Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Jo Spencer"'
Autor:
Lucia Montorsi, Michael J. Pitcher, Yuan Zhao, Chiara Dionisi, Alicia Demonti, Thomas J. Tull, Pawan Dhami, Richard J. Ellis, Cynthia Bishop, Jeremy D. Sanderson, Sahil Jain, David D’Cruz, Deena L. Gibbons, Thomas H. Winkler, Mats Bemark, Francesca D. Ciccarelli, Jo Spencer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Intestinal homeostasis is maintained by the response of gut-associated lymphoid tissue to bacteria transported across the follicle associated epithelium into the subepithelial dome. The initial response to antigens and how bacteria are handl
Externí odkaz:
https://doaj.org/article/335f7b7096184522be8b2a65d72908f9
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 9, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/647d5b5358524503adde473bac98d51b
Autor:
Michele Bortolomeazzi, Lucia Montorsi, Damjan Temelkovski, Mohamed Reda Keddar, Amelia Acha-Sagredo, Michael J. Pitcher, Gianluca Basso, Luigi Laghi, Manuel Rodriguez-Justo, Jo Spencer, Francesca D. Ciccarelli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Current high-dimension imaging data analysis methods are technology-specific and require multiple tools, restricting analytical scalability and result reproducibility. Here the authors present SIMPLI, a software that overcomes these limitations for s
Externí odkaz:
https://doaj.org/article/1fa5562be7814b96821061d920d46143
Autor:
Jeffrey Seow, Carl Graham, Sadie R. Hallett, Thomas Lechmere, Thomas J.A. Maguire, Isabella Huettner, Daniel Cox, Hataf Khan, Suzanne Pickering, Rebekah Roberts, Anele Waters, Christopher C. Ward, Christine Mant, Michael J. Pitcher, Jo Spencer, Julie Fox, Michael H. Malim, Katie J. Doores
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110757- (2022)
Summary: Although the antibody response to COVID-19 vaccination has been studied extensively at the polyclonal level using immune sera, little has been reported on the antibody response at the monoclonal level. Here, we isolate a panel of 44 anti-SAR
Externí odkaz:
https://doaj.org/article/c8a108ba74b346e4ac6cb60515b0c6d2
Autor:
Silvia C. Trevelin, Suzanne Pickering, Katrina Todd, Cynthia Bishop, Michael Pitcher, Jose Garrido Mesa, Lucia Montorsi, Filomena Spada, Nedyalko Petrov, Anna Green, Manu Shankar-Hari, Stuart J.D. Neil, Jo Spencer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Confirmed SARS-coronavirus-2 infection with gastrointestinal symptoms and changes in microbiota associated with coronavirus disease 2019 (COVID-19) severity have been previously reported, but the disease impact on the architecture and cellularity of
Externí odkaz:
https://doaj.org/article/14c0a19d8fde40d3a75d23e149ec16ed
Autor:
Gaurav Chatterjee, Trupti Pai, Thomas Hardiman, Kelly Avery-Kiejda, Rodney J. Scott, Jo Spencer, Sarah E. Pinder, Anita Grigoriadis
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-12 (2018)
Abstract Lymph node (LN) metastasis is an important prognostic parameter in breast carcinoma, a crucial site for tumour–immune cell interaction and a gateway for further dissemination of tumour cells to other metastatic sites. To gain insight into
Externí odkaz:
https://doaj.org/article/d2805c0f40a84bb6bf6d73d428f0c398
Autor:
Yuan Zhao, Mohamed Uduman, Jacqueline H. Y. Siu, Thomas J. Tull, Jeremy D. Sanderson, Yu-Chang Bryan Wu, Julian Q. Zhou, Nedyalko Petrov, Richard Ellis, Katrina Todd, Konstantia-Maria Chavele, William Guesdon, Anna Vossenkamper, Wayel Jassem, David P. D’Cruz, David J. Fear, Susan John, Dagmar Scheel-Toellner, Claire Hopkins, Estefania Moreno, Natalie L. Woodman, Francesca Ciccarelli, Susanne Heck, Steven H. Kleinstein, Mats Bemark, Jo Spencer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Human memory and marginal zone B cells share some features including CD27 expression and somatic hypermutation, but their lineage relationship is still unclear. Here the authors use mass cytometry and sequential clustering methods to show that, despi
Externí odkaz:
https://doaj.org/article/18e17622ab574decbfaad7cce6011bef
Autor:
Rebeca Jimeno, Marta Lebrusant-Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gurdyal S Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/5f1a7d5da2884a64994b7fb75f7522c0
Autor:
Rebeca Jimeno, Marta Lebrusant-Fernandez, Christian Margreitter, Beth Lucas, Natacha Veerapen, Gavin Kelly, Gurdyal S Besra, Franca Fraternali, Jo Spencer, Graham Anderson, Patricia Barral
Publikováno v:
eLife, Vol 8 (2019)
Tissue homeostasis is critically dependent on the function of tissue-resident lymphocytes, including lipid-reactive invariant natural killer T (iNKT) cells. Yet, if and how the tissue environment shapes the antigen specificity of iNKT cells remains u
Externí odkaz:
https://doaj.org/article/34fc56718d5d43af9798a8ee9d6a3781
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-7 (2018)
Abstract Background Sepsis remains a major cause of mortality in critical care, for which specific treatments are lacking. The dysregulated response to infection seen in sepsis includes features of lymphocyte dysfunction and exhaustion, suggesting th
Externí odkaz:
https://doaj.org/article/73391f1c17804f3eaa4e1a95c67a8854