Zobrazeno 1 - 10
of 251
pro vyhledávání: '"João P C Tomé"'
Autor:
Patrícia M R Pereira, Naxhije Berisha, N V S Dinesh K Bhupathiraju, Rosa Fernandes, João P C Tomé, Charles Michael Drain
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177737 (2017)
Photodynamic Therapy (PDT) relies on the use of non-toxic photosensitizers that are locally and selectively activated by light to induce cell death or apoptosis through reactive oxygen species generation. The conjugation of porphyrinoids with sugars
Externí odkaz:
https://doaj.org/article/174b46b7ca4d44eaac7deb6b980e92a8
Autor:
Patrícia M R Pereira, Sandrina Silva, José A S Cavaleiro, Carlos A F Ribeiro, João P C Tomé, Rosa Fernandes
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95529 (2014)
Photosensitizers (PSs) are of crucial importance in the effectiveness of photodynamic therapy (PDT) for cancer. Due to their high reactive oxygen species production and strong absorption in the wavelength range between 650 and 850 nm, where tissue li
Externí odkaz:
https://doaj.org/article/78d4832d3edf4d419f15e5ef5601d3e9
Autor:
Eliana Alves, Maria A F Faustino, João P C Tomé, Maria G P M S Neves, Augusto C Tomé, José A S Cavaleiro, Ângela Cunha, Newton C M Gomes, Adelaide Almeida
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20970 (2011)
BackgroundPhotodynamic antimicrobial chemotherapy (PACT) combines light, a light-absorbing molecule that initiates a photochemical or photophysical reaction, and oxygen. The combined action of these three components originates reactive oxygen species
Externí odkaz:
https://doaj.org/article/38d75252bf5c445293eff9e103d3375e
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 330 (2023)
Photodynamic therapy (PDT) stands as an approved clinical treatment for both oncologic and nononcologic disorders [...]
Externí odkaz:
https://doaj.org/article/1b08cb98ce50444a90634fadda8f710a
Publikováno v:
Molecules, Vol 27, Iss 10, p 3111 (2022)
Metal-Organic Frameworks (MOFs) are hybrid multifunctional platforms that have found remarkable applications in cancer treatment and diagnostics. Independently, these materials can be employed in cancer treatment as intelligent drug carriers in chemo
Externí odkaz:
https://doaj.org/article/8f4c1f7fcbd04f2ab04bdaf2660d937f
Autor:
Ana M. Santiago, Carla I. M. Santos, Leandro M. O. Lourenço, Inês F. A. Mariz, João P. C. Tomé, Ermelinda Maçôas
Publikováno v:
Nanomaterials, Vol 12, Iss 11, p 1892 (2022)
Supramolecular hybrids of graphene quantum dots (GQDs) and phthalocyanine (Pc) dyes were studied as turn-OFF-ON photoluminescence nanosensors for detection of ds-DNA. Pcs with four (Pc4) and eight (Pc8) positive charges were selected to interact with
Externí odkaz:
https://doaj.org/article/b7e46f9dd70d46888cfd4adaf802a0c7
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :A-G
In recent years, much attention has been devoted to synthesizing and preparing novel expanded porphyrin architectures. Here we report the selective substitution of the [Formula: see text]-fluorine atoms of meso-hexakis(pentafluorophenyl)[Formula: see
Autor:
José C. Pereira, Patrícia M. R. Pereira, Sandra Beirão, Henrique Girão, João P. C. Tomé, Rosa Fernandes
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 27:471-478
PorGal8, a porphyrin conjugated with dendritic galactose units, binds to galectin-1 in bladder cancer cells and induces localized cell death after light activation. Although it has been previously shown that photodynamic treatment (PDT) affects the c
Publikováno v:
More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles. :333-355
Autor:
Kelly Aparecida Dias de Freitas Castro, João P. C. Tomé, Shirley Nakagaki, Patrícia Pereira, Sandrina Silva, José A. S. Cavaleiro, Mário M.Q. Simões, Maria da Graça P. M. S. Neves, Kátia C. M. Westrup
Publikováno v:
European Journal of Inorganic Chemistry. 2021:2857-2869