Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Joëlle Wiels"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ovarian adenocarcinoma is the gynecological malignancy with the worst prognosis and the highest mortality rate. In the first stages of treatment, chemotherapy results effective, but its prolonged use and high doses lead to the appearance of resistanc
Externí odkaz:
https://doaj.org/article/fd3dda09b2594795a3404bdc5ccc8466
Autor:
Florian Daressy, Line Séguy, Loëtitia Favre, Sophie Corvaisier, Cécile Apel, Anne-Claire Groo, Marc Litaudon, Vincent Dumontet, Aurélie Malzert-Fréon, Sandy Desrat, Fanny Roussi, Aude Robert, Joëlle Wiels
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113546- (2022)
The overexpression of antiapoptotic members (BCL-2, BCL-xL, MCL-1, etc.) of the BCL-2 family contributes to tumor development and resistance to chemotherapy or radiotherapy. Synthetic inhibitors targeting these proteins have been developed, and some
Externí odkaz:
https://doaj.org/article/42554ec0867d47a2bab1e7e9b84fdb89
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2520-2532 (2020)
Post‐transplant lymphoproliferative disorders (PTLD) and Burkitt's lymphoma (BL) are B‐cell malignancies strongly associated with Epstein–Barr virus (EBV) infection. In these lymphoproliferative disorders, EBV infection induces an increase in t
Externí odkaz:
https://doaj.org/article/dadab8af23e74c8dac492bfa917f6383
Autor:
Aude Robert, Joëlle Wiels
Publikováno v:
Toxins, Vol 13, Iss 10, p 690 (2021)
Shiga toxins (Stxs), also known as Shiga-like toxins (SLT) or verotoxins (VT), constitute a family of structurally and functionally related cytotoxic proteins produced by the enteric pathogens Shigella dysenteriae type 1 and Stx-producing Escherichia
Externí odkaz:
https://doaj.org/article/22d19dd03fc145978ad666b95066e474
Publikováno v:
Toxins, Vol 12, Iss 5, p 316 (2020)
Shiga toxins (Stxs) expressed by the enterohaemorrhagic Escherichia coli and enteric Shigella dysenteriae 1 pathogens are protein synthesis inhibitors. Stxs have been shown to induce apoptosis via the activation of extrinsic and intrinsic pathways in
Externí odkaz:
https://doaj.org/article/9ccb4554a2824935a3508bb61cbfe04e
Autor:
Fatimata Bintou Sall, Anna Shmakova, Anna Karpukhina, Tatyana Tsfasman, Nikolai Lomov, Reynand Jay Canoy, David Boutboul, Eric Oksenhendler, Awa Oumar Toure, Marc Lipinski, Joëlle Wiels, Diego Germini, Yegor Vassetzky
Publikováno v:
Journal of Medical Virology. 95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fdd3da4ffe6f0d25b3af350772fbbf2
https://doi.org/10.1002/jmv.28633
https://doi.org/10.1002/jmv.28633
Autor:
Aude Robert, Joëlle Wiels, Line Séguy, Fanny Roussi, Aurélie Malzert-Fréon, Cécile Apel, Sandy Desrat, Vincent Dumontet, Vincent Guérineau, Jérôme Bignon, Florian Daressy, Marc Litaudon, Anne-Claire Groo, Florian Malard, Ewen Lescop
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (11), pp.1789-1798. ⟨10.1002/cmdc.202100011⟩
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (11), pp.1789-1798. ⟨10.1002/cmdc.202100011⟩
International audience; Drimane sesquiterpenoid dialdehydes are natural compounds with antiproliferative properties. Nevertheless, their mode of action has not yet been discovered. In this publication, we have demonstrated that various drimanes are p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe733da0567808247981502ebb8d293
https://doi.org/10.1002/cmdc.202100011
https://doi.org/10.1002/cmdc.202100011
Autor:
Joëlle Wiels, Éliane Viennot
Publikováno v:
Diogène. :9-27
Redige par deux feministes qui avaient vingt ans dans les annees 1970, dont l’une est devenue biologiste et l’autre specialiste des relations de pouvoir entre les sexes, cet article postule que l’humanite est en train de vivre un nouveau tourna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c2fa934fbf784768a73a1e1949db73
https://doi.org/10.3917/dio.267.0009
https://doi.org/10.3917/dio.267.0009
Autor:
Franck M. Andre, Yegor S. Vassetzky, Anna A. Shmakova, Diego Germini, Reynand Jay Canoy, Joëlle Wiels, Marc Lipinski
Publikováno v:
Gene Therapy
Gene Therapy, Nature Publishing Group, In press, ⟨10.1038/s41434-020-00194-x⟩
Gene Therapy, Nature Publishing Group, In press, ⟨10.1038/s41434-020-00194-x⟩
International audience; B-cell lines and primary PBMCs are notoriously hard to transfect, thus making genome editing, ectopic gene expression, or gene silencing experiments particularly tedious. Here we propose a novel efficient and reproducible prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e416a6d6563665c0187b20fe7e991a6
https://doi.org/10.1038/s41434-020-00194-x
https://doi.org/10.1038/s41434-020-00194-x
Autor:
Joëlle Wiels, Evelyne Peyre
Les discours scientifiques qui naissent au XVIIIe siecle sur la ‘nature des femmes’ et qui prennent une telle importance dans les siecles suivants, notamment au XIXe siecle en anthropologie et au XXe siecle en genetique sont, au moins en partie,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c520fa625c6e19c96bee9b78fe989884
http://journals.openedition.org/cedref/1642
http://journals.openedition.org/cedref/1642
