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pro vyhledávání: '"João de Proença"'
Autor:
Pedro Guedes-Dias, Brígida R. Pinho, Tânia R. Soares, João de Proença, Michael R. Duchen, Jorge M.A. Oliveira
Publikováno v:
Neurobiology of Disease, Vol 90, Iss , Pp 51-57 (2016)
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by polyglutamine expansion mutations in the huntingtin protein. Despite its ubiquitous distribution, expression of mutant huntingtin (mHtt) is particularly detrimental to med
Externí odkaz:
https://doaj.org/article/ab13d0a22963488ca1ff9ff1f22c587f
Autor:
Michael R. Duchen, Brígida R. Pinho, Tânia Soares, Pedro Guedes-Dias, João de Proença, Jorge M.A. Oliveira
Publikováno v:
Neurobiology of Disease, Vol 90, Iss, Pp 51-57 (2016)
Neurobiology of Disease
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Neurobiology of Disease
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by polyglutamine expansion mutations in the huntingtin protein. Despite its ubiquitous distribution, expression of mutant huntingtin (mHtt) is particularly detrimental to med
Autor:
Tânia Soares, Brígida R. Pinho, Pedro Guedes-Dias, Jorge M.A. Oliveira, João de Proença, Ana Leitão-Rocha, Michael R. Duchen
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Striatal neurons are vulnerable to Huntington's disease (HD). Decreased levels of acetylated alpha-tubulin and impaired mitochondrial dynamics, such as reduced motility and excessive fission, are associated with HD; however, it remains unclear whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a867cdc9de170bc56bac6898754667
https://repositorio-aberto.up.pt/handle/10216/104700
https://repositorio-aberto.up.pt/handle/10216/104700