Zobrazeno 1 - 10
of 13
pro vyhledávání: '"João R. C. Trabuco"'
Autor:
Heather J Goux, Balakrishnan Raja, Katerina Kourentzi, João R C Trabuco, Binh V Vu, Andrew S Paterson, Alexander Kirkpatrick, Blane Townsend, Miles Lee, Van Thi Thanh Truong, Claudia Pedroza, Richard C Willson
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225365 (2019)
Herpes Simplex Virus Type 2 (HSV-2) is a common human pathogen that causes life-long illness. The US prevalence of HSV-2 infection is 11.9% for individuals between 15 and 49 years of age. Individuals with HSV-2 infection are more likely to contract a
Externí odkaz:
https://doaj.org/article/7523d5522d5f4be1b845aaf34f9d3393
Autor:
Maria João Jacinto, João R C Trabuco, Binh V Vu, Gavin Garvey, Mohammad Khodadadi, Ana M Azevedo, Maria Raquel Aires-Barros, Long Chang, Katerina Kourentzi, Dmitri Litvinov, Richard C Willson
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213859 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0186782.].
Externí odkaz:
https://doaj.org/article/ec975b940d96464aa27aebe1fe779b1f
Autor:
Maria João Jacinto, João R C Trabuco, Binh V Vu, Gavin Garvey, Mohammad Khodadady, Ana M Azevedo, Maria Raquel Aires-Barros, Long Chang, Katerina Kourentzi, Dmitri Litvinov, Richard C Willson
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0186782 (2018)
Lateral flow assays (LFAs) are a widely-used point-of care diagnostic format, but suffer from limited analytical sensitivity, especially when read by eye. It has recently been reported that LFA performance can be improved by using magnetic reporter p
Externí odkaz:
https://doaj.org/article/dcd70471ee3d4a9c8fe9d0cbe8e92135
Autor:
João R. C. Trabuco, Alexander Kirkpatrick, Blane Townsend, Miles Lee, Balakrishnan Raja, Heather J. Goux, Andrew S. Paterson, Katerina Kourentzi, Claudia Pedroza, Binh Vu, Richard C. Willson, Van Thi Thanh Truong
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0225365 (2019)
PLoS ONE, Vol 14, Iss 12, p e0225365 (2019)
Herpes Simplex Virus Type 2 (HSV-2) is a common human pathogen that causes life-long illness. The US prevalence of HSV-2 infection is 11.9% for individuals between 15 and 49 years of age. Individuals with HSV-2 infection are more likely to contract a
Autor:
Dmitri Litvinov, Ana Azevedo, Maria João Jacinto, Binh Vu, Long Chang, Katerina Kourentzi, Gavin Garvey, Richard C. Willson, Mohammad Khodadadi, João R. C. Trabuco, Maria Raquel Aires-Barros
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213859 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0186782.].
Autor:
D.M.F. Prazeres, S. A. M. Martins, João R. C. Trabuco, Virginia Chu, João Pedro Conde, G. Moulas, Gabriel A. Monteiro
Publikováno v:
Biosensors and Bioelectronics. 52:232-238
G-protein coupled receptor (GPCRs) drug discovery is a thriving strategy in the pharmaceutical industry. The standard approach uses living cells to test millions of compounds in a high-throughput format. Typically, changes in the intracellular levels
Autor:
Richard C. Willson, Jinsu Kim, João R. C. Trabuco, Ryan Poling-Skutvik, Katerina Kourentzi, Jacinta C. Conrad
Using microscopy and image analysis, we characterize binding of filamentous viral nanoparticles to a fibrous affinity matrix as models for reporter capture in a lateral flow assay (LFA). M13 bacteriophage (M13) displaying an in vivo-biotinylated pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3712d9f369cc0486df14854239e12fec
https://europepmc.org/articles/PMC5167648/
https://europepmc.org/articles/PMC5167648/
Autor:
D. Miguel F. Prazeres, João R. C. Trabuco, S. A. M. Martins, João Pedro Conde, Virginia Chu, Gabriel A. Monteiro
Publikováno v:
Trends in Biotechnology. 30:566-574
G protein-coupled receptors (GPCRs) play a key role in many physiological or disease-related processes and for this reason are favorite targets of the pharmaceutical industry. Although ~30% of marketed drugs target GPCRs, their potential remains larg
Autor:
Katerina Kourentzi, Mohammad Khodadady, Binh Vu, Gavin Garvey, Long Chang, Dmitri Litvinov, João R. C. Trabuco, Maria João Jacinto, Ana Azevedo, Maria Raquel Aires-Barros, Richard C. Willson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0186782 (2018)
PLoS ONE, Vol 13, Iss 1, p e0186782 (2018)
Lateral flow assays (LFAs) are a widely-used point-of care diagnostic format, but suffer from limited analytical sensitivity, especially when read by eye. It has recently been reported that LFA performance can be improved by using magnetic reporter p
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1272
Live-cell assays used in GPCR research often rely on fluorescence techniques that generate large amounts of raw image data. Consequently, the capacity to accurately and timely extract useful information from image and video data has become more and m