Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jörg H. Leupold"'
Publikováno v:
BioTechniques, Vol 37, Iss 6, Pp 940-946 (2004)
The chick embryonic metastasis (CEM) assay is a fast in vivo method to investigate the invasive properties of tumor cells. Until now, most quantification methods were semiquantitative and time-consuming. Here we describe a rapid quantification method
Externí odkaz:
https://doaj.org/article/afa371fefa094f21a6124fd706fc3ffc
Autor:
Heike Allgayer, Stefan Post, Ernst Lengyel, Gabriele D. Maurer, Irfan Asangani, Jörg H. Leupold
The urokinase receptor [urokinase plasminogen activator receptor (u-PAR)] promotes invasion and metastasis and is associated with poor patient survival. Recently, it was shown that Src induces u-PAR gene expression via Sp1 bound to the u-PAR promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b1fa7feaaffdc02f67031151a65320
https://doi.org/10.1158/1541-7786.c.6542805
https://doi.org/10.1158/1541-7786.c.6542805
Autor:
Heike Allgayer, Stefan Post, Ernst Lengyel, Gabriele D. Maurer, Irfan Asangani, Jörg H. Leupold
Supplementary Figures S1-S2; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1495fcff1487f756ce724a863584c72e
https://doi.org/10.1158/1541-7786.22520841.v1
https://doi.org/10.1158/1541-7786.22520841.v1
Autor:
Heike Allgayer, Stefan Fruehauf, W. Jens Zeller, Frederik Wenz, Jörg H. Leupold, Marcus J. Trunk, Jonathan P. Sleeman, Li Li, Stephanie Laufs, Patrick Maier, Doreen Heckmann
PDF file 129K, S6: Confirmation of expression of microRNAs and putative target genes in SW480wildtype, SW480CXCR4, SW480CXCR7, and SW480CXCR4/CXCR7 cells treated with SDF-1a for 0, 3 and 12 h by qPCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d049bf80a80695b6f67723b7554ca2
https://doi.org/10.1158/1078-0432.22448868.v1
https://doi.org/10.1158/1078-0432.22448868.v1
Autor:
Heike Allgayer, Stefan Fruehauf, W. Jens Zeller, Frederik Wenz, Jörg H. Leupold, Marcus J. Trunk, Jonathan P. Sleeman, Li Li, Stephanie Laufs, Patrick Maier, Doreen Heckmann
Purpose: In colorectal cancer, increased expression of the CXC chemokine receptor 4 (CXCR4) has been shown to provoke metastatic disease due to the interaction with its ligand stromal cell-derived factor-1 (SDF-1). Recently, a second SDF-1 receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e800917f809f32f97df492e5e799dbc
https://doi.org/10.1158/1078-0432.c.6521499.v1
https://doi.org/10.1158/1078-0432.c.6521499.v1
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613498
The CAM model enables an in vivo analysis of the individual sub-steps of the metastatic cascade like local invasion, intravasation, or the establishment of metastasis in particular organs. Incubated fertilized chicken eggs are inoculated with human t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5092adde115d1d215732be650397f427
https://doi.org/10.1007/978-1-0716-1350-4_2
https://doi.org/10.1007/978-1-0716-1350-4_2
Autor:
Santoshi Muppala, Giridhar Mudduluru, Jörg H Leupold, Daniel Buergy, Jonathan P Sleeman, Heike Allgayer
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59563 (2013)
Cancer is a complex disease process that evolves as a consequence of multiple malfunctions in key regulatory molecular networks. Understanding these networks will be essential to combat cancer. In this study, we focussed on central players in such ne
Externí odkaz:
https://doaj.org/article/e4044d4f17184f569fa1b41ec5c232c7
Publikováno v:
Advances in experimental medicine and biology. 1277
The tumor microenvironment (TME) is decisive for the eradication or survival of any tumor mass. Moreover, it plays a pivotal role for metastasis and for providing the metastatic niche. The TME offers special physiological conditions and is composed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15a3f59e7cfa86437162e7f69349190b
https://pubmed.ncbi.nlm.nih.gov/33119862
https://pubmed.ncbi.nlm.nih.gov/33119862
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030502232
The tumor microenvironment (TME) is decisive for the eradication or survival of any tumor mass. Moreover, it plays a pivotal role for metastasis and for providing the metastatic niche. The TME offers special physiological conditions and is composed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b5fa0503ab616889ce26bace6c1349
https://doi.org/10.1007/978-3-030-50224-9_1
https://doi.org/10.1007/978-3-030-50224-9_1
Autor:
Marcel Klingenberg, Thilo Miersch, Heike Allgayer, Jörg H. Leupold, Nitin Patil, Matthias Groß, Uwe Warnken, Thomas Longerich, Ashish Goyal, Maria Polycarpou-Schwarz, Michael Boutros, Peter Schirmacher, Anne Sophie Ernst, Sven Diederichs
Publikováno v:
Hepatology. 68:1817-1832
The identification of viability-associated long noncoding RNAs (lncRNAs) might be a promising rationale for new therapeutic approaches in liver cancer. Here, we applied an RNA interference screening approach in hepatocellular carcinoma (HCC) cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30b274afe2ef3b5fa2a7d795c6c9502c
https://doi.org/10.1002/hep.30102
https://doi.org/10.1002/hep.30102