Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Jörg Hennenlotter"'
Autor:
Naomi Hoenisch Gravel, Annika Nelde, Jens Bauer, Lena Mühlenbruch, Sarah M. Schroeder, Marian C. Neidert, Jonas Scheid, Steffen Lemke, Marissa L. Dubbelaar, Marcel Wacker, Anna Dengler, Reinhild Klein, Paul-Stefan Mauz, Hubert Löwenheim, Mathias Hauri-Hohl, Roland Martin, Jörg Hennenlotter, Arnulf Stenzl, Jonas S. Heitmann, Helmut R. Salih, Hans-Georg Rammensee, Juliane S. Walz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract T cell recognition of human leukocyte antigen (HLA)-presented tumor-associated peptides is central for cancer immune surveillance. Mass spectrometry (MS)-based immunopeptidomics represents the only unbiased method for the direct identificati
Externí odkaz:
https://doaj.org/article/dbea2b72e80845b88f66d5852cf7b946
Autor:
Florian A. Büttner, Stefan Winter, Viktoria Stühler, Steffen Rausch, Jörg Hennenlotter, Susanne Füssel, Stefan Zastrow, Matthias Meinhardt, Marieta Toma, Carmen Jerónimo, Rui Henrique, Vera Miranda-Gonçalves, Nils Kröger, Silvia Ribback, Arndt Hartmann, Abbas Agaimy, Christine Stöhr, Iris Polifka, Falko Fend, Marcus Scharpf, Eva Comperat, Gabriel Wasinger, Holger Moch, Arnulf Stenzl, Marco Gerlinger, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Renal cell carcinoma (RCC) is a heterogeneous disease comprising histologically defined subtypes. For therapy selection, precise subtype identification and individualized prognosis are mandatory, but currently limited. Our aim was
Externí odkaz:
https://doaj.org/article/876bc134c9284335b9606279982c1274
Autor:
Anna Reustle, Lena‐Sophie Menig, Patrick Leuthold, Ute Hofmann, Viktoria Stühler, Christian Schmees, Michael Becker, Mathias Haag, Verena Klumpp, Stefan Winter, Florian A. Büttner, Steffen Rausch, Jörg Hennenlotter, Falko Fend, Marcus Scharpf, Arnulf Stenzl, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Abstract Background The metabolic enzyme nicotinamide‐N‐methyltransferase (NNMT) is highly expressed in various cancer entities, suggesting tumour‐promoting functions. We systematically investigated NNMT expression and its metabolic interaction
Externí odkaz:
https://doaj.org/article/9033f25c01264368bb3a1e6cc5f4da53
Autor:
Olga Katzendorn, Inga Peters, Natalia Dubrowinskaja, Hossein Tezval, Pouriya Faraj Tabrizi, Christoph A. von Klot, Jörg Hennenlotter, Marcel Lafos, Markus A. Kuczyk, Jürgen Serth
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background DNA methylation is frequently observed in the development and progression of many human tumors as well as renal cell cancer (RCC). Tumor Associated Calcium Signal Transducer 2 (TACSTD2) participates in cell cycle progression throu
Externí odkaz:
https://doaj.org/article/177404d0eda24c7eb89204fddace0e08
Autor:
Anna Reustle, Moreno Di Marco, Carolin Meyerhoff, Annika Nelde, Juliane S. Walz, Stefan Winter, Siahei Kandabarau, Florian Büttner, Mathias Haag, Linus Backert, Daniel J. Kowalewski, Steffen Rausch, Jörg Hennenlotter, Viktoria Stühler, Marcus Scharpf, Falko Fend, Arnulf Stenzl, Hans-Georg Rammensee, Jens Bedke, Stefan Stevanović, Matthias Schwab, Elke Schaeffeler
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-24 (2020)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the dominant subtype of renal cancer. With currently available therapies, cure of advanced and metastatic ccRCC is achieved only in rare cases. Here, we developed a workflow integrating d
Externí odkaz:
https://doaj.org/article/fc55be784afc4fe685c251765eeb65fb
Autor:
Olga Katzendorn, Christoph A J von Klot, Samy Mahjoub, Pouriya Faraj Tabrizi, Nina N Harke, Hossein Tezval, Susanne Hellms, Jörg Hennenlotter, Mirza S Baig, Arnulf Stenzl, Ferdinand Seith, Marcel Lafos, Markus A Kuczyk, Steffen Rausch, Inga Peters
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0271981 (2022)
Available tests to detect clinically significant prostate cancer frequently lead to overdiagnosis and overtreatment. Our study assessed the feasibility of combining a urinary biomarker-based risk score (SelectMDx®) and multiparametric MRI outcomes i
Externí odkaz:
https://doaj.org/article/ceafe639f0a740e79b64ecad149effb7
Autor:
Florian Büttner, Stefan Winter, Steffen Rausch, Jörg Hennenlotter, Stephan Kruck, Arnulf Stenzl, Marcus Scharpf, Falko Fend, Abbas Agaimy, Arndt Hartmann, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Stratification of cancer patients to identify those with worse prognosis is increasingly important. Through in silico analyses, we recently developed a gene expression-based prognostic score (S3-score) for clear cell renal cell ca
Externí odkaz:
https://doaj.org/article/00af67f98dc240ff8d5d4c9a28736064
Autor:
Stefan Zoltán Lutz, Jörg Hennenlotter, Marcus Oliver Scharpf, Corinna Sailer, Louise Fritsche, Vera Schmid, Konstantinos Kantartzis, Robert Wagner, Rainer Lehmann, Lucia Berti, Andreas Peter, Harald Staiger, Andreas Fritsche, Falko Fend, Tilman Todenhöfer, Arnulf Stenzl, Hans-Ulrich Häring, Martin Heni
Publikováno v:
Molecular Metabolism, Vol 8, Iss , Pp 158-166 (2018)
Objective: While prostate cancer does not occur more often in men with diabetes, survival is markedly reduced in this patient group. Androgen signaling is a known and major driver for prostate cancer progression. Therefore, we analyzed major componen
Externí odkaz:
https://doaj.org/article/4a1bfcb50401442287247dc28d054760
Autor:
Andras Franko, Lucia Berti, Jörg Hennenlotter, Steffen Rausch, Marcus O. Scharpf, Martin Hrabĕ de Angelis, Arnulf Stenzl, Andreas Peter, Andreas L. Birkenfeld, Stefan Z. Lutz, Hans-Ulrich Häring, Martin Heni
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 507 (2020)
Type 2 diabetes (T2D) is associated with worse prognosis of prostate cancer (PCa). The molecular mechanisms behind this association are still not fully understood. The aim of this study was to identify key factors, which contribute to the more aggres
Externí odkaz:
https://doaj.org/article/22a14e7c823d4434a0348f20eed5a1c1
Autor:
Anja von Au, Matthaeus Vasel, Sabrina Kraft, Carla Sens, Norman Hackl, Alexander Marx, Philipp Stroebel, Jörg Hennenlotter, Tilman Todenhöfer, Arnulf Stenzl, Sarah Schott, Hans-Peter Sinn, Antoinette Wetterwald, Justo Lorenzo Bermejo, Marco G Cecchini, Inaam A Nakchbandi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 8, Pp 925-938 (2013)
Fibronectin is ubiquitously expressed in the extracellular matrix, and experimental evidence has shown that it modulates blood vessel formation. The relative contribution of local and circulating fibronectin to blood vessel formation in vivo remains
Externí odkaz:
https://doaj.org/article/1bd397fdc23c48fda9dccebf2d503938