-PK) plays a major role in the DNA damage response upon double-strand break formation. Here, the authors show that the DNA-PK inhibitor AZD7648, enhances the activity of radiotherapy, chemotherapy and the PARP inhibit
Externí odkaz:
https://doaj.org/article/7547983126794fc0a17cf1c4d462a298
Autor:
Giulia Dellavedova, Alessandra Decio, Laura Formenti, Mark R. Albertella, Joanne Wilson, Anna D. Staniszewska, Elisabetta Leo, Raffaella Giavazzi, Carmen Ghilardi, Maria Rosa Bani
Publikováno v:
Cancer Research Communications. 3:489-500
PARP inhibitors (PARPi) have changed the management of patients with ovarian cancer and their effectiveness has been demonstrated especially in homologous recombination repair–deficient tumors. These first-generation drugs target PARP1, but also PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ce5d67724488afd71bae4eaaefa478
https://doi.org/10.1158/2767-9764.crc-22-0423
https://doi.org/10.1158/2767-9764.crc-22-0423
Autor:
Kristoffer Valerie, Stephen T. Durant, Martin Pass, Kan Chen, Yingchun Wang, Tianwei Zhang, Li Zheng, Ian P. Barrett, Aaron Smith, Joanne Wilson, Nicola Colclough, Jason Kettle, Sebastien L. Degorce, Bernard Barlaam, Nitai Mukhopadhyay, Jason M. Beckta, Jenna Kahn, Laura Biddlestone-Thorpe, Nicholas C.K. Valerie, Amrita Sule, Thomas A. Hunt, Kurt G. Pike, Alan Lau, Jennifer Vincent, Bhavika Patel, Andrew G. Thomason, Antonio Garcia-Trinidad, Lucy C. Riches, Elaine B. Cadogan, Paul Farrington, Rajesh Odedra, Victoria Sheridan, Gareth Hughes, Syed F. Ahmad, Jasmine Allen, Jeremy Karlin
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ee016739d4d6ff0e2ec657589845d
https://doi.org/10.1158/1535-7163.22504764.v1
https://doi.org/10.1158/1535-7163.22504764.v1
Autor:
Kristoffer Valerie, Stephen T. Durant, Martin Pass, Kan Chen, Yingchun Wang, Tianwei Zhang, Li Zheng, Ian P. Barrett, Aaron Smith, Joanne Wilson, Nicola Colclough, Jason Kettle, Sebastien L. Degorce, Bernard Barlaam, Nitai Mukhopadhyay, Jason M. Beckta, Jenna Kahn, Laura Biddlestone-Thorpe, Nicholas C.K. Valerie, Amrita Sule, Thomas A. Hunt, Kurt G. Pike, Alan Lau, Jennifer Vincent, Bhavika Patel, Andrew G. Thomason, Antonio Garcia-Trinidad, Lucy C. Riches, Elaine B. Cadogan, Paul Farrington, Rajesh Odedra, Victoria Sheridan, Gareth Hughes, Syed F. Ahmad, Jasmine Allen, Jeremy Karlin
U87/Centrin2-EGFP/H2B-mCherry/puro cells were seeded on dishes with cover slip bottoms, treated with AZ32 (3 uM), and irradiated (5 Gy). Time-lapse videos were recorded intermittently (every 7 min) over 16 hrs. Treatment results in 11% aberrant mitos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d9bad2471d6722b3a914316ea1d053
https://doi.org/10.1158/1535-7163.22504755
https://doi.org/10.1158/1535-7163.22504755
Autor:
Paul D. Smith, J. Elizabeth Pease, Sabina C. Cosulich, Iain Simpson, Richard A. Ward, Clifford D. Jones, Stephen E. Fawell, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Claire Rooney, Martine P. Roudier, Sophie E. Willis, Philip Hopcroft, Michael Tonge, Karen Roberts, Joanne Wilson, Aaron Smith, Nicola Lindsay, Francis D. Gibbons, Katarzyna Falenta, Sigourney Bell, Paul Farrington, Lyndsey Hanson, Pei Zhang, Oona Delpuech, Linda C. Sandin, David Robinson, Emma J. Davies, Vikki Flemington
Primers used for targeted gene profiling on selected RAS/MAPK pathway genes either on Fluidigm or by qRT-PCR on Roche Lightcycler 480
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24be1d38b84bbeb9fe19955e7de25d2b
https://doi.org/10.1158/1535-7163.22521541
https://doi.org/10.1158/1535-7163.22521541
Autor:
Paul D. Smith, J. Elizabeth Pease, Sabina C. Cosulich, Iain Simpson, Richard A. Ward, Clifford D. Jones, Stephen E. Fawell, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Claire Rooney, Martine P. Roudier, Sophie E. Willis, Philip Hopcroft, Michael Tonge, Karen Roberts, Joanne Wilson, Aaron Smith, Nicola Lindsay, Francis D. Gibbons, Katarzyna Falenta, Sigourney Bell, Paul Farrington, Lyndsey Hanson, Pei Zhang, Oona Delpuech, Linda C. Sandin, David Robinson, Emma J. Davies, Vikki Flemington
Supplementary Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8cb1ae292b59622591433bfe72565e
https://doi.org/10.1158/1535-7163.22521556
https://doi.org/10.1158/1535-7163.22521556
Autor:
Maria Rosa Bani, Raffaella Giavazzi, Elaine B. Cadogan, Carmen Ghilardi, Joanne Wilson, Hana Baakza, Massimo Russo, Giovanna Chiorino, Neil James, Antonio Ramos-Montoya, Giulia Dellavedova, Alessia Anastasia
Supplementary Data from The DNA-PK Inhibitor AZD7648 Sensitizes Patient-Derived Ovarian Cancer Xenografts to Pegylated Liposomal Doxorubicin and Olaparib Preventing Abdominal Metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef963a27f8df98bd291fe201e5ba3aa
https://doi.org/10.1158/1535-7163.22522287.v1
https://doi.org/10.1158/1535-7163.22522287.v1