Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jo Mailleux"'
Autor:
Gemma Llufriu-Dabén, Alex Carrete, Elena Chierto, Jo Mailleux, Emeline Camand, Anne Simon, Tim Vanmierlo, Christiane Rose, Bernadette Allinquant, Jerome J.A. Hendriks, Charbel Massaad, Delphine Meffre, Mehrnaz Jafarian-Tehrani
Publikováno v:
Neurobiology of Disease, Vol 109, Iss , Pp 11-24 (2018)
Remyelination is an endogenous regenerative process of myelin repair in the central nervous system (CNS) with limited efficacy in demyelinating disorders. As strategies enhancing endogenous remyelination become a therapeutic challenge, we have focuse
Externí odkaz:
https://doaj.org/article/c262bbe9326f41d4820553374b0a7fec
Autor:
Jo Mailleux, Silke Timmermans, Katherine Nelissen, Jasmine Vanmol, Tim Vanmierlo, Jack van Horssen, Jeroen F. J. Bogie, Jerome J. A. Hendriks
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
ObjectiveWe aimed to determine the role of the low-density lipoprotein receptor (LDLr) in neuroinflammation by inducing experimental autoimmune encephalomyelitis (EAE) in ldlr knock out mice.MethodsMOG35–55 induced EAE in male and female ldlr−/
Externí odkaz:
https://doaj.org/article/656e348ab9024115bd1bac24d39df599
Autor:
Piet Stinissen, Noam Zelcer, Erwin Wijnands, Silke Timmermans, Knut R. Steffensen, Katherine Nelissen, Jo Mailleux, Monique T. Mulder, Jasmine Vanmol, Kristiaan Wouters, Jan-Åke Gustafsson, Jeroen F. J. Bogie, Tim Vanmierlo, Jerome J. A. Hendriks
Publikováno v:
Journal of autoimmunity, 124:102723. Academic Press Inc.
Journal of Autoimmunity, 124:102723. Academic Press
Journal of Autoimmunity, 124:102723. Elsevier Science
Journal of Autoimmunity, 124:102723. Academic Press
Journal of Autoimmunity, 124:102723. Elsevier Science
The initiation and progression of autoimmune disorders such as multiple sclerosis (MS) is linked to aberrant cholesterol metabolism and overt inflammation. Liver X receptors (LXR) are nuclear receptors that function at the crossroads of cholesterol m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dd23def63f6dfbba5a9991a3724914
https://doi.org/10.1016/j.jaut.2021.102723
https://doi.org/10.1016/j.jaut.2021.102723
Autor:
Jan-Åke Gustafsson, Ivo Lambrichts, Elien Wouters, Jeroen F. J. Bogie, Aida Garcia Corrales, Pascal Gervois, Noam Zelcer, Esther Wolfs, Jo Mailleux, Alan T. Remaley, Tess Dierckx, Jana Van Broeckhoven, Shane R. Ellis, Jerome J. A. Hendriks, Johannes V. Swinnen, Monique T. Mulder, Jonas Dehairs, James M. Ntambi, Sam Vanherle, Andrew P. Bowman, Elien Grajchen, Mansour Haidar
Publikováno v:
Journal of experimental medicine, 217(5):e20191660. Rockefeller University Press
Journal of Experimental Medicine, 217(5):e20191660. Rockefeller University Press
Journal of Experimental Medicine, 217(5):20191660. Rockefeller University Press
The Journal of Experimental Medicine
Journal of Experimental Medicine, 217(5):e20191660. Rockefeller University Press
Journal of Experimental Medicine, 217(5):20191660. Rockefeller University Press
The Journal of Experimental Medicine
In this study, Bogie, Grajchen et al. show that monounsaturated fatty acids formed by stearoyl-CoA desaturase-1 impair the reparative features of macrophages and microglia in demyelinating disorders by reducing their lipid efflux capacity.
Failu
Failu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb29926cf6e54c656c82a5e8513d54a
https://pure.eur.nl/en/publications/776188a2-3dce-4bc3-bbd7-1fa4a9005b85
https://pure.eur.nl/en/publications/776188a2-3dce-4bc3-bbd7-1fa4a9005b85
Autor:
Mehrnaz Jafarian-Tehrani, Anne Simon, Gemma Llufriu-Dabén, Christiane Rose, Jo Mailleux, Delphine Meffre, Emeline Camand, Bernadette Allinquant, Alex Carrete, Elena Chierto, Jerome J. A. Hendriks, Charbel Massaad, Tim Vanmierlo
Publikováno v:
Neurobiology of Disease, Vol 109, Iss, Pp 11-24 (2018)
Remyelination is an endogenous regenerative process of myelin repair in the central nervous system (CNS) with limited efficacy in demyelinating disorders. As strategies enhancing endogenous remyelination become a therapeutic challenge, we have focuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270bd4fc57e885fa338b00cd1522477b
https://doi.org/10.1016/j.nbd.2017.09.008
https://doi.org/10.1016/j.nbd.2017.09.008
Autor:
Elien Wouters, Dieter Lütjohann, Jerome J. A. Hendriks, Jeroen F. J. Bogie, Tim Vanmierlo, Jo Mailleux, Jack van Horssen
Publikováno v:
Multiple Sclerosis, 24(3), 279-289. SAGE Publications Ltd
Mailleux, J, Vanmierlo, T, Bogie, J F, Wouters, E, Lütjohann, D, Hendriks, J J & van Horssen, J 2018, ' Active liver X receptor signaling in phagocytes in multiple sclerosis lesions ', Multiple Sclerosis, vol. 24, no. 3, pp. 279-289 . https://doi.org/10.1177/1352458517696595
Mailleux, J, Vanmierlo, T, Bogie, J F, Wouters, E, Lütjohann, D, Hendriks, J J & van Horssen, J 2018, ' Active liver X receptor signaling in phagocytes in multiple sclerosis lesions ', Multiple Sclerosis, vol. 24, no. 3, pp. 279-289 . https://doi.org/10.1177/1352458517696595
Objective:We sought to determine the liver X receptor (LXR) ligands present in human macrophages after myelin phagocytosis and whether LXRs are activated in multiple sclerosis (MS) lesions.Methods:We used real-time quantitative polymerase chain react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3544204d18edeb350d531f5059a31b
https://doi.org/10.1177/1352458517696595
https://doi.org/10.1177/1352458517696595
Autor:
Jerome J. A. Hendriks, Elien Wouters, Winde Jorissen, Jeroen F. J. Bogie, Elien Grajchen, Jasmine Vanmol, Niels Hellings, Tim Vanmierlo, Jack van Horssen, Kristiaan Wouters, Jo Mailleux
Publikováno v:
Scientific Reports
Myelin-containing macrophages and microglia are the most abundant immune cells in active multiple sclerosis (MS) lesions. Our recent transcriptomic analysis demonstrated that collectin placenta 1 (CL-P1) is one of the most potently induced genes in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296e80a9ae9d871dd5e61457f7de1486
https://doi.org/10.1038/srep46925
https://doi.org/10.1038/srep46925
Autor:
Jasmine Vanmol, Silke Timmermans, Jo Mailleux, Jerome J. A. Hendriks, Jeroen F. J. Bogie, Tim Vanmierlo, Katherine Nelissen, Jack van Horssen
Publikováno v:
Frontiers in Immunology, 8(NOV):1701. Frontiers Media S.A.
Mailleux, J, Timmermans, S, Nelissen, K, Vanmol, J, Vanmierlo, T, van Horssen, J, Bogie, J F J & Hendriks, J J A 2017, ' Low-density lipoprotein receptor deficiency attenuates neuroinflammation through the induction of apolipoprotein E ', Frontiers in Immunology, vol. 8, no. NOV, 1701 . https://doi.org/10.3389/fimmu.2017.01701
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Mailleux, J, Timmermans, S, Nelissen, K, Vanmol, J, Vanmierlo, T, van Horssen, J, Bogie, J F J & Hendriks, J J A 2017, ' Low-density lipoprotein receptor deficiency attenuates neuroinflammation through the induction of apolipoprotein E ', Frontiers in Immunology, vol. 8, no. NOV, 1701 . https://doi.org/10.3389/fimmu.2017.01701
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Objective: We aimed to determine the role of the low-density lipoprotein receptor (LDLr) in neuroinflammation by inducing experimental autoimmune encephalomyelitis (EAE) in ldlr knock out mice. Methods: MOG35–55 induced EAE in male and female ldlr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7145fa33d57167d8db8798fabf9cab79
https://doi.org/10.3389/fimmu.2017.01701
https://doi.org/10.3389/fimmu.2017.01701
Autor:
Niels Hellings, Jerome J. A. Hendriks, Jasmine Vanmol, Tim Vanmierlo, Elien Grajchen, Jo Mailleux, Jeroen F. J. Bogie, Elien Wouters, Winde Jorissen, Kristiaan Wouters, Jack Van Horsen
Publikováno v:
Scientific Reports, 7:44794. Nature Publishing Group
Bogie, J F J, Mailleux, J, Wouters, E, Jorissen, W, Grajchen, E, Vanmol, J, Wouters, K, Hellings, N, Van Horsen, J, Vanmierlo, T & Hendriks, J J A 2017, ' Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes ', Scientific Reports, vol. 7, 44794 . https://doi.org/10.1038/srep44794
Scientific Reports
Bogie, J F J, Mailleux, J, Wouters, E, Jorissen, W, Grajchen, E, Vanmol, J, Wouters, K, Hellings, N, Van Horsen, J, Vanmierlo, T & Hendriks, J J A 2017, ' Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes ', Scientific Reports, vol. 7, 44794 . https://doi.org/10.1038/srep44794
Scientific Reports
Myelin-containing macrophages and microglia are the most abundant immune cells in active multiple sclerosis (MS) lesions. Our recent transcriptomic analysis demonstrated that collectin placenta 1 (CL-P1) is one of the most potently induced genes in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc86c258d70cef74f91a97996841cdd
https://doi.org/10.1038/srep44794
https://doi.org/10.1038/srep44794
Autor:
Jasmine Vanmol, Jeroen F. J. Bogie, Tim Vanmierlo, Dieter Lütjohann, Jo Mailleux, Jerome J. A. Hendriks, Monique T. Mulder
Publikováno v:
Progress in Lipid Research, 58, 26-39. Elsevier Ltd.
In mammals, the central nervous system (CNS) is the most cholesterol rich organ by weight. Cholesterol metabolism is tightly regulated in the CNS and all cholesterol available is synthesized in situ. Deficits in cholesterol homeostasis at the level o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d991d634277a2c6ba50e264815fda1c0
https://pure.eur.nl/en/publications/3d6ab70b-042a-4a6b-b49e-51abcd0dd1e9
https://pure.eur.nl/en/publications/3d6ab70b-042a-4a6b-b49e-51abcd0dd1e9
