Zobrazeno 1 - 10
of 93
pro vyhledávání: '"João P. B. Viola"'
Autor:
Thiago Moreno L. Souza, Vagner D. Pinho, Cristina F. Setim, Carolina Q. Sacramento, Rodrigo Marcon, Natalia Fintelman-Rodrigues, Otavio A. Chaves, Melina Heller, Jairo R. Temerozo, André C. Ferreira, Mayara Mattos, Patrícia B. Momo, Suelen S. G. Dias, João S. M. Gesto, Filipe Pereira-Dutra, João P. B. Viola, Celso Martins Queiroz-Junior, Lays Cordeiro Guimarães, Ian Meira Chaves, Pedro Pires Goulart Guimarães, Vivian Vasconcelos Costa, Mauro Martins Teixeira, Dumith Chequer Bou-Habib, Patrícia T. Bozza, Anderson R. Aguillón, Jarbas Siqueira-Junior, Sergio Macedo-Junior, Edineia L. Andrade, Guilherme P. Fadanni, Sara E. L. Tolouei, Francine B. Potrich, Adara A. Santos, Naiani F. Marques, João B. Calixto, Jaime A. Rabi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The search for antivirals against SARS-CoV-2 continue due to the emergence of variants of concerns, able to escape the vaccinal humoral response. In this work, authors pre-clinically explore the potential of kinetin against SARS-CoV-2, which could be
Externí odkaz:
https://doaj.org/article/7d55dbfc83a94333a82eee70353ce909
Autor:
Maria Carolina Viana, Gislaine Curty, Carolina Furtado, Bhavya Singh, Matthew L. Bendall, João P. B. Viola, Andreia Cristina de Melo, Marcelo A. Soares, Miguel A. M. Moreira
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Due to immunosuppressive cancer therapies, cancer patients diagnosed with COVID-19 have a higher chance of developing severe symptoms and present a higher mortality rate in comparison to the general population. Here we show a comparative analysis of
Externí odkaz:
https://doaj.org/article/35ade85c1dd547fbb707629b7c95bc67
Autor:
Livia R. Goes, Juliana D. Siqueira, Marianne M. Garrido, Brunna M. Alves, Claudia Cicala, James Arthos, João P. B. Viola, Marcelo A. Soares
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Chronically immunosuppressed patients infected with SARS-CoV-2 often experience prolonged virus shedding, and may pave the way to the emergence of mutations that render viral variants of concern (VOC) able to escape immune responses induced by natura
Externí odkaz:
https://doaj.org/article/683b97b875b543fbae8d6591900ff81d
Autor:
Vanessa Neitzke-Montinelli, Carolina Calôba, Guilherme Melo, Bianca B. Frade, Enzo Caramez, Luciano Mazzoccoli, André N. A. Gonçalves, Helder I. Nakaya, Renata M. Pereira, Miriam B. F. Werneck, João P. B. Viola
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Long-term immunological protection relies on the differentiation and maintenance of memory lymphocytes. Since the knowledge of memory generation has been centered on in vivo models of infection, there are obstacles to deep molecular analysis of diffe
Externí odkaz:
https://doaj.org/article/618a0bd1306c4679bcb6a137e9955e5c
Autor:
Lívia Teixeira, Jairo R. Temerozo, Filipe S. Pereira-Dutra, André Costa Ferreira, Mayara Mattos, Barbara Simonson Gonçalves, Carolina Q. Sacramento, Lohanna Palhinha, Tamires Cunha-Fernandes, Suelen S. G. Dias, Vinicius Cardoso Soares, Ester A. Barreto, Daniella Cesar-Silva, Natalia Fintelman-Rodrigues, Camila R. R. Pão, Caroline S. de Freitas, Patrícia A. Reis, Eugenio D. Hottz, Fernando A. Bozza, Dumith C. Bou-Habib, Elvira M. Saraiva, Cecília J. G. de Almeida, João P. B. Viola, Thiago Moreno L. Souza, Patricia T. Bozza
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical studies, statins have been identified as beneficial to hospitalized patients with
Externí odkaz:
https://doaj.org/article/39df5290aece4fe5890ecbf76dc10dc2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Interferon regulatory factor 2-binding protein 2 (IRF2BP2) encodes a member of the IRF2BP family of transcriptional regulators, which includes IRF2BP1, IRF2BP2, and IRF2BPL (EAP1). IRF2BP2 was initially identified as a transcriptional corepressor tha
Externí odkaz:
https://doaj.org/article/7609da8ec86f45afad87ec92eb4de161
Autor:
Otávio Augusto Chaves, Carolina Q. Sacramento, André C. Ferreira, Mayara Mattos, Natalia Fintelman-Rodrigues, Jairo R. Temerozo, Leonardo Vazquez, Douglas Pereira Pinto, Gabriel P. E. da Silveira, Laís Bastos da Fonseca, Heliana Martins Pereira, Aluana Santana Carlos, Joana C. d’Avila, João P. B. Viola, Robson Q. Monteiro, Patrícia T. Bozza, Hugo Caire Castro-Faria-Neto, Thiago Moreno L. Souza
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 21 (2021)
Atazanavir (ATV) has already been considered as a potential repurposing drug to 2019 coronavirus disease (COVID-19); however, there are controversial reports on its mechanism of action and effectiveness as anti-severe acute respiratory syndrome coron
Externí odkaz:
https://doaj.org/article/fecc3e0ccd4849ebbf28cd15d63ee8a1
Autor:
Luciana Benevides, Verônica M. Saltarelli, Franciele Pioto, Laís A. Sacramento, Murilo S. Dias, Gretel R. Rodríguez, João P. B. Viola, Vanessa Carregaro, João S. Silva
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes play key roles in the maintenance of homeostasis and in the control of the infection. Monocytes are recruited from the bone marrow to inflammatory sites and are essential for antimicrobial activity to limit tissue damage and promote adaptiv
Externí odkaz:
https://doaj.org/article/188c0c7ddea04132a5d3eb0e9922be07
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Interferon- (IFN-) γ is an essential cytokine for immunity against intracellular pathogens and cancer. IFN-γ expression by CD4 T lymphocytes is observed only after T helper (Th) 1 differentiation and there are several studies about the molecular me
Externí odkaz:
https://doaj.org/article/6006d828af264664a1eb16864eaf4079
Autor:
Etel R. Gimba, Georg F. Weber, João P. B. Viola, Kivvi Duarte de Mello, Fabrício Ribeiro de Azevedo da Silva, João Luiz Mendes Wanderley, Bruno Kaufmann Robbs, Vanessa Ferreira Franco, Tatiana M. Tilli
Ovarian carcinoma is one of the most aggressive gynecological diseases and generally diagnosed at advanced stages. Osteopontin (OPN) is one of the proteins overexpressed in ovarian cancer and is involved in tumorigenesis and metastasis. Alternative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f29f6bd670144dae21691817e62e7a
https://doi.org/10.1158/1541-7786.c.6542001
https://doi.org/10.1158/1541-7786.c.6542001
