Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jo Anna Robinson"'
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
Autor:
Liang Zhang, Daniel J. Griffin, Matthew G. Beaver, Laura E. Blue, Christopher J. Borths, Derek B. Brown, Seb Caille, Ying Chen, Alan H. Cherney, Brian M. Cochran, John T. Colyer, Michael T. Corbett, Tiffany L. Correll, Richard D. Crockett, Xi-Jie Dai, Peter K. Dornan, Robert P. Farrell, Simon J. Hedley, Hsiao-Wu Hsieh, Liang Huang, Seth Huggins, Min Liu, Michael A. Lovette, Kyle Quasdorf, William Powazinik, Jonathan Reifman, Jo Anna Robinson, Rahul P. Sangodkar, Sonika Sharma, Srividya Sharvan Kumar, Austin G. Smith, Gabrielle St-Pierre, Jason S. Tedrow, Oliver R. Thiel, Jonathan V. Truong, Shawn D. Walker, Carolyn S. Wei, Ashraf Wilsily, Yong Xie, Ning Yang, Andrew T. Parsons
Publikováno v:
Organic Process Research & Development. 26:3115-3125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::972bf6936d6ce0633f15e7dda136b897
https://doi.org/10.1021/acs.oprd.2c00249
https://doi.org/10.1021/acs.oprd.2c00249
Autor:
Pablo Rolandi, Ayman Allian, Andrew J. Maloney, Seth Huggins, Lauren R. Graham, Jo Anna Robinson, Dongying Erin Shen, Roger Hart, Richard D. Braatz, Xiaoxiang Zhu, Matthew G. Beaver, Shawn D. Walker, Elçin Içten
Publikováno v:
Organic Process Research & Development. 24:1861-1875
This manuscript details process characterization efforts and the development of corresponding process models to inform a process control strategy to produce a carfilzomib drug substance intermediat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7760fcb8f3cf26d55f21aa244e35f3f9
https://doi.org/10.1021/acs.oprd.0c00187
https://doi.org/10.1021/acs.oprd.0c00187
Autor:
Jo Anna Robinson, Andrew T. Parsons, Seth Huggins, Matthew G. Beaver, Ayman Allian, Xiaoxiang Zhu, Andrew J. Maloney, Roger Hart, Richard D. Braatz, Dongying Erin Shen, Pablo Rolandi, Elçin Içten, Shawn D. Walker
Publikováno v:
Organic Process Research & Development. 24:1876-1890
This article details efforts to characterize and develop a process control strategy for the manufacture of enone 2, a carfilzomib drug substance intermediate obtained through a Barbier-type Grignar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1442d112e97263422f251d8726d3eec7
https://doi.org/10.1021/acs.oprd.0c00188
https://doi.org/10.1021/acs.oprd.0c00188
Autor:
Jo Anna Robinson, Ayman Allian, Jan Riedel, Michael T. Corbett, Kyle D. Baucom, Wendy Chen, Sheng Cui, Derek B. Brown, Elçin Içten, Parth Patel, Michael A. Lovette, Matthew G. Beaver, Tawnya G. Flick, Alicia Zeng, Xianqing Shi, Ning Yang, Andrew T. Parsons, Shawn D. Walker
Publikováno v:
Organic Process Research & Development. 24:490-499
The development and kilogram-scale demonstration of an improved process for the synthesis of the epoxyketone warhead of carfilzomib is described. Critical to the success of this process was: (1) de...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d7594e430e4b5cdc5fe59d563447ea
https://doi.org/10.1021/acs.oprd.0c00052
https://doi.org/10.1021/acs.oprd.0c00052
Autor:
Ying Chen, Baburaj Krishnan, Lokesh Pawar, Jason S. Tedrow, Ramesh Jayaramaiah, Jo Anna Robinson, Andrew T. Parsons, Athimoolam Arunachalampillai
Publikováno v:
Tetrahedron. 75:4266-4270
The development of a phase-appropriate manufacturing-scale synthesis of potassium 2-fluoro-6-hydroxyphenyltrifluoroborate was achieved. Investigations into improving the yield and robustness indicated that pH of the reaction medium is a critical proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc67b8131836bf6b34e50227cf33a64
https://doi.org/10.1016/j.tet.2019.05.063
https://doi.org/10.1016/j.tet.2019.05.063
Autor:
Donkin, Christine
Publikováno v:
Wildlife Australia; Autumn2021, Vol. 58 Issue 1, p20-21, 2p, 2 Color Photographs
Publikováno v:
Wildlife Australia; Autumn2021, Vol. 58 Issue 1, p22-22, 1p, 2 Color Photographs
Autor:
Edward P. Sarafino, Lorelle J. Burton
Custom E-Text of: Health Psychology: Biopsychosocial Interactions, 8th Edition Sarafino draws from the research and theory of many disciplines in order to show psychologists how psychology and health affect each other. Health Psychology: Biopsychoso
Building on the success of the market-leading and award-winning previous editions, Psychology: 4th Australian and New Zealand Edition has been thoroughly updated to provide comprehensive coverage of contemporary local and international data, research
Autor:
Edward P. Sarafino
Custom E-Text of: Health Psychology: Biopsychosocial Interactions, 8th Edition Sarafino draws from the research and theory of many disciplines in order to show psychologists how psychology and health affect each other. Health Psychology: Biopsychoso