Zobrazeno 1 - 10
of 14
pro vyhledávání: '"João Victor Cabral-Costa"'
Publikováno v:
Essays in Biochemistry. 67:63-75
Astrocytes are a heterogenous population of macroglial cells spread throughout the central nervous system with diverse functions, expression signatures, and intricate morphologies. Their subcellular compartments contain a distinct range of mitochondr
Autor:
Vitor de Miranda Ramos, Julian D.C. Serna, Eloisa A. Vilas-Boas, João Victor Cabral-Costa, Fernanda M. da Cunha, Tetsushi Kataura, Viktor I. Korolchuk, Alicia J. Kowaltowski
In addition to their central role in energy metabolism, mitochondria can shape intracellular calcium (Ca2+) signaling through the concerted activity of Ca2+uptake to the matrix through the mitochondrial calcium uniporter, and efflux from the matrix m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b36e977133a58ae689d6b9ecee096d4
https://doi.org/10.1101/2023.03.17.533187
https://doi.org/10.1101/2023.03.17.533187
Autor:
João Victor Cabral‐Costa, Carlos Vicente‐Gutiérrez, Jesús Agulla, Rebeca Lapresa, John W. Elrod, Ángeles Almeida, Juan P. Bolaños, Alicia J. Kowaltowski
Intracellular Ca2+ concentrations are strictly controlled by plasma membrane transporters, the endoplasmic reticulum, and mitochondria, in which Ca2+ uptake is mediated by the mitochondrial calcium uniporter complex (MCUc), while efflux occurs mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e992b8985307c463f8da0020f849f53
https://doi.org/10.1101/2022.09.16.507284
https://doi.org/10.1101/2022.09.16.507284
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Microglial activation involves both fragmentation of the mitochondrial network and changes in cellular Ca2+ homeostasis, but possible modifications in mitochondrial calcium uptake have never been described in this context. Here we report that activat
Autor:
Vitor Miranda Ramos, João Victor Cabral‐Costa, Julian D. Serna, Fernanda M. Cunha, Alicia J. Kowaltowski
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Autor:
Eloisa A. Vilas-Boas, João Victor Cabral-Costa, Vitor M. Ramos, Camille C. Caldeira da Silva, Alicia J. Kowaltowski
Calcium (Ca2+) is a key regulator in diverse intracellular signaling pathways, and has long been implicated in metabolic control and mitochondrial function. Mitochondria can actively take up large amounts of Ca2+, thereby acting as important intracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0498b8e88b6bffff71e8b8294085083
https://doi.org/10.1101/2022.04.12.488015
https://doi.org/10.1101/2022.04.12.488015
Autor:
Eloisa A. Vilas-Boas, João Victor Cabral-Costa, Vitor M. Ramos, Camille C. Caldeira da Silva, Alicia J. Kowaltowski
Publikováno v:
Journal of Biological Chemistry. 299:102904
Autor:
Alexandre Bruni-Cardoso, João Victor Cabral-Costa, Alicia J. Kowaltowski, Isabela G. Gonçalves, Sergio L. Menezes-Filho, Orian S. Shirihai, Phablo Abreu, Nathanael Miller, Francisco R.M. Laurindo, Essam A. Assali, Patricia Nolasco
Publikováno v:
FASEB J
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Changes in mitochondrial size and shape have been implicated in several physiologic processes, but their role in mitochondrial Ca(2+) uptake regulation and overall cellular Ca(2+) homeostasis is largely unknown. Here we show that modulating mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e6aa0c7ba81c5dfdcca66b6a515766
https://europepmc.org/articles/PMC9272750/
https://europepmc.org/articles/PMC9272750/
Autor:
Caio Henrique Mazucanti, Cristoforo Scavone, Elisa Mitiko Kawamoto, Andrea Rodrigues Vasconcelos, João Victor Cabral-Costa
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Frontiers in Endocrinology
Frontiers in Endocrinology
Steroid hormones, such as sex hormones and glucocorticoids, have been demonstrated to play a role in different cellular processes in the central nervous system, ranging from neurodevelopment to neurodegeneration. Environmental factors, such as calori