Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jo Erika Ciccotelli"'
Publikováno v:
The Journal of Immunology. 194:214.5-214.5
We have recently developed a novel vaccine strategy that involves conjugating antigens to polyguanine sequences to fabricate aggregated particulates with exposed scavenger receptor ligands for in vivo targeting to antigen presenting cells. We have pr
Autor:
Helene Toussaint, Jo Erika Ciccotelli, Geza Erdos, Cara Carey, Simon Watkins, Adriana Larregina, Louis Falo
Publikováno v:
The Journal of Immunology. 192:111.11-111.11
The efficacy of current vaccines results from the induction of protective antibodies. However we still lack efficacious vaccines against many infectious agents that require durable and protective T cell immunity. Efficient and selective delivery of a
Publikováno v:
The Journal of Immunology. 192:111.12-111.12
Effective vaccine design depends on the ability to target specific antigens to antigen presenting cells (APCs), including dendritic cells (DCs). Conjugation of proteins antigens to polyguanine (Poly(dG)) molecules is a novel immunization approach cap