Zobrazeno 1 - 10
of 21
pro vyhledávání: '"JoAnn M. Tufariello"'
Autor:
Yonatan K. Sapadin, Elazar Mermelstein, Robert G. Phelps, Christopher F. Basler, JoAnn M. Tufariello, Mark G. Lebwohl
Publikováno v:
Vaccines, Vol 11, Iss 2, p 438 (2023)
Lichen planus is a distinctive mucocutaneous disease with well-established clinical and histopathologic criteria. Lichenoid eruptions closely resemble lichen planus and may sometimes be indistinguishable from it. Systemic agents previously associated
Externí odkaz:
https://doaj.org/article/7cc3e09b6e974ed6928fa05782fb8457
Autor:
Erik J. Hasenoehrl, Dannah Rae Sajorda, Linda Berney-Meyer, Samantha Johnson, JoAnn M. Tufariello, Tobias Fuhrer, Gregory M. Cook, William R. Jacobs, Michael Berney
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Amino acid biosynthetic pathways are an attractive alternative to treat chronic infections such as Mycobacterium tuberculosis (Mtb). Here, the authors investigate the metabolic response to disruption of the aspartate pathway in persistent Mtb and ide
Externí odkaz:
https://doaj.org/article/9a443ee14abc47879b6eef91b9b88f3a
Autor:
JoAnn M. Tufariello, Christopher A. Kerantzas, Catherine Vilchèze, R. Brent Calder, Eric K. Nordberg, Jack A. Fischer, Travis E. Hartman, Eva Yang, Timothy Driscoll, Laura E. Cole, Robert Sebra, Shahina B. Maqbool, Alice R. Wattam, William R. Jacobs
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Mycobacterium haemophilum is an emerging pathogen associated with a variety of clinical syndromes, most commonly skin infections in immunocompromised individuals. M. haemophilum exhibits a unique requirement for iron supplementation to suppo
Externí odkaz:
https://doaj.org/article/90a51ee400054f14b7349d432b7286d1
Autor:
JoAnn M. Tufariello, Adel A. Malek, Catherine Vilchèze, Laura E. Cole, Hannah K. Ratner, Pablo A. González, Paras Jain, Graham F. Hatfull, Michelle H. Larsen, William R. Jacobs
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Genetic engineering has contributed greatly to our understanding of Mycobacterium tuberculosis biology and has facilitated antimycobacterial and vaccine development. However, methods to generate M. tuberculosis deletion mutants remain labor-
Externí odkaz:
https://doaj.org/article/1268cf3ded4a4c76a1dc124fd7328d8a
Autor:
Paras Jain, Tsungda Hsu, Masayoshi Arai, Karolin Biermann, David S. Thaler, Andrew Nguyen, Pablo A. González, Joann M. Tufariello, Jordan Kriakov, Bing Chen, Michelle H. Larsen, William R. Jacobs
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Specialized transduction has proven to be useful for generating deletion mutants in most mycobacteria, including virulent Mycobacterium tuberculosis. We have improved this system by developing (i) a single-step strategy for the construction
Externí odkaz:
https://doaj.org/article/c26cd4668a5142cca824b53be638ee1f
Autor:
Joshua E. Drumm, Kaixia Mi, Patrick Bilder, Meihao Sun, Jihyeon Lim, Helle Bielefeldt-Ohmann, Randall Basaraba, Melvin So, Guofeng Zhu, JoAnn M. Tufariello, Angelo A. Izzo, Ian M. Orme, Steve C. Almo, Thomas S. Leyh, John Chan
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9 (2009)
Externí odkaz:
https://doaj.org/article/c0fc356f1d6e4b838d49ad94795b1744
Autor:
Lin, Wang, Emmanuel, Asare, Amol C, Shetty, Freddy, Sanchez-Tumbaco, Megan R, Edwards, Rajagopalan, Saranathan, Brian, Weinrick, Jiayong, Xu, Bing, Chen, Angèle, Bénard, Gordon, Dougan, Daisy W, Leung, Gaya K, Amarasinghe, John, Chan, Christopher F, Basler, William R, Jacobs, JoAnn M, Tufariello
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
Autor:
Stewart W. Schneller, Lin Wang, Caroline G. Williams, Chong Liu, JoAnn M. Tufariello, Christopher F. Basler, Sudip Khadka, Joyce Sweeney Gibbons
Publikováno v:
Antiviral Res
3-deazaneplanocin A (DzNep) and its 3-brominated analogues inhibit replication of several RNA viruses. This antiviral activity is attributed to inhibition of S-adenosyl homocysteine hydrolase (SAHase) and consequently inhibition of viral methyltransf
Autor:
Guofeng Zhu, Jordi B. Torrelles, Catherine Vilchèze, Sivagami Sundaram Chavadi, Simren Mehta, Lijun Bi, Ganduri Swapna, William R. Jacobs, Steven A. Porcelli, Kaixia Mi, TuKiet T. Lam, Syun-Ru Yeh, JoAnn M. Tufariello, Chenyang Zhan, John Chan, Jesus Arcos, Steve C. Almo, Lisa N. Glass, Joshua E. Drumm, Yong Chen
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)
PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)
We have previously shown that the Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth and may be required for the establishment of tuberculous persistence. Here, yeast two-hybrid and affinity chromatography exper
Autor:
Joel D. Ernst, Patricia S. Grace, Thais Klevorn, Aleena Zahra, Alka Mehra, William R. Jacobs, Heidi S. Park, Cynthia Portal-Celhay, Jennifer A. Philips, Smita Srivastava, JoAnn M. Tufariello
Publikováno v:
Nature microbiology, vol 2, iss 2
Mycobacterium tuberculosis (Mtb) establishes a persistent infection, despite inducing antigen-specific T-cell responses. Although T cells arrive at the site of infection, they do not provide sterilizing immunity. The molecular basis of how Mtb impair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2ba0de5de9045d064426f74afbc887
https://europepmc.org/articles/PMC5453184/
https://europepmc.org/articles/PMC5453184/