Sex and intimacy in people with severe asthma: a qualitative study

Autor: Leanne Jo Holmes, Janelle A Yorke, Caroline Dutton, Stephen J Fowler, Dorothy Ryan

Publikováno v: BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)

Introduction People with severe asthma experience unpredictable daily symptoms requiring an intense treatment regimen impacting on health-related quality of life (QoL). Sexuality contributes to this, yet there is a dearth of research exploring intima

Externí odkaz: https://doaj.org/article/b68d5226ed91416d8d58ea1e1a31dadd

Severe asthma outcomes over 18-months treatment with mepolizumab, and comorbidities in non-responders

Autor: James Wingfield-Derby, Leanne Jo Holmes, Thomas Pantin, L Elsey, Lorna Maguire, Kate Newman, Stephen J. Fowler

Publikováno v: Airway pharmacology and treatment.

Introduction: Mepolizumab is an anti-IL-5 monoclonal antibody indicated for the treatment of severe asthma. We have evaluated patient outcomes over the first 18-months of treatment, and investigated comorbidities in non-responders. Method: Data from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a0c46f828a42baa19fe84afa607014e
https://doi.org/10.1183/13993003.congress-2020.2256

Prevalence of adrenal insufficiency in patients started on Mepolizumab for severe eosinophilic asthma

Autor: Nusrat Bholah, D Allen, Leanne Jo Holmes, Robert Niven, L Elsey, G Tavernier

Publikováno v: Airway pharmacology and treatment.

Background: Manchester severe asthma team have treated 243 patients to date with Mepolizumab since it became available in the UK for the treatment of severe eosinophilic asthma in April 2017. Patients are weaned off their maintenance steroids followi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b0ecae81ce11c79e3473d75b940260b
https://doi.org/10.1183/13993003.congress-2019.pa2512

A randomised controlled feasibility trial of Group Cognitive Behavioural Therapy for people with severe asthma

Autor: Anne-Marie Doyle, Andrew Menzies-Gow, Janelle Yorke, Pauline Adair, Leanne Jo Holmes, Linda Dubrow-Marshall, Robert Niven, Caroline Shuldham, Mark Pilling, Sharon Fleming

Publikováno v: Yorke, J, Adair, P, Doyle, A-M, Dubrow-Marshall, L, Fleming, S L, Holmes, L, Menzies-Gow, A, Niven, R, Pilling, M & Shuldham, C 2017, ' A randomised controlled feasibility trial of Group Cognitive Behavioural Therapy for people with severe asthma ', Journal of Asthma, vol. 54, no. 5, pp. 543-554 . https://doi.org/10.1080/02770903.2016.1229335
Yorke, J, Adair, P, Doyle, A-M, Dubrow-Marshall, L, Fleming, S, Holmes, L & Shuldham, C 2016, ' A randomised controlled feasibility trial of Group Cognitive Behavioural Therapy for people with severe asthma ', Journal of Asthma . https://doi.org/10.1080/02770903.2016.1229335

Objectives: Evidence for the efficacy of Cognitive Behavioural Therapy (CBT) in asthma is developing but it is not known if this translates to benefits in severe asthma or if a group approach is acceptable to this patient group. This study aimed to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31722cc3f1874e45aa2009c3e25592e2
https://doi.org/10.1080/02770903.2016.1229335

Cognitive impairment in patients with eosinophilic granulomatosis with polyangiitis (EGPA): Service evaluation in a regional severe asthma centre in North-west England

Autor: Binita Kane, D Ryan, Sarah Diver, Robert Niven, Leanne Jo Holmes, Steve Fowler

Publikováno v: 1.11 Clinical Problems - Asthma.

Background: Cognitive decline in EGPA is rare. 30% of patients with small vessel vasculitis may have subclinical neuropsychological impairment 1 . Data is limited regarding EGPA alone. Aim: To evaluate prevalence of cognitive impairment in patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0bd784e6f513e90a4b413cf2214af01
https://doi.org/10.1183/13993003.congress-2016.pa5017