Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joël Tremblay-Marchand"'
Autor:
Yohan Bossé, Philippe Pibarot, Soumiya Amellah, Marie-Chloé Boulanger, Joël Tremblay Marchand, Rihab Bouchareb, Simon-Pierre Guay, Guada Mkannez, Mohamed Jalloul Nsaibia, Luigi Bouchard, Patrick Mathieu, Fayez Hadji, Sandra Guauque-Olarte, N. Gaudreault
Publikováno v:
Circulation. 134:1848-1862
Background: Calcific aortic valve disease is characterized by an abnormal mineralization of the aortic valve. Osteogenic activity in the aortic valve is under the control of NOTCH1 , which regulates the expression of key pro-osteogenic genes such as
Autor:
Patrick Mathieu, Simon C. Body, Jonathan G. Seidman, François Dagenais, Nathalie Gaudreault, Philippe Pibarot, Arnaud Droit, Yohan Bossé, Sandra Guauque-Olarte, Joël Tremblay-Marchand, Dimitris Kalavrouziotis
Publikováno v:
Physiological Genomics. 48:749-761
The molecular mechanisms leading to premature development of aortic valve stenosis (AS) in individuals with a bicuspid aortic valve are unknown. The objective of this study was to identify genes differentially expressed between calcified bicuspid aor
Autor:
Arnaud Droit, Patrick Mathieu, Jean-Claude Tardif, Yohan Bossé, Catherine Boileau, Marie-Pierre Dubé, Philippe Pibarot, Emilie Lavoie-Charland, David Messika-Zeitoun, B. Arsenault, Jonathan G. Seidman, Nathalie Gaudreault, Simon C. Body, Maxime Lamontagne, Joël Tremblay-Marchand, Sandra Guauque-Olarte
Publikováno v:
Circulation. Cardiovascular genetics. 8(6)
Background— Calcific aortic valve stenosis (AS) is a life-threatening disease with no medical therapy. The genetic architecture of AS remains elusive. This study combines genome-wide association studies, gene expression, and expression quantitative