Zobrazeno 1 - 2
of 2
pro vyhledávání: '"João V. S. Ormonde"'
Publikováno v:
The Journal of Immunology. 201:3431-3442
Activation of LCK is required for canonical TCR signaling leading to T cell responses. LCK activation also initiates a negative feedback loop mediated by the phosphatase SHP-1 that turns off TCR signaling. In this article, we report that the thousand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5815aece9e9b6c4a2bf24e92ea28396f
https://doi.org/10.4049/jimmunol.1800284
https://doi.org/10.4049/jimmunol.1800284
Publikováno v:
Critical reviews in immunology. 39(1)
Signaling from the T cell receptor for antigen turns on the physiological response of a T cell. The canonical TCR signaling pathway relies on early activation of the Src kinase LCK. This step initiates a cascade of events that lead not only to the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65283ed5a957d8b875fca641d124f93e
https://pubmed.ncbi.nlm.nih.gov/31679194
https://pubmed.ncbi.nlm.nih.gov/31679194