Zobrazeno 1 - 10
of 19 772
pro vyhledávání: '"Jo Anne"'
Autor:
Sienna S. Drake, Aliyah Zaman, Christine Gianfelice, Elizabeth M.-L. Hua, Kali Heale, Elia Afanasiev, Wendy Klement, Jo Anne Stratton, Alexandre Prat, Stephanie Zandee, Alyson E. Fournier
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background The role of senescence in disease contexts is complex, however there is considerable evidence that depletion of senescent cells improves outcomes in a variety of contexts particularly related to aging, cognition, and neurodegenera
Externí odkaz:
https://doaj.org/article/07e09c6af8784c0bbef1de4e6dc3cbe6
Autor:
Yana Kibalnyk, Elia Afanasiev, Ronan M. N. Noble, Adrianne E. S. Watson, Irina Poverennaya, Nicole L. Dittmann, Maria Alexiou, Kara Goodkey, Amanda A. Greenwell, John R. Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L. Bourque, Jo Anne Stratton, Anastassia Voronova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract ANKRD11 (Ankyrin Repeat Domain 11) is a chromatin regulator and a causative gene for KBG syndrome, a rare developmental disorder characterized by multiple organ abnormalities, including cardiac defects. However, the role of ANKRD11 in heart
Externí odkaz:
https://doaj.org/article/ce8c90516c504572ba5ad45d0a89daf1
Autor:
Liam Hodgson, Yue Li, Yasser Iturria-Medina, Jo Anne Stratton, Guy Wolf, Smita Krishnaswamy, David A. Bennett, Danilo Bzdok
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Late onset Alzheimer’s disease (AD) is a progressive neurodegenerative disease, with brain changes beginning years before symptoms surface. AD is characterized by neuronal loss, the classic feature of the disease that underlies brain atrop
Externí odkaz:
https://doaj.org/article/7d8c85b5304d4fe2a88eedbabca21c21
Autor:
Marie-France Dorion, Diana Casas, Irina Shlaifer, Moein Yaqubi, Peter Fleming, Nathan Karpilovsky, Carol X.-Q. Chen, Michael Nicouleau, Valerio E. C. Piscopo, Emma J. MacDougall, Aeshah Alluli, Taylor M. Goldsmith, Alexandria Schneider, Samuel Dorion, Nathalia Aprahamian, Adam MacDonald, Rhalena A. Thomas, Roy W. R. Dudley, Jeffrey A. Hall, Edward A. Fon, Jack P. Antel, Jo Anne Stratton, Thomas M. Durcan, Roberta La Piana, Luke M. Healy
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Background Induced pluripotent stem cell-derived microglia (iMGL) represent an excellent tool in studying microglial function in health and disease. Yet, since differentiation and survival of iMGL are highly reliant on colony-stimulating fac
Externí odkaz:
https://doaj.org/article/aa6be16cdc4045c0b1747096bb52aa8a
Publikováno v:
Cogent Psychology, Vol 11, Iss 1 (2024)
AbstractObjective Increasing number of depression cases, drug tolerability and compliance issues have triggered researchers to actively seek potential alternative treatment modalities. Integrating traditional Chinese medicine (TCM) and Western medici
Externí odkaz:
https://doaj.org/article/0ca10ea6004f4fe7a27d0b84cdff4b8b
Autor:
Werner T. Flueck, Jo Anne M. Smith-Flueck, Miguel E. Escobar, Melina E. Zuliani, Beat Fuchs, James R. Heffelfinger, Patricia Black-Decima, Zygmunt Gizejewski, Fernando Vidal, Javier Barrio, Silvina M. Molinuevo, Adrian J. Monjeau, Stefan Hoby, Jaime E. Jiménez
Publikováno v:
Conservation, Vol 3, Iss 4, Pp 569-594 (2023)
Conservation strategies for huemul (Hippocamelus bisulcus), listed as an endangered cervid by IUCN, have not helped to reverse its declining population trends. Recent evaluations of historical data revealed that they also inhabited lower valleys and
Externí odkaz:
https://doaj.org/article/9124582510ed487b9b91a536c5733498
Autor:
Lovatiana Andriamboavonjy, Adam MacDonald, Laura K. Hamilton, Marjorie Labrecque, Marie-Noёlle Boivin, Jason Karamchandani, Jo Anne Stratton, Martine Tetreault
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Preserving the in vivo cell transcriptome is essential for accurate profiling, yet factors during cell isolation including time ex vivo and temperature induce artifactual gene expression, particularly in stress-responsive immune cells. In th
Externí odkaz:
https://doaj.org/article/d5c5c58582384d829b016e2e2d948c81
Autor:
Chao Weng, Adam M.R. Groh, Moein Yaqubi, Qiao-Ling Cui, Jo Anne Stratton, G. R. Wayne Moore, Jack P. Antel
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 5, Pp 1336-1349 (2025)
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system. Recent evidence has challenged the classical view of the functionally static mature oligodendroc
Externí odkaz:
https://doaj.org/article/e0be70ed53e9484c8f42390661cc299e
Publikováno v:
Sensors, Vol 24, Iss 14, p 4520 (2024)
Particulate matter of 2.5 µm and smaller (PM2.5) is known to cause many respiratory health problems, such as asthma and heart disease. A primary source of PM2.5 is emissions from cars, trucks, and buses. Emissions from university transit bus systems
Externí odkaz:
https://doaj.org/article/4ca2bdc87f464172b5966df03449527d
Autor:
Milton Guilherme Forestieri Fernandes, Abdulshakour Mohammadnia, Florian Pernin, Laura Eleonora Schmitz-Gielsdorf, Caroline Hodgins, Qiao-Ling Cui, Moein Yaqubi, Manon Blain, Jeffery Hall, Roy Dudley, Myriam Srour, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Jo Anne Stratton, Moses Rodriguez, Tanja Kuhlmann, Wayne Moore, Timothy E. Kennedy, Jack P. Antel
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Oligodendrocyte (OL) injury and loss are central features of evolving lesions in multiple sclerosis. Potential causative mechanisms of OL loss include metabolic stress within the lesion microenvironment. Here we use the injury response of pr
Externí odkaz:
https://doaj.org/article/0b83309164e245e4aea64f44e59886dc