The insulin receptor is required for the development of the Drosophila peripheral nervous system.

Autor: Annie Dutriaux, Aurélie Godart, Anna Brachet, Joël Silber

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e71857 (2013)

The Insulin Receptor (InR) in Drosophila presents features conserved in its mammalian counterparts. InR is required for growth; it is expressed in the central and embryonic nervous system and modulates the time of differentiation of the eye photorece

Externí odkaz: https://doaj.org/article/b09a34a638ac4f5d9a38b66672921b27

The Drosophila wing differentiation factor Vestigial–Scalloped is required for cell proliferation and cell survival at the dorso-ventral boundary of the wing imaginal disc

Autor: Domenico Flagiello, J. L. Becker, Rénald Delanoue, Kevin Legent, Joël Silber, P. Vaudin, N Godefroy, Annie Dutriaux

Publikováno v: Cell Death & Differentiation. 11:110-122

Links between genes involved in development, proliferation and apoptosis have been difficult to establish. In the Drosophila wing disc, the vestigial (vg) and the scalloped (sd) gene products dimerize to form a functional transcription factor. Ectopi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da412453a0eb0709ecbdb95c580b6b31
https://doi.org/10.1038/sj.cdd.4401321

Mef2 Interacts with the Notch Pathway during Adult Muscle Development in Drosophila melanogaster

Autor: Petar Kasherov, Charlotte Caine, Joël Silber, Alexis Lalouette

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (9), pp.e108149. ⟨10.1371/journal.pone.0108149⟩
PLoS ONE, Vol 9, Iss 9, p e108149 (2014)

Myogenesis of indirect flight muscles (IFMs) in Drosophila melanogaster follows a well-defined cellular developmental scheme. During embryogenesis, a set of cells, the Adult Muscle Precursors (AMPs), are specified. These cells will become proliferati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41421d4f6ef8f262dffadc0c0dfcec43
https://hal.archives-ouvertes.fr/hal-01130318

Suppressors of the vestigial mutant phenotype increase the level of expression of the gene

Autor: Joël Silber, Christian Cibert, Sandro Cavicchi, Alain Zider, Domenico Flagiello, Nadia Fellini

Publikováno v: Development, Growth and Differentiation. 38:557-564

Suppressor genes of the vestigial phenotype have been isolated in a wild-type population. These suppressors have an effect on different wing mutants and are allele-specific in the case of vestigial. In a vgBG background they produced overgrowth of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::257a645d46fa42acd364703b34577b1a
https://doi.org/10.1046/j.1440-169x.1996.t01-4-00012.x

Alteration of TEAD1 expression levels confers apoptotic resistance through the transcriptional up-regulation of Livin

Autor: Kevin Legent, André Landin Malt, Alain Zider, Julie Cagliero, Joël Silber, Domenico Flagiello

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45498 (2012)
PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (9), pp.e45498. ⟨10.1371/journal.pone.0045498⟩

International audience; BACKGROUND: TEA domain (TEAD) proteins are highly conserved transcription factors involved in embryonic development and differentiation of various tissues. More recently, emerging evidences for a contribution of these proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee14a9105cc628dd24401001520ccf7
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029054/?tool=EBI