Differential Regulation of Intracisternally Injected Angiotensin II-Induced Mechanical Allodynia and Thermal Hyperalgesia in Rats

Autor: Ki-Don Park, Jo-Young Son, Hak-Kyun Kim, Yu-Mi Kim, Jin-Sook Ju, Min-Jeong Jo, Min-Kyoung Park, Min-Kyung Lee, Dong-Kuk Ahn

Publikováno v: Biomedicines, Vol 11, Iss 12, p 3279 (2023)

The present study examined the underlying mechanisms of mechanical allodynia and thermal hyperalgesia induced by the intracisternal injection of angiotensin (Ang) II. Intracisternal Ang II injection decreased the air puff threshold and head withdrawa

Externí odkaz: https://doaj.org/article/b9c0b3802f06432d8b1633f73642bd45

TNF-α-Mediated RIPK1 Pathway Participates in the Development of Trigeminal Neuropathic Pain in Rats

Autor: Jo Young Son, Jin Sook Ju, Yu Mi Kim, Dong Kuk Ahn

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 1, p 506 (2022)

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) participates in the regulation of cellular stress and inflammatory responses, but its function in neuropathic pain remains poorly understood. This study evaluated the role of RIPK1 in neu

Externí odkaz: https://doaj.org/article/adb5b14bb17c4f69a40836a1e162b019

Early Blockade of EphA4 Pathway Reduces Trigeminal Neuropathic Pain

Autor: Min-Ji Kim, Jin-Sook Ju, Dong-Kuk Ahn, Jo-Young Son

Publikováno v: Journal of Pain Research. 13:1173-1183

Background Although the Eph receptor plays an important role in the development of neuropathic pain following nerve injury, there has been no evidence of the participation of the ephrin A4 receptor (EphA4) in the development of trigeminal neuropathic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1009b92e4bf36512afbb2f1fee18fdd9
https://doi.org/10.2147/jpr.s249185

Mannitol Enhances the Antinociceptive Effects of Diphenhydramine as an Alternative Local Anesthetic

Autor: Jae-Hyeong Park, Jae-Hyung Park, Jun-Suk Oh, Myeong-Shin Kim, Jae-Seong Lim, Hyun-Wu Yoon, Jung-Ho Park, Jo-Young Son, Jin-Sook Ju, Dong-Kuk Ahn

Publikováno v: Pain Research and Management, Vol 2020 (2020)
Pain Research & Management

Mannitol has recently been reported to be effective in enhancing the antinociceptive efficacy of lidocaine. No single study to date, however, has compared diphenhydramine with and without mannitol for nociceptive processing as an alternative local an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5de41bce40815561061ae0985b6c126

Preemptive application of QX-314 attenuates trigeminal neuropathic mechanical allodynia in rats

Autor: Jin-Sook Ju, Song-Hee Kang, Jeong-Ho Yoon, Jo-Young Son, Min-Ji Kim, Dong-Kuk Ahn, Yong Chul Bae

Publikováno v: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology

The aim of the present study was to examine the effects of preemptive analgesia on the development of trigeminal neuropathic pain. For this purpose, mechanical allodynia was evaluated in male Sprague-Dawley rats using chronic constriction injury of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19307c4645ada6ef4e607f1f07512a56
https://pubmed.ncbi.nlm.nih.gov/29719455