Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joël T. van Mierlo"'
Autor:
Sander Witte, Léa V. Zinsli, Rafael Gonzalez-Serrano, Cassandra I. Matter, Martin J. Loessner, Joël T. van Mierlo, Matthew Dunne
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3416-3426 (2021)
Bacteriophages (phages) are widely used as biocontrol agents in food and as antibacterial agents for treatment of food production plant surfaces. An important feature of such phages is broad infectivity towards a given pathogenic species. Phages atta
Externí odkaz:
https://doaj.org/article/0d460deadad146a8976b394faba486b0
Autor:
Sander Witte, Linda Huijboom, Silvia Klamert, Leoni van de Straat, Steven Hagens, Lars Fieseler, Bert T. de Vegt, Joël T. van Mierlo
Shiga toxin producing Escherichia coli (STEC) are common etiological agents of food borne illnesses and outbreaks, most often caused by consuming contaminated beef products, followed by raw vegetables and dairy products. Patients infected with E. col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6da7bb201ec4bacb9b40aa392d442f
https://hdl.handle.net/11475/24457
https://hdl.handle.net/11475/24457
Autor:
Joël T van Mierlo, Gijs J Overheul, Benjamin Obadia, Koen W R van Cleef, Claire L Webster, Maria-Carla Saleh, Darren J Obbard, Ronald P van Rij
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004256 (2014)
The ongoing conflict between viruses and their hosts can drive the co-evolution between host immune genes and viral suppressors of immunity. It has been suggested that an evolutionary 'arms race' may occur between rapidly evolving components of the a
Externí odkaz:
https://doaj.org/article/838134ae2dbb41789dc7284e4b17adc4
Autor:
Léa V. Zinsli, Martin J. Loessner, Cassandra I. Matter, Rafael Gonzalez-Serrano, Joël T. van Mierlo, Sander Witte, Matthew Dunne
Publikováno v:
Computational and Structural Biotechnology Journal, 19
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3416-3426 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3416-3426 (2021)
Graphical abstract
Highlights • Receptor binding proteins (RBPs) are the primary determinants of phage host range. • Tail fiber of phage EP335 (gp13) recognizes E. coli serotypes O157 and O26. • Phage EP75 tailspikes are active towards E.
Highlights • Receptor binding proteins (RBPs) are the primary determinants of phage host range. • Tail fiber of phage EP335 (gp13) recognizes E. coli serotypes O157 and O26. • Phage EP75 tailspikes are active towards E.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6772e541cf8f0e85bd902a2d5d20fc30
Autor:
Joël T van Mierlo, Alfred W Bronkhorst, Gijs J Overheul, Sajna A Sadanandan, Jens-Ola Ekström, Marco Heestermans, Dan Hultmark, Christophe Antoniewski, Ronald P van Rij
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002872 (2012)
RNA interference (RNAi) is a major antiviral pathway that shapes evolution of RNA viruses. We show here that Nora virus, a natural Drosophila pathogen, is both a target and suppressor of RNAi. We detected viral small RNAs with a signature of Dicer-2
Externí odkaz:
https://doaj.org/article/3ae122e55e5e4e25b6ea0cc96229f328
Autor:
Steven Hagens, Sander Witte, Silvia Klamert, Lars Fieseler, Leoni van de Straat, Joël T. van Mierlo
Publikováno v:
Microbiology Resource Announcements
Phages vB_EcoM-EP75 (EP75) and vB_EcoP-EP335 (EP335) specifically infect Shiga toxin (Stx)-producing Escherichia coli (STEC) O157 strains. EP75 has a genome size of 158,143 bp and belongs to the genus Vi1virus.
Phages vB_EcoM-EP75 (EP75) and vB_
Phages vB_EcoM-EP75 (EP75) and vB_
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef147b0937126fde7a3a38edb16d0f07
https://hdl.handle.net/11475/18116
https://hdl.handle.net/11475/18116
Autor:
Pascal Miesen, Ronald P. van Rij, Koen W. R. van Cleef, Jelke J. Fros, Gorben P. Pijlman, Susan Schuster, Joël T. van Mierlo, Sandra Junglen, Marco Marklewitz, Gijs J. Overheul
Publikováno v:
Nucleic Acids Research, 42, 8732-44
Nucleic Acids Research, 42, 13, pp. 8732-44
Nucleic acids research, 42(13), 8732-8744
Nucleic Acids Research
Nucleic acids research 42 (2014) 13
Nucleic Acids Research, 42, 13, pp. 8732-44
Nucleic acids research, 42(13), 8732-8744
Nucleic Acids Research
Nucleic acids research 42 (2014) 13
Contains fulltext : 137475.pdf (Publisher’s version ) (Open Access) RNA interference (RNAi) is a crucial antiviral defense mechanism in insects, including the major mosquito species that transmit important human viruses. To counteract the potent an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c524c018d0e010d87c3d27dd27489383
https://doi.org/10.1093/nar/gku528
https://doi.org/10.1093/nar/gku528
Publikováno v:
Journal of Virology
Journal of Virology, 84, 8460-9
Journal of Virology, 84, 17, pp. 8460-9
Journal of Virology, 84, 8460-9
Journal of Virology, 84, 17, pp. 8460-9
The virion glycoproteins Gn and Gc of Bunyamwera virus (BUNV), the prototype of the Bunyaviridae family and also of the Orthobunyavirus genus, are encoded by the medium (M) RNA genome segment and are involved in both viral attachment and entry. After
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ba0864e8b416698c5ed6088e0cdadc
Autor:
Gijs J. Overheul, Joël T. van Mierlo, Daan Arends, Ronald P. van Rij, Christian Gilissen, Sarah H. Merkling
Publikováno v:
Scientific Reports, 5
Scientific Reports
Scientific Reports
Innate immunity is the first line of defence against pathogens and is essential for survival of the infected host. The fruit fly Drosophila melanogaster is an emerging model to study viral pathogenesis, yet antiviral defence responses remain poorly u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e741033d02c215836fbc324b72d9075
https://hdl.handle.net/2066/154187
https://hdl.handle.net/2066/154187
Autor:
Maria-Carla Saleh, Koen W. R. van Cleef, Gijs J. Overheul, Claire L. Webster, Benjamin Obadia, Joël T. van Mierlo, Darren J. Obbard, Ronald P. van Rij
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2014, 10 (7), pp.e1004256. ⟨10.1371/journal.ppat.1004256⟩
Plos Pathogens, 10, 7, pp. e1004256
PLoS Pathogens, Vol 10, Iss 7, p e1004256 (2014)
PLoS Pathogens, 2014, 10 (7), pp.e1004256. ⟨10.1371/journal.ppat.1004256⟩
van Mierlo, J T, Overheul, G J, Obadia, B, van Cleef, K W R, Webster, C L, Saleh, M C, Obbard, D J & van Rij, R P 2014, ' Novel Drosophila Viruses Encode Host-Specific Suppressors of RNAi ', PLoS Pathogens, vol. 10, no. 7, e1004256 . https://doi.org/10.1371/journal.ppat.1004256
Plos Pathogens, 10, e1004256
PLoS Pathogens, Public Library of Science, 2014, 10 (7), pp.e1004256. ⟨10.1371/journal.ppat.1004256⟩
Plos Pathogens, 10, 7, pp. e1004256
PLoS Pathogens, Vol 10, Iss 7, p e1004256 (2014)
PLoS Pathogens, 2014, 10 (7), pp.e1004256. ⟨10.1371/journal.ppat.1004256⟩
van Mierlo, J T, Overheul, G J, Obadia, B, van Cleef, K W R, Webster, C L, Saleh, M C, Obbard, D J & van Rij, R P 2014, ' Novel Drosophila Viruses Encode Host-Specific Suppressors of RNAi ', PLoS Pathogens, vol. 10, no. 7, e1004256 . https://doi.org/10.1371/journal.ppat.1004256
Plos Pathogens, 10, e1004256
The ongoing conflict between viruses and their hosts can drive the co-evolution between host immune genes and viral suppressors of immunity. It has been suggested that an evolutionary ‘arms race’ may occur between rapidly evolving components of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa204b49291801546c4cb78dcdae5d6
https://hal-pasteur.archives-ouvertes.fr/pasteur-01955495/file/10.1371%2Fjournal.ppat.1004256.PDF
https://hal-pasteur.archives-ouvertes.fr/pasteur-01955495/file/10.1371%2Fjournal.ppat.1004256.PDF