Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Joël Acker"'
Autor:
Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Beatrice Capuzzi, Noé Palmic, Christine Conesa, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Cryo-EM structures of Ty1 integrase-Pol III complexes reveal determinants of Ty1 targeting upstream of Pol III-transcribed genes, and a functional impact of the integrase on Pol III activity that may increase the probability of Ty1 integration.
Externí odkaz:
https://doaj.org/article/ae5e1040373b42eb93f7571525af5479
Autor:
Anastasia Barkova, Indranil Adhya, Christine Conesa, Amna Asif-Laidin, Amandine Bonnet, Elise Rabut, Carine Chagneau, Pascale Lesage, Joël Acker
Publikováno v:
Mobile DNA, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Transposable elements are ubiquitous and play a fundamental role in shaping genomes during evolution. Since excessive transposition can be mutagenic, mechanisms exist in the cells to keep these mobile elements under control. Altho
Externí odkaz:
https://doaj.org/article/53111f1a5c5f48a194b3d5c26d9dc0a2
Autor:
Joël Acker, Ngoc-Thuy-Trinh Nguyen, Marie Vandamme, Arounie Tavenet, Audrey Briand-Suleau, Christine Conesa
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114587 (2014)
Sub1 and Maf1 exert an opposite effect on RNA polymerase III transcription interfering with different steps of the transcription cycle. In this study, we present evidence that Sub1 and Maf1 also exhibit an opposite role on yeast chronological life sp
Externí odkaz:
https://doaj.org/article/71fe30799e2c44e496351eefab49a89d
Autor:
Marina C. Nocente, Anida Mesihovic Karamitsos, Emilie Drouineau, Waad Albawardi, Cécile Dulary, Florence Ribierre, Hélène Picaud, Olivier Alibert, Joël Acker, Jean-Christophe Aude, Nick Gilbert, Françoise Ochsenbein, Sophie Chantalat, Matthieu Gérard
BRG1, the catalytic subunit of the mammalian SWI/SNF complexes, is essential for chromatin opening at enhancers. However, the nature of the open chromatin remains unclear. Here we show that in addition to producing histone-free DNA, BRG1 generates he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5563f1d687d0597593393ff6cecfcc34
https://doi.org/10.1101/2022.09.15.507958
https://doi.org/10.1101/2022.09.15.507958
Autor:
Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Noé Palmic, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero
SummaryThe yeast Ty1 retrotransposon integrates upstream of genes transcribed by RNA polymerase III (Pol III). Specificity of integration is mediated by an interaction between the Ty1 integrase (IN1) and Pol III, currently uncharacterized at the atom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7497fda6a62427370447da274cd2e646
https://doi.org/10.1101/2022.03.07.483246
https://doi.org/10.1101/2022.03.07.483246
Autor:
Noé Palmic, Joël Acker, Pascale Lesage, Christine Conesa, Rachid Menouni, Amandine Bonnet, Hélène Fayol, Camille Grison, Amna Asif-Laidin, Indranil Adhya
SUMMARYIntegration of transposable elements into the genome is mutagenic. Mechanisms that target integration into relatively safe locations and minimize deleterious consequences for cell fitness have emerged during evolution. In budding yeast, the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84d2596ca0c3f9c58894f500e0368c6
https://doi.org/10.1101/2019.12.18.879569
https://doi.org/10.1101/2019.12.18.879569
Publikováno v:
Gene
Gene, Elsevier, 2015, 556 (1), pp.51-60. 〈10.1016/j.gene.2014.07.070〉
Gene, Elsevier, 2015, 556 (1), pp.51-60. ⟨10.1016/j.gene.2014.07.070⟩
Gene, 2015, 556 (1), pp.51-60. ⟨10.1016/j.gene.2014.07.070⟩
Gene, Elsevier, 2015, 556 (1), pp.51-60. 〈10.1016/j.gene.2014.07.070〉
Gene, Elsevier, 2015, 556 (1), pp.51-60. ⟨10.1016/j.gene.2014.07.070⟩
Gene, 2015, 556 (1), pp.51-60. ⟨10.1016/j.gene.2014.07.070⟩
International audience; To identify the proteins associated with the RNA polymerase III (Pol III) machinery in exponentially growing yeast cells, we developed our own tandem chromatin affinity purification procedure (TChAP) after in vivo cross-link,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc54008c276e12cf80883ffbec789098
https://hal.archives-ouvertes.fr/hal-01444873
https://hal.archives-ouvertes.fr/hal-01444873
Autor:
Christoph W. Müller, Carlos Fernández-Tornero, Pierre Legrand, Anastasia Mylona, Melina Haupt, Joël Acker, André Sentenac
Publikováno v:
Molecular Cell. 24(2):221-232
Yeast RNA polymerase III is recruited upon binding of subcomplexes tauA and tauB of transcription factor IIIC (TFIIIC) to the A and B blocks of tRNA gene promoters. The tauB subcomplex consists of subunits tau60, tau91, and tau138. We determined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc78f56d0319636ee7bad3e832f4887f
Autor:
Vladimir Khazak, Claude Kedinger, Michael de Graaff, Marc Vigneron, Joël Acker, Isabelle Cheynel
Publikováno v:
Journal of Biological Chemistry. 272:16815-16821
As an initial approach to characterizing the molecular structure of the human RNA polymerase II (hRPB), we systematically investigated the protein-protein contacts that the subunits of this enzyme may establish with each other. To this end, we applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db793c7f44503de4e2304ea92bf47a7
https://doi.org/10.1074/jbc.272.27.16815
https://doi.org/10.1074/jbc.272.27.16815
Publikováno v:
Biochimica et biophysica acta. 1829(3-4)
Recent data indicate that the well-defined transcription machinery of RNA polymerase III (Pol III) is probably more complex than commonly thought. In this review, we describe the yeast basal transcription factors of Pol III and their involvements in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd63d00357a5738dbb7d110b5a3d56c
https://pubmed.ncbi.nlm.nih.gov/23063749
https://pubmed.ncbi.nlm.nih.gov/23063749