Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jo M. Grimley"'
Publikováno v:
Hepatology. 15:923-927
The organochlorine compound mirex (dodecachlorooctahydro-1,3,4-metheno-2H-cyclobuta-CD-pentalene) induces an adaptive liver growth dependent on the hormonal status of the experimental animal. In the intact laboratory rat, mirex induces liver growth t
Publikováno v:
Biological Mass Spectrometry. 20:443-450
In a hybrid instrument under minimal multiple-collision conditions, the collision-induced fragmentation of the [M + H]+ ions of tetraalanine and tetraglycine are dominated by the gamma 2 fragment, in distinction to the fragmentation of the [M + H]+ i
Autor:
Jo M. Grimley, James D. Yarbrough
Publikováno v:
Pesticide Biochemistry and Physiology. 25:366-372
α-Hexachlorocyclohexane was administered as a single oral dose (100 mg/kg body wt) to both intact and adrenalectomized male Sprague-Dawley rats. In the intact rats there was a peak in [3H]thymidine incorporation into DNA at 30 hr and an increase in
Publikováno v:
Inorganic Chemistry. 15:1716-1718
Publikováno v:
Chemischer Informationsdienst. 7
Publikováno v:
Cell and tissue kinetics. 17(5)
The adaptive liver growth response was investigated in intact and adrenalectomized rats. When adult male rats were given a single oral dose of mirex (100 mg/kg body weight) there was a 72% increase in relative liver weight (RLW) in 72 hr. Based on [3
Autor:
Janice E. Chambers, Earl G. Alley, James D. Conroy, Ming-Ming Fang, Billy C. Ward, Jo M. Grimley, James D. Yarbrough, John T. Morrow
Publikováno v:
Toxicology and applied pharmacology. 58(1)
Male rats were fed 0, 0.5, 5.0, 50, and 75 ppm mirex or 8-monohydromirex for 28 days. There were no consistent differences between weight gain of treated or control groups. There were significant increases in LW/BW in the 5, 50, and 75 ppm mirex and
Publikováno v:
Toxicology letters. 32(1-2)
The hepatic induction of cytochrome P-450-dependent monooxygenase components by cis- and trans-5,10-dihydrogen mirex was studied in male and female laboratory rats. There were sex-dependent differences between the two isomeric derivatives of mirex. T