Uptake of lipid core nanoparticles by fragments of tissues collected during cerebral tumor excision surgeries: hypotheses for use in drug targeting therapy

Autor: Edmundo Luís Rodrigues Pereira, Danielle Cristinne Azevedo Feio, João Pojucan Lobo Tavares, Natalia Megumi Morikawa, Debora Fernandes Deus, Carolina Graziani Vital, Elaine Rufo Tavares, Raul Cavalcante Maranhão

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Malignant cerebral tumors have poor prognosis and the blood-brain barrier is a major hindrance for most drugs to reach those tumors. Lipid nanoparticles (LDE) that bind to lipoprotein receptors may carry anticancer drugs and penetrate the cells throu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c4c676beff3345665dcb841192a289
https://pubmed.ncbi.nlm.nih.gov/35612697