Zobrazeno 1 - 10 of 130 pro vyhledávání: '"Jo G R, De Mey"'
1
Akademický článek
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Autor: Mahmoud H Elbatreek, Sepideh Sadegh, Elisa Anastasi, Emre Guney, Cristian Nogales, Tim Kacprowski, Ahmed A Hassan, Andreas Teubner, Po-Hsun Huang, Chien-Yi Hsu, Paul M H Schiffers, Ger M Janssen, Pamela W M Kleikers, Anil Wipat, Jan Baumbach, Jo G R De Mey, Harald H H W Schmidt
Publikováno v: PLoS Biology, Vol 18, Iss 11, p e3000885 (2020)
Hypertension is the most important cause of death and disability in the elderly. In 9 out of 10 cases, the molecular cause, however, is unknown. One mechanistic hypothesis involves impaired endothelium-dependent vasodilation through reactive oxygen s
Externí odkaz: https://doaj.org/article/59e3c69f9059443b811c06990062c088
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2
Akademický článek
Local enrichment of fatty acid-binding protein 4 in the pericardial cavity of cardiovascular disease patients.
Autor: Atlanta G I M Elie, Maria Bloksgaard, Wai Y Sun, Kangmin Yang, Andy W C Man, Aimin Xu, Akhmadjon Irmukhamedov, Lars P Riber, Yu Wang, Jo G R De Mey
Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0206802 (2018)
BACKGROUND:The pericardial fluid may be representative of the interstitium of the heart. The aim of this study was to discriminate in cardiovascular disease patients between adipocytokines that are produced locally by the heart and those supplied by
Externí odkaz: https://doaj.org/article/95212b621a70419fb54eacf015221939
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3
Sympathetic and sensory-motor nerves in peripheral small arteries
Autor: Jo G. R. De Mey, Holger Nilsson, Christian Aalkjaer
Publikováno v: Aalkjaer, C, Nilsson, H & De Mey, J G R 2021, ' Sympathetic and sensory-motor nerves in peripheral small arteries ', Physiological Reviews, vol. 101, no. 2, pp. 495-544 . https://doi.org/10.1152/physrev.00007.2020
Small arteries, which play important roles in controlling blood flow, blood pressure, and capillary pressure, are under nervous influence. Their innervation is predominantly sympathetic and sensory motor in nature, and while some arteries are densely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6004f1bb613d1f1a9353f7e4a54633ed
https://doi.org/10.1152/physrev.00007.2020
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4
Retinal Vascular Fractal Dimensions and Their Association with Macrovascular Cardiac Disease
Autor: Jo G. R. De Mey, Maria Bloksgaard, Lars Melholt Rasmussen, Pia Søndergaard Jensen, Sebastian Dinesen, Jakob Grauslund, Søren Leer Blindbæk, Jes S. Lindholt
Publikováno v: Ophthalmic Research, 64(4), 561-566. S. Karger AG
Dinesen, S, Jensen, P S, Bloksgaard, M, Blindbæk, S L, De Mey, J G R, Rasmussen, L M, S Lindholt, J & Grauslund, J 2021, ' Retinal vascular fractal dimensions and their association with macrovascular cardiac disease ', Ophthalmic Research, vol. 64, no. 4, pp. 561-566 . https://doi.org/10.1159/000514442
Introduction: As the only part of the human vasculature, the retina is available for direct, noninvasive inspection. Retinal vascular fractal dimension (DF) is a method to measure the structure of the retinal vascular tree, with higher noninteger val
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502eb45be67bd587f6fdfff599a7da36
https://doi.org/10.1159/000514442
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5
Akademický článek
Adipokine Imbalance in the Pericardial Cavity of Cardiac and Vascular Disease Patients.
Autor: Atlanta G I M Elie, Pia S Jensen, Katrine D Nissen, Ilvy M E Geraets, Aimin Xu, Erfei Song, Maria L Hansen, Akhmadjon Irmukhamedov, Lars M Rasmussen, Yu Wang, Jo G R De Mey
Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0154693 (2016)
AIM:Obesity and especially hypertrophy of epicardial adipose tissue accelerate coronary atherogenesis. We aimed at comparing levels of inflammatory and atherogenic hormones from adipose tissue in the pericardial fluid and circulation of cardiovascula
Externí odkaz: https://doaj.org/article/65a407adbd654c258c1172ec19e44c0f
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6
Coronary artery bypass surgery independently associates with retinal vascular oxygen saturation
Autor: Pia Søndergaard Jensen, Lars M. Rasmusssen, Maria Bloksgaard, Sebastian Dinesen, Jo G. R. De Mey, Jakob Grauslund, Jes S. Lindholt
Publikováno v: Acta Ophthalmologica, 98(7), 709-715. Wiley
Dinesen, S, Jensen, P S, Bloksgaard, M, Mey, J D, S.Lindholt, J, Rasmusssen, L M & Grauslund, J 2020, ' Coronary artery bypass surgery independently associates with retinal vascular oxygen saturation ', Acta Ophthalmologica, vol. 98, no. 7, pp. 709-715 . https://doi.org/10.1111/aos.14444
Purpose: The retinal vasculature is the only part of the microcirculation that can be directly studied by non-invasive imaging. Based on the hypothesis that the systemic circulation is reflected in retinal vessels, we investigated if coronary artery
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368f2b2715a85bb82fa67e83be4dad6a
https://doi.org/10.1111/aos.14444
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7
Nitric oxide (NO) synthase but not NO, HNO or H
Autor: Maximilian, Matthies, Kristoffer, Rosenstand, Inger, Nissen, Stan, Muitjens, Lars P, Riber, Jo G R, De Mey, Maria, Bloksgaard
Publikováno v: British journal of pharmacologyREFERENCES. 179(5)
Superoxide anions can reduce the bioavailability and actions of endothelium-derived NO. In human resistance-sized arteries, endothelium-dependent vasodilatation can be mediated by HSmall arteries were isolated from biopsies of the parietal pericardiu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::faf70511601b2c684eee636c342d316f
https://pubmed.ncbi.nlm.nih.gov/34664280
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8
Neutral endopeptidase inhibitors blunt kidney fibrosis by reducing myofibroblast formation
Autor: Jacques M.G.J. Duijs, Dania Reiche, Jerzy Adamski, Ton J. Rabelink, Cornelia Prehn, Jennifer Veth, Roel Bijkerk, Marina A. Aleksinskaya, Jo G. R. De Mey, Bettina Husen, Anton Jan van Zonneveld
Publikováno v: Clinical Science, 133(2), 239-252. Portland Press Ltd.
Bijkerk, R, Aleksinskaya, M A, Duijs, J M G J, Veth, J, Husen, B, Reiche, D, Prehn, C, Adamski, J, Rabelink, T J, De Mey, J G R & van Zonneveld, A J 2019, ' Neutral endopeptidase inhibitors blunt kidney fibrosis by reducing myofibroblast formation ', Clinical Science, vol. 133, no. 2, pp. 239-252 . https://doi.org/10.1042/CS20180882
Kidney fibrosis is the common pathophysiological mechanism in end-stage renal disease characterized by excessive accumulation of myofibroblast-derived extracellular matrix. Natriuretic peptides have been demonstrated to have cyclic guanosine monophos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81faab805c728d406474cc71f5af6e3f
https://doi.org/10.1042/cs20180882
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9
Akademický článek
Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice.
Autor: Ramesh Chennupati, Merlijn J P M T Meens, Vincent Marion, Ben J Janssen, Wouter H Lamers, Jo G R De Mey, S Eleonore Köhler
Publikováno v: PLoS ONE, Vol 9, Iss 7, p e102264 (2014)
Argininosuccinate synthetase (ASS) is essential for recycling L-citrulline, the by-product of NO synthase (NOS), to the NOS substrate L-arginine. Here, we assessed whether disturbed arginine resynthesis modulates endothelium-dependent vasodilatation
Externí odkaz: https://doaj.org/article/84224269fcdb4318b5c33f291ce9fdb4
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