Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jo S. Zulkoski"'
Publikováno v:
Biochemical Pharmacology. 31:639-646
Studies were carried out to compare the metabolism of benzo[ a ]pyrene (BP) by adrenal and hepatic microsomes obtained from adult male guinea pigs. Adrenal microsomes produced fluorescent metabolites (primarily phenols) approximately three to four ti
Publikováno v:
Journal of Toxicology and Environmental Health. 8:907-915
The in vitro effects of Cd, Zn, and Pb on pulmonary, adrenal, and hepatic microsomal enzyme activities in guinea pigs were compared. Cd and Zn produced concentration-dependent (20-200 microM) decreases in benzphetamine demethylase and biphenyl hydrox
Publikováno v:
Toxicology and applied pharmacology. 73(1)
Preincubation of hepatic, adrenal, or pulmonary microsomal preparations with cadmium produced time-dependent decreases in monooxygenase (benzphetamine demethylase, benzo(a)pyrene hydroxylase) activities. Addition of cadmium after the preincubation pe