Zobrazeno 1 - 10
of 10
pro vyhledávání: '"JoAnne Dzink-Fox"'
Autor:
Stephanie E Woods, Mia T Lieberman, Francois Lebreton, Elise Trowel, César de la Fuente-Núñez, Joanne Dzink-Fox, Michael S Gilmore, James G Fox
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169293 (2017)
Nonhuman primates are commonly used for cognitive neuroscience research and often surgically implanted with cephalic recording chambers for electrophysiological recording. Aerobic bacterial cultures from 25 macaques identified 72 bacterial isolates,
Externí odkaz:
https://doaj.org/article/02cb0a64142642ffb269f2c2437ada80
Autor:
Elise M. Trowel, Cesar de la Fuente-Nunez, James G. Fox, Stephanie E. Woods, Francois Lebreton, Joanne Dzink-Fox, Michael S. Gilmore, Mia T Lieberman
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169293 (2017)
PLoS ONE
PLoS
PLoS ONE
PLoS
Nonhuman primates are commonly used for cognitive neuroscience research and often surgically implanted with cephalic recording chambers for electrophysiological recording. Aerobic bacterial cultures from 25 macaques identified 72 bacterial isolates,
Autor:
JoAnne Dzink-Fox, Jason T. Brewer, Esther K. Schmitt, Karl Dean, Matthew J. LaMarche, Stacey Tiamfook, Gabe Gamber, Zachary Robinson, Jennifer A. Leeds, Michael A. Patane, Deborah Palestrant, Colin Osborne, Franco Lombardo, Akash K. Jain, David McKenney, Jian Ding, Lewis Whitehead, Philipp Krastel, Elin M. Rann, Travis Stams, Donghui Yu, Ryan Kerrigan, Georg Neckermann, Kwangho Lee
Publikováno v:
Journal of medicinal chemistry. 59(14)
Synthetic studies of the antimicrobial secondary metabolite thiomuracin A (1) provided access to analogues in the Northern region (C2–C10). Selective hydrolysis of the C10 amide of lead compound 2 and subsequent derivatization led to novel carbon-
Autor:
Georg Neckermann, Philipp Krastel, JoAnne Dzink-Fox, Jennifer A. Leeds, Donghui Yu, Stacey Tiamfook, Deborah Palestrant, Elin M. Rann, Eric Gangl, Michael A. Patane, Matthew J. LaMarche
Publikováno v:
Journal of medicinal chemistry. 55(15)
Synthetic studies of the antimicrobial secondary metabolite thiomuracin A (1) were initiated to improve chemical stability and physicochemical properties. Functional group modifications of 1 included removing the C2–C7 side chain, derivatizing the
Publikováno v:
Antimicrobial agents and chemotherapy. 56(8)
LFF571 is a novel semisynthetic thiopeptide and potent inhibitor of Gram-positive bacteria. We report that the antibacterial activity of LFF571 against Clostridium difficile is due to inhibition of translation. Single-step mutants of C. difficile wit
Autor:
Qingming Zhu, Bushell Simon, Stacey Tiamfook, JoAnne Dzink-Fox, Michael A. Patane, Jason T. Brewer, Deborah Palestrant, Elin M. Rann, Matthew J. LaMarche, Meena Sachdeva, Anna Trzasko, Lewis Whitehead, Jennifer A. Leeds, Steve Mullin, Janetta Dewhurst, Lac Lee, Wanlin Yan, David McKenney, Gabriel G. Gamber, Jian Ding, Aregahegn Yifru, Adam Amaral, Jian Shao, Donghui Yu, Gejing Deng, Kwangho Lee, Troy Lister, Colin P. Osborne, Akash Jain
Publikováno v:
Journal of medicinal chemistry. 55(5)
Clostridium difficile (C. difficile) is a Gram positive, anaerobic bacterium that infects the lumen of the large intestine and produces toxins. This results in a range of syndromes from mild diarrhea to severe toxic megacolon and death. Alarmingly, t
Autor:
Jennifer A. Leeds, Eric Gangl, Georg Neckermann, Jason T. Brewer, Julie Goldovitz, JoAnne Dzink-Fox, Bushell Simon, Akash Jain, Stacey Tiamfook, Deborah Palestrant, Michael A. Patane, Lewis Whitehead, Elin M. Rann, Steve Mullin, Colin Osborne, Matthew J. LaMarche, Kerri Amaral, Janetta Dewhurst, Jian Shao, Donghui Yu, Meena Sachdeva
Publikováno v:
Journal of medicinal chemistry. 54(23)
4-Aminothiazolyl analogues of the antibiotic natural product GE2270 A (1) were designed, synthesized, and optimized for their activity against Gram positive bacterial infections. Optimization efforts focused on improving the physicochemical propertie
Autor:
Karl Gunderson, Elin M. Rann, JoAnne Dzink-Fox, Stacey Tiamfook, Philipp Krastel, Matthew J. LaMarche, Jennifer A. Leeds, Klaus Memmert, Michael A. Patane, Bing Wang, Esther K. Schmitt
Publikováno v:
Journal of medicinal chemistry. 54(7)
4-Aminothiazolyl analogues of the antibacterial natural product GE2270 A (1) were designed, synthesized, and evaluated for gram positive bacteria growth inhibition. The aminothiazole-based chemical template was evaluated for chemical stability, and i
Autor:
Matthew J. LaMarche, Jennifer A. Leeds, JoAnne Dzink-Fox, Michael Patane, Steve Mullin, Elin M. Rann, Stacey Tiamfook
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(11)
Imidazole analogs of the antibiotic natural product GE2270 A (1) were designed, synthesized, and evaluated for Gram positive bacteria growth inhibition. A recently reported, copper-mediated synthesis was exploited to prepare 4-thiazolyl imidazole ana
Autor:
Matthew J. LaMarche, Jennifer A. Leeds, Kerri Amaral, JasonT. Brewer, Simon M. Bushell, Janetta M. Dewhurst, JoAnne Dzink-Fox, Eric Gangl, Julie Goldovitz, Akash Jain, Steve Mullin, Georg Neckermann, Colin Osborne, Deborah Palestrant, Michael A. Patane, Elin M. Rann, Meena Sachdeva, Jian Shao, Stacey Tiamfook, Lewis Whitehead
Publikováno v:
Journal of Medicinal Chemistry; Dec2011, Vol. 54 Issue 23, p8099-8109, 11p