Zobrazeno 1 - 10
of 44
pro vyhledávání: '"João S. Soares"'
Autor:
Hao Liu, João S. Soares, John Walmsley, David S. Li, Samarth Raut, Reza Avazmohammadi, Paul Iaizzo, Mark Palmer, Joseph H. Gorman, Robert C. Gorman, Michael S. Sacks
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Myocardial infarction (MI) rapidly impairs cardiac contractile function and instigates maladaptive remodeling leading to heart failure. Patient-specific models are a maturing technology for developing and determining therapeutic modalities f
Externí odkaz:
https://doaj.org/article/82d45691d36245a6ae9cd5b612ac0300
Autor:
Paul A. Iaizzo, Mark Palmer, John Walmsley, Robert C. Gorman, Samarth S. Raut, João S. Soares, Michael S. Sacks, David Li, Hao Liu, Reza Avazmohammadi, Joseph H. Gorman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Myocardial infarction (MI) rapidly impairs cardiac contractile function and instigates maladaptive remodeling leading to heart failure. Patient-specific models are a maturing technology for developing and determining therapeutic modalities for MI tha
Publikováno v:
Functional Imaging and Modeling of the Heart ISBN: 9783030787097
FIMH
FIMH
Perivascular support and tethering are likely relevant factors in vascular mechanics and one of the possible causes of deformational heterogeneity of the aortic wall. Besides these effects, the thoracic aorta interacts with the heart and other moving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aab06b6dfeff61d1f87782b4ed58e32
https://doi.org/10.1007/978-3-030-78710-3_31
https://doi.org/10.1007/978-3-030-78710-3_31
Publikováno v:
Journal of Biomechanical Engineering. 142
The establishment of in vivo, noninvasive patient-specific, and regionally resolved techniques to quantify aortic properties is key to improving clinical risk assessment and scientific understanding of vascular growth and remodeling. A promising and
Publikováno v:
Acta Biomaterialia. 51:220-236
Formation of engineering tissues (ET) remains an important scientific area of investigation for both clinical translational and mechanobiological studies. Needled-nonwoven (NNW) scaffolds represent one of the most ubiquitous biomaterials based on the
Autor:
Reza Avazmohammadi, Samarth S. Raut, David Li, João S. Soares, Robert C. Gorman, Michael S. Sacks
Publikováno v:
Annual review of biomedical engineering. 21
Understanding and predicting the mechanical behavior of myocardium under healthy and pathophysiological conditions are vital to developing novel cardiac therapies and promoting personalized interventions. Within the past 30 years, various constitutiv
Autor:
Michael S. Sacks, Ankush Aggarwal, Will Zhang, David Kamensky, João S. Soares, Kristen R. Feaver
Publikováno v:
Cardiovascular Engineering and Technology. 7:309-351
The use of replacement heart valves continues to grow due to the increased prevalence of valvular heart disease resulting from an ageing population. Since bioprosthetic heart valves (BHVs) continue to be the preferred replacement valve, there continu
Autor:
Robert C. Gorman, Michael S. Sacks, Reza Avazmohammadi, David Li, João S. Soares, James J. Pilla, Thomas J. Eperjesi
Publikováno v:
J Biomech
Although studied for many years, there remain continued gaps in our fundamental understanding of cardiac kinematics, such as the nature and extent of heart wall volumetric changes that occur over the cardiac cycle. Such knowledge is especially import
Autor:
Edward W. Hsu, Samer S. Merchant, Emilio A. Mendiola, Michael S. Sacks, David Li, Zhiqiang Chen, Reza Avazmohammadi, Richard A. F. Dixon, João S. Soares, Peter Vanderslice
Pulmonary arterial hypertension (PAH) imposes pressure overload on the right ventricle (RV), leading to RV enlargement via the growth of cardiac myocytes and remodeling of the collagen fiber architecture. The effects of these alterations on the funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f731fd6df1cbe647c89528bb60f9f2e
https://europepmc.org/articles/PMC6318016/
https://europepmc.org/articles/PMC6318016/
Autor:
Michael S. Sacks, João S. Soares
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 15:293-316
While it has become axiomatic that mechanical signals promotes in-vitro engineered tissue formation, the underlying mechanisms remain largely unknown. Moreover, efforts to date to determine parameters for optimal extracellular matrix (ECM) developmen