Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol

Autor: Gerhardt Attard, Laura Murphy, Noel W Clarke, William Cross, Robert J Jones, Christopher C Parker, Silke Gillessen, Adrian Cook, Chris Brawley, Claire L Amos, Nafisah Atako, Cheryl Pugh, Michelle Buckner, Simon Chowdhury, Zafar Malik, J Martin Russell, Clare Gilson, Hannah Rush, Jo Bowen, Anna Lydon, Ian Pedley, Joe M O'Sullivan, Alison Birtle, Joanna Gale, Narayanan Srihari, Carys Thomas, Jacob Tanguay, John Wagstaff, Prantik Das, Emma Gray, Mymoona Alzoueb, Omi Parikh, Angus Robinson, Isabel Syndikus, James Wylie, Anjali Zarkar, George Thalmann, Johann S de Bono, David P Dearnaley, Malcolm D Mason, Duncan Gilbert, Ruth E Langley, Robin Millman, David Matheson, Matthew R Sydes, Louise C Brown, Mahesh K B Parmar, Nicholas D James, Elin Jones, Katherine Hyde, Hilary Glen, Sarah Needleman, Ursula McGovern, Denise Sheehan, Sangeeta Paisey, Richard Shaffer, Mark Beresford, Emilio Porfiri, David Fackrell, Ling Lee, Thiagarajan Sreenivasan, Sue Brock, Simon Brown, Amit Bahl, Mike Smith-Howell, Cathryn Woodward, Mau-Don Phan, Danish Mazhar, Krishna Narahari, Fiona Douglas, Anil Kumar, Abdel Hamid, Azman Ibrahim, Dakshinamoorthy Muthukumar, Matthew Simms, Jane Worlding, Anna Tran, Mohammed Kagzi, Carmel Pezaro, Virgil Sivoglo, Benjamin Masters, Pek Keng-Koh, Caroline Manetta, Duncan McLaren, Nishi Gupta, Stergios Boussios, Henry Taylor, John Graham, Carla Perna, Lucinda Melcher, Warren Grant, Ami Sabharwal, Uschi Hofmann, Robert Dealey, Neil McPhail, Robert Brierly, Lisa Capaldi, Norma Sidek, Peter Whelan, Peter Robson, Alison Falconer, Sarah Rudman, Sindu Vivekanandan, Vinod Mullessey, Maria Vilarino-Varela, Vincent Khoo, Karen Tipples, Mehran Afshar, Patryk Brulinski, Vijay Sangar, Clive Peedell, Ashraf Azzabi, Peter Hoskin, Viwod Mullassery, Santhanam Sundar, Yakhub Khan, Ruth Conroy, Andrew Protheroe, Judith Carser, Paul Rogers, Kathryn Tarver, Stephanie Gibbs, Mohammad Muneeb Khan, Mohan Hingorani, Simon Crabb, Manal Alameddine, Neeraj Bhalla, Robert Hughes, John Logue, Darren Leaning, Salil Vengalil, Daniel Ford, Georgina Walker, Ahmed Shaheen, Omar Khan, Andrew Chan, Imtiaz Ahmed, Serena Hilman, Ian Sayers, Ashok Nikapota, David Bloomfield, Tim Porter, Joji Joseph, Cyrill Rentsch, Ricardo Pereira Mestre, Enrico Roggero, Jörg Beyer, Markus Borner, Raeto Strebel, Dominik Berthold, Daniel Engeler, Hubert John, Razvan Popescu, Donat Durr

Publikováno v: Attard, Gerhardt; Murphy, Laura; Clarke, Noel W; Cross, William; Jones, Robert J; Parker, Christopher C; Gillessen, Silke; Cook, Adrian; Brawley, Chris; Amos, Claire L; Atako, Nafisah; Pugh, Cheryl; Buckner, Michelle; Chowdhury, Simon; Malik, Zafar; Russell, J Martin; Gilson, Clare; Rush, Hannah; Bowen, Jo; Lydon, Anna; ... (2022). Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol. The lancet, 399(10323), pp. 447-460. Elsevier 10.1016/S0140-6736(21)02437-5
Systemic Therapy in Advancing or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators 2022, ' Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol ', Lancet (London, England), vol. 399, no. 10323, pp. 447-460 . https://doi.org/10.1016/S0140-6736(21)02437-5

BACKGROUND Men with high-risk non-metastatic prostate cancer are treated with androgen-deprivation therapy (ADT) for 3 years, often combined with radiotherapy. We analysed new data from two randomised controlled phase 3 trials done in a multiarm, mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07768ca840f38b8ba6462bcfaa787f1

Managing Asbestos-Containing Materials in the Built Environment: Report of a Health and Safety Executive and Government Office for Science Workshop

Autor: Laurie S. T. Davies, Garry John Burdett, Jo Bowen, Christopher Michael Barber

Publikováno v: Annals of Work Exposures and Health. 61:16-21

The duty to manage asbestos in non-domestic premises is described in the Control of Asbestos Regulations 2012. Health and Safety Executive (HSE) policy and guidance on asbestos in the built environment in Great Britain is that asbestos-containing mat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821c71eaca32f2c8098ffa0c0b207d1e
https://doi.org/10.1093/annweh/wxw007

Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy

Autor: Joanna Gale, C.L. Ferguson, J. Martin Russell, Prabir Chakraborti, Carys Thomas, Mohan Hingorani, Joe M. O'Sullivan, Anjali Zarkar, Clare Gilson, Zafar Malik, John Wagstaff, Jo Bowen, Fiona McKinna, Angus Robinson, Claire Amos, Simon Chowdhury, Alison Birtle, Fawzi Adab, Peter Hoskin, San Aung, Robin Millman, Chris Parker, Neil McPhail, Alastair W. S. Ritchie, Robert Jones, Jason F. Lester, Noel W. Clarke, Susannah Brock, Gerhardt Attard, Andrew Protheroe, James D. Wylie, Omi Parikh, Johann S. de Bono, Nicholas D. James, Julian Money-Kyrle, Malcolm David Mason, William Cross, Emma Gray, David Matheson, Dominik Berthold, Silke Gillessen, Melissa R. Spears, David P. Dearnaley, Narayanan Srihari, Matthew R. Sydes, Mahesh K.B. Parmar, Chris Brawley

Publikováno v: STAMPEDE investigators 2017, ' Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy ', New England Journal of Medicine, vol. 377, no. 4, pp. 338-351 . https://doi.org/10.1056/NEJMoa1702900
STAMPEDE Investigators & Gillessen, S 2017, ' Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy ', The New England Journal of Medicine, vol. 377, no. 4, pp. 338-351 . https://doi.org/10.1056/NEJMoa1702900
The New England journal of medicine, vol. 377, no. 4, pp. 338-351

BACKGROUND: Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate cancer. We assessed the effect of this combination in men starting long-term androgen-deprivation therapy (ADT), using a multigroup, multistage trial de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae654176b4379045bb5aaa6609f18434
https://pure.qub.ac.uk/en/publications/bca063cc-7a5e-46eb-95d8-7e27f2cf88b6

Is there an opportunity to reduce urinary catheter-related infections? Exploring variation in catheterisation rates in care homes

Autor: Jo Bowen, A. Brady, K. Gunn, Gillian Smith, T. Ejidokun, D. S. Tompkins, Cliodna A. M. McNulty, Elaine Freeman, Chris Foy, Ian P. Donald

Publikováno v: British Journal of Infection Control. 7:22-28

rinary catheterisation in care homes is associated with increased morbidity, hospitalisation and mortality. The authors aimed to determine whether staffing, resident underlying illness or nursing band, or use of other toileting methods were responsib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b421315c582b9cccc76d94a3ab290b4
https://doi.org/10.1177/14690446060070010701

The Triggering Hypothesis of the Role of Life Events in Schizophrenia

Autor: Steven R. Hirsch, Jo Bowen, Philip Cramer

Publikováno v: British Journal of Psychiatry. 161:84-87

The idea of a triggering effect in schizophrenia emphasises the role of life events as precipitating factors which act on an individual's specific predisposition towards the illness (Wing, 1978).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ef9f6418afc2590f5c8e68b063d005
https://doi.org/10.1192/s0007125000297092