Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jo Poulton"'
Autor:
Iain G Johnston, Joerg P Burgstaller, Vitezslav Havlicek, Thomas Kolbe, Thomas Rülicke, Gottfried Brem, Jo Poulton, Nick S Jones
Publikováno v:
eLife, Vol 4 (2015)
Dangerous damage to mitochondrial DNA (mtDNA) can be ameliorated during mammalian development through a highly debated mechanism called the mtDNA bottleneck. Uncertainty surrounding this process limits our ability to address inherited mtDNA diseases.
Externí odkaz:
https://doaj.org/article/8019d712523d4708afa02fd46cc2e356
Autor:
Thomas Kolbe, Gottfried Brem, Jo Poulton, Iain G. Johnston, Thomas Rülicke, Joerg P. Burgstaller, Vitezslav Havlicek, Nick S. Jones
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
Dangerous damage to mitochondrial DNA (mtDNA) can be ameliorated during mammalian development through a highly debated mechanism called the mtDNA bottleneck. Uncertainty surrounding this process limits our ability to address inherited mtDNA diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43461a05d4a3e907b0b901f8f828705e
https://pubmed.ncbi.nlm.nih.gov/26035426
https://pubmed.ncbi.nlm.nih.gov/26035426
Autor:
Jo Poulton
Publikováno v:
European Journal of Paediatric Neurology. 2:99-103
It is important to recognize that mitochondrial diseases are systemic conditions and not confined to the nervous system. Many of them manifest neurological disease, however, and the main major features will be listed here. Although many patients fit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9e7184de09a0e3ebc5b0b83986a3ab
https://doi.org/10.1016/s1090-3798(98)80049-4
https://doi.org/10.1016/s1090-3798(98)80049-4
Autor:
Sylvia Bartlett, J F O'Rourke, Jonathan M. Gleadle, Peter J. Ratcliffe, Jo Poulton, Benjamin L. Ebert
Publikováno v:
Scopus-Elsevier
Recent studies have indicated that regulatory mechanisms underlying the oxygen-dependent expression of the haematopoietic growth factor erythropoietin are widely operative in non-erythropoietin-producing cells and are involved in the regulation of ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a245bbe164842c51e8f3c0e6a5bd7d
https://doi.org/10.1042/bj3130809
https://doi.org/10.1042/bj3130809
Publikováno v:
Human Molecular Genetics. 2:23-30
In three patients with mitochondrial DNA duplications, there are two additional re-arranged molecules derived from mitochondrial DNA. Two forms of closed circular deletions of mitochondrial DNA have been characterised in all three patients, one being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113b149443807e88a3a30cb6379dd483
https://doi.org/10.1093/hmg/2.1.23
https://doi.org/10.1093/hmg/2.1.23
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 289(6)
A common mitochondrial (mt)DNA variant that is maternally inherited, the 16189 variant, is associated with type 2 diabetes and thinness at birth. To elucidate the association of the variant with thinness, we studied the 16189 variant in a well-charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172c8cc61a6b11ce699b201bd48fb215
https://pubmed.ncbi.nlm.nih.gov/15998658
https://pubmed.ncbi.nlm.nih.gov/15998658
Autor:
Jo Poulton
Publikováno v:
Neuromuscular Disorders. 18:908-909
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::988e263af2358eacf10c3d23b2140fa5
https://doi.org/10.1016/j.nmd.2007.06.007
https://doi.org/10.1016/j.nmd.2007.06.007
Publikováno v:
The Lancet. 354:2081-2082
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5f7fca684b4a83ed946ddf3e6197002
https://doi.org/10.1016/s0140-6736(05)76823-9
https://doi.org/10.1016/s0140-6736(05)76823-9
Autor:
Kristina Casteels, David I.W. Phillips, Ken Ong, Marcus Pembrey, Jo Poulton, Holly Bendall, David B. Dunger
Publikováno v:
The Lancet. 353:1499-1500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34f076207952fb5d1a51972479e61890
https://doi.org/10.1016/s0140-6736(98)05817-6
https://doi.org/10.1016/s0140-6736(98)05817-6