Zobrazeno 1 - 10
of 31
pro vyhledávání: '"João Santana, Silva"'
Autor:
Gabriel Martins da Costa Manso, Jefferson Elias-Oliveira, Jhefferson Barbosa Guimarães, Ítalo Sousa Pereira, Vanessa Fernandes Rodrigues, Beatriz Burger, Daianne Maciely Carvalho Fantacini, Lucas Eduardo Botelho de Souza, Hosana Gomes Rodrigues, Vânia Luiza Deperon Bonato, João Santana Silva, Simone Gusmão Ramos, Rita Cassia Tostes, Adriana Oliveira Manfiolli, Carolina Caliari-Oliveira, Daniela Carlos
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 79-89 (2023)
Introduction: Diabetes mellitus (DM) is a chronic disease and a major cause of mortality and morbidity worldwide. The hyperglycemia caused by DM induces micro and macrovascular complications that lead, among other consequences, to chronic wounds and
Externí odkaz:
https://doaj.org/article/700353414ef94be48c935aab97244cd0
Autor:
Jefferson Antônio Leite, Luísa Menezes, Eloisa Martins, Tamara Silva Rodrigues, Lucas Tavares, Anna Ebering, Carsten Schelmbauer, Guilherme C. Martelossi Cebinelli, Valeriya Zinina, Artemiy Golden, Natalia Soshnikova, Dario S. Zamboni, Fernando Q. Cunha, Magdalena Huber, João Santana Silva, Ari Waisman, Daniela Carlos, Niels Olsen Saraiva Câmara
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108134- (2023)
Summary: AIM2 is an interferon-inducible HIN-200 protein family member and is well-documented for its roles in innate immune responses as a DNA sensor. Recent studies have highlighted AIM2’s function on regulatory T cells (Treg) and follicular T ce
Externí odkaz:
https://doaj.org/article/4aa4b8055f9049c997033944049dce04
Autor:
Victória Riquena Grosche, Leandro Peixoto Ferreira Souza, Giulia Magalhães Ferreira, Marco Guevara-Vega, Tamara Carvalho, Romério Rodrigues dos Santos Silva, Karla Lilian Rodrigues Batista, Rodrigo Paolo Flores Abuna, João Santana Silva, Marília de Freitas Calmon, Paula Rahal, Luis Cláudio Nascimento da Silva, Bruno Silva Andrade, Claudener Souza Teixeira, Robinson Sabino-Silva, Ana Carolina Gomes Jardim
Publikováno v:
Viruses, Vol 15, Iss 9, p 1886 (2023)
The SARS-CoV-2 entry into host cells is mainly mediated by the interactions between the viral spike protein (S) and the ACE-2 cell receptor, which are highly glycosylated. Therefore, carbohydrate binding agents may represent potential candidates to a
Externí odkaz:
https://doaj.org/article/7f5f2b316d6445ae81ac177c591ee4ab
Autor:
Mauro César Cafundó Morais, Diogo Silva, Matheus Marques Milagre, Maykon Tavares de Oliveira, Thaís Pereira, João Santana Silva, Luciano da F. Costa, Paola Minoprio, Roberto Marcondes Cesar Junior, Ricardo Gazzinelli, Marta de Lana, Helder I. Nakaya
Publikováno v:
PeerJ, Vol 10, p e13470 (2022)
Chagas disease is a life-threatening illness caused by the parasite Trypanosoma cruzi. The diagnosis of the acute form of the disease is performed by trained microscopists who detect parasites in blood smear samples. Since this method requires a dedi
Externí odkaz:
https://doaj.org/article/c66620227a184bd388f79ed1a0db3675
Autor:
Karine Garcez Schuster Franco, Fabio Jorge Ramalho de Amorim, Mário Adriano Santos, Carla Virgínia Vieira Rollemberg, Fabricia Alvisi de Oliveira, Alex Vianey Callado França, Camilla Natália Oliveira Santos, Lucas Sousa Magalhães, Rodrigo Anselmo Cazzaniga, Frederico Santana de Lima, Luciana Benevides, Vanessa Carregaro, João Santana Silva, Hugo Leite de Farias Brito, Daniel Alvarenga Fernandes, Ângela Maria da Silva, Roque Pacheco de Almeida, Márcio Bezerra-Santos, Amélia Ribeiro de Jesus
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
This is a case series study to evaluate immunological markers associated with schistosomiasis advanced fibrosis, including 69 patients from an endemic area from the State of Sergipe and from the Hepatology Service of the University Hospital in Sergip
Externí odkaz:
https://doaj.org/article/bb4a540e61bb4479ae71beae6e07a258
Autor:
Débora Maria Soares de Souza, Maria Cláudia Silva, Silvia Elvira Barros Farias, Ana Paula de J. Menezes, Cristiane Maria Milanezi, Karine de P. Lúcio, Nívia Carolina N. Paiva, Paula Melo de Abreu, Daniela Caldeira Costa, Kelerson Mauro de Castro Pinto, Guilherme de Paula Costa, João Santana Silva, André Talvani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background:Trypanosoma cruzi is a protozoan parasite that causes Chagas disease and affects 6–7 million people mainly in Latin America and worldwide. Here, we investigated the effects of hyperlipidic diets, mainly composed of olive oil or lard on e
Externí odkaz:
https://doaj.org/article/17e4f68814f84153aa87eaca58ef376e
Autor:
Jefferson Elias-Oliveira, Jefferson Antônio Leite, Ítalo Sousa Pereira, Jhefferson Barbosa Guimarães, Gabriel Martins da Costa Manso, João Santana Silva, Rita Cássia Tostes, Daniela Carlos
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The intestinal microbiome maintains a close relationship with the host immunity. This connection fosters a health state by direct and indirect mechanisms. Direct influences occur mainly through the production of short-chain fatty acids (SCFAs), gastr
Externí odkaz:
https://doaj.org/article/52497327772146509fbfc0d9641ee7cd
Autor:
Natália Ketelut-Carneiro, Camila Oliveira Silva Souza, Luciana Benevides, Luiz Gustavo Gardinassi, Maria Cláudia Silva, Lucas Alves Tavares, Dario Simões Zamboni, João Santana Silva
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007990 (2019)
The granulomatous lesion resulting from infection with the fungus Paracoccidioides brasiliensis is characterized by a compact aggregate of mature cells, surrounded by a fibroblast- and collagen-rich content. Granuloma formation requires signaling eli
Externí odkaz:
https://doaj.org/article/f4ce1a43c59741c299e701c5c9ae0fa2
Autor:
Jefferson Antônio Leite, Gabriela Pessenda, Isabel C. Guerra-Gomes, Alynne Karen Mendonça de Santana, Camila André Pereira, Frederico Ribeiro Campos Costa, Simone G. Ramos, Dario Simões Zamboni, Ana Maria Caetano Faria, Danilo Candido de Almeida, Niels Olsen Saraiva Câmara, Rita C. Tostes, João Santana Silva, Daniela Carlos
Publikováno v:
Cells, Vol 9, Iss 4, p 959 (2020)
Pattern recognition receptors (PRRs), such as Nod2, Nlrp3, Tlr2, Trl4, and Tlr9, are directly involved in type 1 diabetes (T1D) susceptibility. However, the role of the cytosolic DNA sensor, AIM2, in T1D pathogenesis is still unknown. Here, we demons
Externí odkaz:
https://doaj.org/article/bad6db771ce5412c9a4350cced9eed0b
Autor:
Maria Cláudia Silva, Carlos Alessandro Fuzo, Isadora Marques Paiva, Naira Lopes Bibó, Maykon Tavares de Oliveira, Hellen Anastácia da Silva Soares, Christophe Chevillard, Jorge Kalil, Edecio Cunha-Neto, Thiago Mattar Cunha, João Santana Silva
Publikováno v:
Immunobiology
Immunobiology, 2022, 227 (5), pp.152242. ⟨10.1016/j.imbio.2022.152242⟩
Immunobiology, 2022, 227 (5), pp.152242. ⟨10.1016/j.imbio.2022.152242⟩
International audience; Single nucleotide polymorphisms (SNPs) that do not change the composition of amino acids and cause synonymous mutations (sSNPs) were previously considered to lack any functional roles. However, sSNPs have recently been shown t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6198659dc19668f63ed861e81153fc54
https://hal.science/hal-03934958/document
https://hal.science/hal-03934958/document
