Zobrazeno 1 - 4
of 4
pro vyhledávání: '"João von Gilsa Lopes"'
Autor:
Maria Arez, Melanie Eckersley-Maslin, Tajda Klobučar, João von Gilsa Lopes, Felix Krueger, Annalisa Mupo, Ana Cláudia Raposo, David Oxley, Samantha Mancino, Anne-Valerie Gendrel, Bruno Bernardes de Jesus, Simão Teixeira da Rocha
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is associated with epigenetic alterations. Here the authors assess DNA methylation in detail in multiple female and male mouse iPSC lines generated with different protocols and fin
Externí odkaz:
https://doaj.org/article/fb75e50bfe994000b134b58a729bd94e
Autor:
José Manuel Inácio, João von Gilsa Lopes, Ana Mafalda Silva, Fernando Cristo, Sara Marques, Matthias E. Futschik, José António Belo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Deciphering the clues of a regenerative mechanism for the mammalian adult heart would save millions of lives in the near future. Heart failure due to cardiomyocyte loss is still one of the significant health burdens worldwide. Here, we show the poten
Externí odkaz:
https://doaj.org/article/7c772696ca05426eb4679fab335eeca1
Publikováno v:
Current Stem Cell Research & Therapy. 18
Background: Dand5 encodes a protein that acts as an antagonist to Nodal/TGF-β and Wnt pathways. A mouse knockout (KO) model has shown that this molecule is associated with left-right asymmetry and cardiac development, with its depletion causing hete
Autor:
José António Belo, Matthias E. Futschik, João von Gilsa Lopes, Fernando Cristo, Ana Mafalda Silva, Sara Marques, José M. Inácio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Cell and Developmental Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Funding: This work was supported by the Fundação para a Ciência e a Tecnologia (PTDC/BIM-MED/3363/2014) and Scientific Employment Stimulus to JI (Norma Transitória 8189/2018), predoctoral fellowship to JG (FCT; PD/BD/136919/2018) and postdoctoral