Zobrazeno 1 - 10
of 24
pro vyhledávání: '"JoAnne Bruno"'
Autor:
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin, Joseph Rosenbluh, Yaara Zwang, Barbara A Weir, Charlie Hatton, Elena Ivanova, Laura Macconaill, Megan Hanna, William C Hahn, Neal F Lue, Roger R Reddel, Yuchen Jiao, Kenneth Kinzler, Bert Vogelstein, Nickolas Papadopoulos, Alan K Meeker, ALT Starr Cancer Consortium
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002772 (2012)
The Alternative Lengthening of Telomeres (ALT) pathway is a telomerase-independent pathway for telomere maintenance that is active in a significant subset of human cancers and in vitro immortalized cell lines. ALT is thought to involve templated exte
Externí odkaz:
https://doaj.org/article/f6be43954a08419ba9c14310d32fca47
Publikováno v:
Contemporary Cardiology ISBN: 9783030781767
Obesity is the abnormal accumulation of fat that presents health consequences such as cardiovascular disease. Long-term observational studies from surgical weight loss and recent pharmacotherapy trials imply that weight reduction and maintenance decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1bf124fe15600ec01f77f95df0788b
https://doi.org/10.1007/978-3-030-78177-4_8
https://doi.org/10.1007/978-3-030-78177-4_8
Autor:
Joanne Bruno, Melissa Sum
Publikováno v:
Osteoporosis ISBN: 9783030839505
Nutritional and lifestyle interventions for optimizing skeletal health are key adjuncts to pharmacologic therapy in the treatment of osteopenia and osteoporosis. Sufficient calcium and vitamin D intake is critical for maintaining bone homeostasis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::727ef7588a97c8cabd2bc432f309700c
https://doi.org/10.1007/978-3-030-83951-2_2
https://doi.org/10.1007/978-3-030-83951-2_2
Autor:
Binodh DeSilva, Alexander T. Kozhich, Rong Liu, Jia Duo, Jon E. Peterson, Jonathan Haulenbeek, Donata David-brown, Lora Hamuro, Linlin Luo, Renuka Pillutla, Steven P. Piccoli, Rasa Santockyte, JoAnne Bruno, Yan J Zhang, Suk Kwok
Publikováno v:
Bioanalysis. 10:559-576
Ligand-binding assay (LBA) performance depends on quality reagents. Strategic reagent screening and characterization is critical to LBA development, optimization and validation. Application of advanced technologies expedites the reagent screening and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7606fddc05b14aaa8d001ee0ec82d4d5
https://doi.org/10.4155/bio-2017-0271
https://doi.org/10.4155/bio-2017-0271
Publikováno v:
Bioanalysis. 9:193-207
Aim: Ligand-binding assay (LBA) reagent labeling may change the binding characteristics of the reagent to its target and degrade its performance in LBAs. Results: A surface plasmon resonance (SPR) biosensor was used to evaluate the impact of the biot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e88bb9eab6c3ff1eccc14d51ab8102c
https://doi.org/10.4155/bio-2016-0204
https://doi.org/10.4155/bio-2016-0204
Publikováno v:
The Journal of Cell Biology
Sec16A is known to be required for COPII vesicle formation from the ER. Here, Bruno et al. show that, independent of its role at the ER, Sec16A is a RAB10 effector involved in the insulin-stimulated formation of specialized transport vesicles that fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35d9f47652de129e9ebb3577d1bc6ae
https://doi.org/10.1083/jcb.201509052
https://doi.org/10.1083/jcb.201509052
Autor:
Domenick J. Falcone, Joanne Bruno, Muheeb Beg, Barbara B. Kahn, João Paulo G Camporez, Melanie S Buckman, Christopher Torsitano, L Amanda Sadacca, Domenico Accili, Olivier Elemento, Gerald I. Shulman, Belén Picatoste, Timothy E. McGraw, Akanksha Verma, Gabriela Virginia Moreira, Rajesh T. Patel, Reema P. Vazirani, Kotryna Simonyte
Publikováno v:
Diabetes
Insulin controls glucose uptake into adipose and muscle cells by regulating the amount of GLUT4 in the plasma membrane. The effect of insulin is to promote the translocation of intracellular GLUT4 to the plasma membrane. The small Rab GTPase, Rab10,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a075da6d9553b7516e4372e7189b46d8
https://doi.org/10.2337/db15-1128
https://doi.org/10.2337/db15-1128
Autor:
Jennifer Wen, Rajesh T. Patel, Joanne Bruno, Muhammad Siyab Panhwar, Timothy E. McGraw, Sameer Mohammad
Publikováno v:
Molecular and Cellular Biology. 34:3618-3629
Glucose-dependent insulinotropic polypeptide (GIP), an incretin hormone secreted from gastrointestinal K cells in response to food intake, has an important role in the control of whole-body metabolism. GIP signals through activation of the GIP recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8ce75987f2f273b3fcb8612726cd5c
https://doi.org/10.1128/mcb.00256-14
https://doi.org/10.1128/mcb.00256-14
Publikováno v:
Molecular Biology of the Cell
RAB10 and RAB14 function at sequential steps of insulin-stimulated GLUT4 translocation to the plasma membrane. RAB14 functions upstream of RAB10 in GLUT4 sorting to the specialized transport vesicles, and RAB10 and its GAP protein comprise the main s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf483faa5bd2c7c6b3a710e300137a3e
http://europepmc.org/articles/PMC3744946
http://europepmc.org/articles/PMC3744946
Autor:
F. O. Goda, Timothy G. Hammond, Pierre J. Verroust, J. H. Kaysen, F. Pontillon, Eric E. Simon, Wendy C. Campbell, Joanne Bruno, Gabriel L. Navar, Vecihi Batuman, Michelle Lyles
Publikováno v:
American Journal of Physiology-Renal Physiology. 275:F246-F254
Although myeloma light chains are known to undergo receptor-mediated endocytosis in the kidney, the molecular identity of the receptor has not been characterized. We examined the interaction between cubilin (gp280) and four species of light chains is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3557ee9c13eed3bf0dee4a3e077a58b
https://doi.org/10.1152/ajprenal.1998.275.2.f246
https://doi.org/10.1152/ajprenal.1998.275.2.f246