Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Joël Lachuer"'
Autor:
Anne-Laure Hemonnot-Girard, Cédric Meersseman, Manuela Pastore, Valentin Garcia, Nathalie Linck, Catherine Rey, Amine Chebbi, Freddy Jeanneteau, Stephen D. Ginsberg, Joël Lachuer, Christelle Reynes, François Rassendren, Hélène Hirbec
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-26 (2022)
Abstract Background Research in recent years firmly established that microglial cells play an important role in the pathogenesis of Alzheimer's disease (AD). In parallel, a series of studies showed that, under both homeostatic and pathological condit
Externí odkaz:
https://doaj.org/article/9574a05f72834460ae566069892f4b65
Autor:
Aurélie Bellanger, Diep T. Le, Julie Vendrell, Anne Wierinckx, Lőrinc S. Pongor, Jérôme Solassol, Joël Lachuer, Philippe Clezardin, Balázs Győrffy, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Oncogene alternative splicing events can create distinct functional transcripts that offer new candidate prognostic biomarkers for breast cancer. ZNF217 is a well-established oncogene but its exon 4-skipping isoform (ZNF217-ΔE4) has never been inves
Externí odkaz:
https://doaj.org/article/447ddc6507a346b49865519fc7d3eb12
Autor:
Julien Fouret, Frédéric G. Brunet, Martin Binet, Noémie Aurine, Francois Enchéry, Séverine Croze, Marie Guinier, Abdelghafar Goumaidi, Doris Preininger, Jean-Nicolas Volff, Marc Bailly-Bechet, Joël Lachuer, Branka Horvat, Catherine Legras-Lachuer
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Indian fruit bats, flying fox Pteropus medius was identified as an asymptomatic natural host of recently emerged Nipah virus, which is known to induce a severe infectious disease in humans. The absence of P. medius genome sequence presents an importa
Externí odkaz:
https://doaj.org/article/0b5640989cbc46aa8ff154c268c7e7a0
Autor:
Caterina F. Donini, Myriam El Helou, Anne Wierinckx, Balázs Győrffy, Sophie Aires, Aurélie Escande, Séverine Croze, Philippe Clezardin, Joël Lachuer, Mona Diab-Assaf, Sandra E. Ghayad, Béatrice Fervers, Vincent Cavaillès, Véronique Maguer-Satta, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
It is of utmost importance to decipher the role of chronic exposure to low doses of environmental carcinogens on breast cancer progression. The early-transformed triple-negative human mammary MCF10AT1 cells were chronically (60 days) exposed to low d
Externí odkaz:
https://doaj.org/article/9deef468b8a74ab58e8ea72c1647ba1c
Autor:
Anne Wierinckx, Etienne Delgrange, Philippe Bertolino, Patrick François, Philippe Chanson, Emmanuel Jouanneau, Joël Lachuer, Jacqueline Trouillas, Gérald Raverot
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Sex-related differences have been reported in various cancers, in particular men with lactotroph tumors have a worse prognosis than women. While the underlying mechanism of this sexual dimorphism remains unclear, it has been suggested that a lower es
Externí odkaz:
https://doaj.org/article/718ba2bd85d14e10847af69d01b2d8f3
Autor:
Olivia Gay, Benoît Gilquin, Nicole Assard, Pascal Stuelsatz, Christian Delphin, Joël Lachuer, Xavier Gidrol, Jacques Baudier
Publikováno v:
Biology Open, Vol 5, Iss 10, Pp 1351-1361 (2016)
Refilins (RefilinA and RefilinB) are members of a novel family of Filamin binding proteins that function as molecular switches to conformationally alter the Actin filament network into bundles. We show here that Refilins are extremely labile proteins
Externí odkaz:
https://doaj.org/article/863c12762cb64e8f992e3b15fb99c7d1
Autor:
Elise Berthel, Anne Vincent, Lauriane Eberst, Adrian Gabriel Torres, Estelle Dacheux, Catherine Rey, Virginie Marcel, Hermes Paraqindes, Joël Lachuer, Frédéric Catez, Lluis Ribas de Pouplana, Isabelle Treilleux, Jean-Jacques Diaz, Nicole Dalla Venezia
Publikováno v:
Cells, Vol 9, Iss 4, p 941 (2020)
BRCA1 inactivation is a hallmark of familial breast cancer, often associated with aggressive triple negative breast cancers. BRCA1 is a tumor suppressor with known functions in DNA repair, transcription regulation, cell cycle control, and apoptosis.
Externí odkaz:
https://doaj.org/article/1995e12a4e63473fab4ea3f29eaded18
Autor:
Baptiste Gras, Laurent Jacqueroud, Anne Wierinckx, Christelle Lamblot, Frédérique Fauvet, Joël Lachuer, Alain Puisieux, Stéphane Ansieau
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92254 (2014)
By fostering cell commitment to the epithelial-to-mesenchymal transition (EMT), SNAIL proteins endow cells with motility, thereby favoring the metastatic spread of tumor cells. Whether the phenotypic change additionally facilitates tumor initiation h
Externí odkaz:
https://doaj.org/article/1632780bb24d49aaacefdffef0c2f107
Autor:
Estelle Dacheux, Anne Vincent, Nicolas Nazaret, Christophe Combet, Anne Wierinckx, Sylvie Mazoyer, Jean-Jacques Diaz, Joël Lachuer, Nicole Dalla Venezia
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67313 (2013)
BRCA1 (Breast Cancer 1) has been implicated in a number of cellular processes, including transcription regulation, DNA damage repair and protein ubiquitination. We previously demonstrated that BRCA1 interacts with PABP1 (Poly(A)-Binding Protein 1) an
Externí odkaz:
https://doaj.org/article/dcc2bb5e219f423e9378db88e2347a89
Autor:
Anne-Pierre Morel, George W Hinkal, Clémence Thomas, Frédérique Fauvet, Stéphanie Courtois-Cox, Anne Wierinckx, Mojgan Devouassoux-Shisheboran, Isabelle Treilleux, Agnès Tissier, Baptiste Gras, Julie Pourchet, Isabelle Puisieux, Gareth J Browne, Douglas B Spicer, Joël Lachuer, Stéphane Ansieau, Alain Puisieux
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002723 (2012)
The epithelial-mesenchymal transition (EMT) is an embryonic transdifferentiation process consisting of conversion of polarized epithelial cells to motile mesenchymal ones. EMT-inducing transcription factors are aberrantly expressed in multiple tumor
Externí odkaz:
https://doaj.org/article/cea742889eda4b7e8c8e6148940ce073