Výsledky vyhledávání - "Jo Slater-Jefferies"

Akademický článek

Global challenges and microbial biofilms: Identification of priority questions in biofilm research, innovation and policy

Publikováno v: Biofilm, Vol 8, Iss , Pp 100210- (2024)

Priority question exercises are increasingly used to frame and set future research, innovation and development agendas. They can provide an important bridge between the discoveries, data and outputs generated by researchers, and the information requi

Externí odkaz: https://doaj.org/article/0b18089ed6a242b99e90f01db0a799d2

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Akademický článek

Creating pathways for collaboration between Argentina and the UK to utilise microbial biofilms in sustainable agriculture

Autor: Patricia L. Abdian, Miguel Cámara, Fabricio D. Cassan, Gabriel Castrillo, Marisa Díaz, Gustavo Gonzalez Anta, Claire Hodge, Jo Slater-Jefferies, Cait E. MacPhee, Enzo Moriconi, Paulina D. Rakowska, Rasmita Raval, Duncan Ross, Juan F. Sandoval, Diego O. Serra, Claudio Valverde, Jeremy Webb, Ana Winters

Publikováno v: CABI Agriculture and Bioscience, Vol 5, Iss 1, Pp 1-8 (2024)

Abstract Microbial biofilms are complex communities of microorganisms that exist in various environments, including natural and human-built systems and have a significant economic impact on a global scale. In addition to their detrimental impacts, bi

Externí odkaz: https://doaj.org/article/021a0c22a37e4ff3a71905a981369fbc

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Evaluation of Methylation Status of the eNOS Promoter at Birth in Relation to Childhood Bone Mineral Content

Autor: Joanne Rodford, Emma Garratt, Allan Sheppard, Bright Starling Emerald, Nicholas C. Harvey, Graham C. Burdge, Hazel Inskip, Cameron McLean, Jo Slater-Jefferies, Peter D. Gluckman, Catharine R. Gale, Cyrus Cooper, Keith M. Godfrey, Mark A. Hanson, Sarah Crozier, Karen A. Lillycrop

Publikováno v: Calcified Tissue International. 90:120-127

Our previous work has shown associations between childhood adiposity and perinatal methylation status of several genes in umbilical cord tissue, including endothelial nitric oxide synthase (eNOS). There is increasing evidence that eNOS is important i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d311a31d794551246289ecdc56da65
https://doi.org/10.1007/s00223-011-9554-5

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Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications

Autor: Alan Jackson, Mark A. Hanson, Graham C. Burdge, Jo Slater-Jefferies, Karen A. Lillycrop, Keith M. Godfrey

Publikováno v: British Journal of Nutrition. 97:1064-1073

Prenatal nutritional constraint induces an altered metabolic phenotype in the offspring which in humans confers an increased risk of non-communicable disease. Feeding a protein-restricted (PR) diet to pregnant rats causes hypomethylation of specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbecb1c978c9aac3614431595ea3798
https://doi.org/10.1017/s000711450769196x

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Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations

Autor: Graham C. Burdge, Christopher Torrens, Mark A. Hanson, Karen A. Lillycrop, Jo Slater-Jefferies, E.S. Phillips

Publikováno v: British Journal of Nutrition. 97:435-439

Epidemiological studies and experimental models show that maternal nutritional constraint during pregnancy alters the metabolic phenotype of the offspring and that this can be passed to subsequent generations. In the rat, induction of an altered meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4802a74b63cba119cbbb1de11d071214
https://doi.org/10.1017/s0007114507352392

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Feeding a protein-restricted diet during pregnancy induces altered epigenetic regulation of peroxisomal proliferator-activated receptor-α in the heart of the offspring

Autor: Samuel P. Hoile, Mark A. Hanson, Paul A. Townsend, Christopher Torrens, Karen A. Lillycrop, Jo Slater-Jefferies, Graham C. Burdge

Impaired flexibility in the use of substrates for energy production in the heart is implicated in cardiomyopathy. We investigated the effect of maternal protein restriction during pregnancy in rats on the transcription of key genes in cardiac lipid a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04363a5fe496379dd48eb441890012
https://europepmc.org/articles/PMC3191520/

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Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life?

Autor: Graham C. Burdge, Mark A. Hanson, Karen A. Lillycrop, Jo Slater-Jefferies

Publikováno v: The British journal of nutrition. 97(6)

There is considerable evidence for the induction of different phenotypes by variations in the early life environment, including nutrition, which in man is associated with a graded risk of metabolic disease; fetal programming. It is likely that the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a78ead33e8e9fd4a51de79641529bef
https://pubmed.ncbi.nlm.nih.gov/17381976

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