Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Jo Rae Wright"'
Autor:
Julie G Ledford, Sambuddho Mukherjee, Michele M Kislan, Julia L Nugent, John W Hollingsworth, Jo Rae Wright
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32436 (2012)
Surfactant protein-A (SP-A) has well-established functions in reducing bacterial and viral infections but its role in chronic lung diseases such as asthma is unclear. Mycoplasma pneumoniae (Mp) frequently colonizes the airways of chronic asthmatics a
Externí odkaz:
https://doaj.org/article/923652aded8a42759faadb4f63839d6c
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1370 (2007)
Initiation of a protective immune response to infection by the pathogenic fungus Cryptococcus neoformans is mediated in part by host factors that promote interactions between immune cells and C. neoformans yeast. Surfactant protein A (SP-A) contribut
Externí odkaz:
https://doaj.org/article/991f0082863146d39314eb9aff173348
Autor:
Theresa M. McDevitt, Hongmei Jiang, Aisha Zaman, Jo Rae Wright, Naeun Cheong, Joseph P. Foley, David Lam, Jie Liao, Rashmin C. Savani
Publikováno v:
Journal of Biological Chemistry. 287:37406-37419
The innate immune system protects the host from bacterial and viral invasion. Surfactant protein A (SPA), a lung-specific collectin, stimulates macrophage chemotaxis. However, the mechanisms regulating this function are unknown. Hyaluronan (HA) and i
Autor:
Kymberly M, Gowdy, Diana M, Cardona, Julia L, Nugent, Charles, Giamberardino, Joseph M, Thomas, Sambuddho, Mukherjee, Sambudho, Mukherjee, Tereza, Martinu, W Michael, Foster, Scott E, Plevy, Amy M, Pastva, Jo Rae, Wright, Scott M, Palmer
Publikováno v:
The Journal of Immunology. 188:4897-4905
Graft-versus-host disease (GVHD) is a severe and frequent complication of allogeneic bone marrow transplantation (BMT) that involves the gastrointestinal (GI) tract and lungs. The pathobiology of GVHD is complex and involves immune cell recognition o
Autor:
Kymberly M. Gowdy, Jo Rae Wright, Amy M. Pastva, Joseph M. Thomas, Charles Giamberardino, Sambuddho Mukherjee
Publikováno v:
The Journal of Immunology. 188:4376-4384
TCR signaling plays a critical role in regulatory T cell (Treg) development. However, the mechanism for tissue-specific induction of Tregs in the periphery remains unclear. We observed that surfactant protein A (SP-A)–deficient mice have impaired e
Autor:
Amy M. Pastva, Jo Rae Wright, Joseph M. Thomas, Charles Giamberardino, Bethany J. Hsia, Hisatsugu Goto, Kathy Evans, Julie G. Ledford, Sambuddho Mukherjee
Publikováno v:
The Journal of Immunology. 188:957-967
Pulmonary surfactant lipoproteins lower the surface tension at the alveolar–airway interface of the lung and participate in host defense. Previous studies reported that surfactant protein A (SP-A) inhibits lymphocyte proliferation. We hypothesized
Autor:
Joanna Floros, Njira L Lugogo, Monica Kraft, Daniel H. Fertel, Tony D. Church, Jennifer L. Ingram, Guirong Wang, Pitchaimani Kandasamy, Ying Wang, Hong Wei Chu, Dennis R. Voelker, Jo Rae Wright
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 301:L598-L606
Surfactant protein A (SP-A) regulates a variety of immune cell functions. We determined the ability of SP-A derived from normal and asthmatic subjects to modulate the inflammatory response elicited by Mycoplasma pneumoniae , a pathogen known to exace
Autor:
Charles Giamberardino, Sambuddho Mukherjee, Simone Degan, Timothy J. McMahon, Lee A. Maddox, David A. Schwartz, Julia K. L. Walker, Barbara L. Lawson, Hongmei Zhu, Jerry P. Eu, Thomas R. Korfhagen, Mary E. Sunday, William M. Foster, Jo Rae Wright, Loretta G. Que, Amy M. Pastva, Erin N. Potts, Bethany J. Hsia
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:175-184
THIS ARTICLE WAS RETRACTED ON NOVEMBER 1, 2016. Please see www.atsjournals.org/doi/full/10.1165/rcmb.555retractionSurfactant protein A (SP-A) mediates innate immune cell responses to LPS, a cell wall component of gram-negative bacteria that is found
Publikováno v:
Innate Immunity. 16:183-190
Although the lipoprotein complex of pulmonary surfactant has long been recognized as essential for reducing lung surface tension, its role in lung immune host defense has only relatively recently been elucidated. Surfactant-associated proteins A (SP-
Autor:
Jo Rae Wright, Jessica A. Wofford
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 293:L1437-L1443
Surfactant proteins (SP)-A and SP-D have been shown to affect the functions of a variety of innate immune cells and to interact with various immune proteins such as complement and immunoglobulins. The goal of the current study is to test the hypothes