Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Jo Van Damme"'
Autor:
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical application
Externí odkaz:
https://doaj.org/article/a3beb009fdca434c94d95233677ef312
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Originally, it was thought that a single serum amyloid A (SAA) protein was involved in amyloid A amyloidosis, but in fact, SAA represents a four‐membered family wherein SAA1 and SAA2 are acute phase proteins (A-SAA). SAA is highly conserved through
Externí odkaz:
https://doaj.org/article/f89a0274955148a2a1992a8dbe679d81
Autor:
Fariba Poosti, Mohammad Ayodhia Soebadi, Helena Crijns, Alexandra De Zutter, Mieke Metzemaekers, Nele Berghmans, Vincent Vanheule, Maarten Albersen, Ghislain Opdenakker, Jo Van Damme, Ben Sprangers, Paul Proost, Sofie Struyf
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 2, Pp n/a-n/a (2022)
Abstract Objectives Renal fibrosis accompanies all chronic kidney disorders, ultimately leading to end‐stage kidney disease and the need for dialysis or even renal replacement. As such, renal fibrosis poses a major threat to global health and the s
Externí odkaz:
https://doaj.org/article/bd9c21f8f6074be9b98c363f5b2c851e
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Uveitis associated with Vogt-Koyanagi-Harada (VKH) disease is a bilateral, chronic, granulomatous autoimmune disease associated with vitiligo, poliosis, alopecia, and meningeal and auditory manifestations. The disease affects pigmented races with a p
Externí odkaz:
https://doaj.org/article/e1f4a77998014789aa6f069e7d0c95bd
Autor:
Bernard Grillet, Karen Yu, Estefania Ugarte-Berzal, Rik Janssens, Rafaela Vaz Sousa Pereira, Lise Boon, Erik Martens, Nele Berghmans, Isabelle Ronsse, Ilse Van Aelst, Pierre Fiten, René Conings, Jennifer Vandooren, Patrick Verschueren, Jo Van Damme, Paul Proost, Ghislain Opdenakker
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectivesTo explore posttranslational modifications (PTMs), including proteolytic activation, multimerization, complex formation and citrullination of gelatinases, in particular of gelatinase B/MMP-9, and to detect in gelatin-Sepharose affinity-puri
Externí odkaz:
https://doaj.org/article/fcdb7e2221a94516bc4d928080b5e8a7
Autor:
Mieke Metzemaekers, Sara Abouelasrar Salama, Jennifer Vandooren, Anneleen Mortier, Rik Janssens, Sofie Vandendriessche, Eva Ganseman, Erik Martens, Mieke Gouwy, Barbara Neerinckx, Patrick Verschueren, Lien De Somer, Carine Wouters, Sofie Struyf, Ghislain Opdenakker, Jo Van Damme, Paul Proost
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
With ELISAs one detects the ensemble of immunoreactive molecules in biological samples. For biomolecules undergoing proteolysis for activation, potentiation or inhibition, other techniques are necessary to study biology. Here we develop methodology t
Externí odkaz:
https://doaj.org/article/98eedf5312eb4a159a82972e990bd062
Autor:
Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Ajmal Ahmad, Alexandra De Zutter, Mohammad Mairaj Siddiquei, Marfa Blanter, Eef Allegaert, Priscilla W. Gikandi, Gert De Hertogh, Jo Van Damme, Ghislain Opdenakker, Sofie Struyf
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The transmembrane chemokine pathways CXCL16/CXCR6 and CX3CL1/CX3CR1 are strongly implicated in inflammation and angiogenesis. We investigated the involvement of these chemokine pathways and their processing metalloproteinases ADAM10 and ADAM17 in the
Externí odkaz:
https://doaj.org/article/96070714f230472782f75f5efe1485f3
Autor:
Sara Abouelasrar Salama, Mirre De Bondt, Mieke De Buck, Nele Berghmans, Paul Proost, Vivian Louise Soares Oliveira, Flavio A. Amaral, Mieke Gouwy, Jo Van Damme, Sofie Struyf
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Infection, sterile injury, and chronic inflammation trigger the acute phase response in order to re-establish homeostasis. This response includes production of positive acute phase proteins in the liver, such as members of the serum amyloid A (SAA) f
Externí odkaz:
https://doaj.org/article/8f543bb649f0453ea4a489ed95253619
Autor:
Sara Abouelasrar Salama, Mirre De Bondt, Nele Berghmans, Mieke Gouwy, Vivian Louise Soares de Oliveira, Sergio C. Oliveira, Flavio A. Amaral, Paul Proost, Jo Van Damme, Sofie Struyf, Mieke De Buck
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
The serum amyloid A (SAA) gene family is highly conserved and encodes acute phase proteins that are upregulated in response to inflammatory triggers. Over the years, a considerable amount of literature has been published attributing a wide range of b
Externí odkaz:
https://doaj.org/article/9d98eb1390c849428a2061beef83c39f
Autor:
Ahmed M. Abu El-Asrar, Ajmal Ahmad, Mohammad Mairaj Siddiquei, Alexandra De Zutter, Eef Allegaert, Priscilla W. Gikandi, Gert De Hertogh, Jo Van Damme, Ghislain Opdenakker, Sofie Struyf
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The macrophage migration inhibitory factor (MIF)/CD74 signaling pathway is strongly implicated in inflammation and angiogenesis. We investigated the expression of MIF and its receptor CD74 in proliferative diabetic retinopathy (PDR) to reveal a possi
Externí odkaz:
https://doaj.org/article/52cc607bd4ea4f178bace0522c934d05