Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jo A. Oostveen"'
Publikováno v:
Journal of Neuroscience Research. 53:66-77
Transgenic mice that overexpress a mutated human CuZn superoxide dismutase (SOD1) gene (gly93-->ala) found in some patients with familial ALS (FALS) have been shown to develop motor neuron disease, as evidenced by motor neuron loss in the lumbar and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a516d9d499cbf54412377c234caec7
https://doi.org/10.1002/(sici)1097-4547(19980701)53:1<66::aid-jnr7>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19980701)53:1<66::aid-jnr7>3.0.co
Publikováno v:
Brain Research. 798:325-329
Recent studies have demonstrated the neuroprotective properties of the novel imidazoquinoline benzodiazepine receptor partial agonist, PNU-101017, in the gerbil forebrain ischemia model. The compound effectively reduces delayed post-ischemic (5 min b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570c66c0c295a7439f3b022d0fd49254
https://doi.org/10.1016/s0006-8993(98)00478-8
https://doi.org/10.1016/s0006-8993(98)00478-8
Publikováno v:
Glia. 23:249-256
Transgenic mice that highly over-express a mutated human CuZn superoxide dismutase (SOD1) gene [gly93-->ala; TgN(SOD1-G93A)G1H line] found in some patients with familial ALS (FALS) have been shown to develop motor neuron disease that is characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7249a93efa3a74dcac869ce27b04530c
https://doi.org/10.1002/(sici)1098-1136(199807)23:3<249::aid-glia7>3.0.co
https://doi.org/10.1002/(sici)1098-1136(199807)23:3<249::aid-glia7>3.0.co
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 18:539-547
A brief period of bilateral carotid occlusion (BCO)-induced forebrain ischemia in gerbils triggers neuronal degeneration and the subsequent expression of amyloid precursor protein (APP), b-amyloid protein (b-AP), and apolipoprotein E (APO-E) in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371e71fd5dea7c15e99cbc1d73da1ba3
https://doi.org/10.1097/00004647-199805000-00009
https://doi.org/10.1097/00004647-199805000-00009
Publikováno v:
Journal of Neuroscience Methods. 76:115-122
The investigation of oxygen radical-induced lipid peroxidative neuronal damage in the context of acute and chronic neurodegenerative disorders has been largely limited to the use of ex vivo analytical methodologies. These are often fraught with sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4d84fda3f93a15d1a8b05c76f2908d
https://doi.org/10.1016/s0165-0270(97)00089-7
https://doi.org/10.1016/s0165-0270(97)00089-7
Autor:
Paula K. Andrus, Donald B. Carter, Jo A. Oostveen, E. Jon Jacobsen, Edward D. Hall, Timothy J. Fleck
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 17:875-883
PNU-101017 is a novel, imidazoquinoline amide and benzodiazepine receptor partial agonist that has high affinity for the GABAA receptor subtypes containing the alpha 1 and alpha 3 or alpha 5 subunits. At each of these receptors, the compound is a par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892804491446983e1972ade6559df0a3
https://doi.org/10.1097/00004647-199708000-00006
https://doi.org/10.1097/00004647-199708000-00006
Publikováno v:
Neuroscience Letters. 228:45-49
The neuroprotective effects of U-101017, [7-chloro-5-[cis-3,5-dimethylpiperazine)carbonyl]-imidazole[1,5a]quinoli ne-3-carboxylate], a GABA(A) receptor partial agonist, were investigated in 3-acetylpyridine (3-AP) treated Wistar rats. A significant (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1bbb547cbd63d9b1c874804a2e97c2
https://doi.org/10.1016/s0304-3940(97)00353-4
https://doi.org/10.1016/s0304-3940(97)00353-4
Publikováno v:
Journal of Neuroscience Research. 47:650-654
A 10-min period of bilateral carotid occlusion (BCO)-induced forebrain ischemia in gerbils triggers a delayed retrograde degeneration of 35-40% of dopaminergic nigrostriatal (NS) neurons. The mechanism of the NS degeneration is believed to involve ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6149767295be666ed0438d6e6d9ac85
https://doi.org/10.1002/(sici)1097-4547(19970315)47:6<650::aid-jnr11>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19970315)47:6<650::aid-jnr11>3.0.co
Publikováno v:
Brain Research. 738:172-175
Studies were conducted to determine if treatment of mice with methamphetamine (METH) would produce a loss of dopaminergic cells in the substantia nigra. The number of TH+/Nissl-stained was significantly decreased in both Swiss-Webster (S-W) and C57bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19751d5a86fa41ddc982b813593ccd8
https://doi.org/10.1016/0006-8993(96)00995-x
https://doi.org/10.1016/0006-8993(96)00995-x
Publikováno v:
Journal of Neuroscience Research. 44:293-299
The purpose of this study was to investigate the role of oxygen radical-induced lipid peroxidative mechanisms in trophic deprivation-induced apoptotic motor neuronal degeneration by testing the ability of the 21-aminosteroid lipid peroxidation inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494d1effd0f5f0d6c8aed64b8632ef7d
https://doi.org/10.1002/(sici)1097-4547(19960501)44:3<293::aid-jnr10>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19960501)44:3<293::aid-jnr10>3.0.co